Results 91 to 100 of about 1,342,432 (229)
Acta Paediatrica, EarlyView.ABSTRACT Aim To retrospectively collect clinical data of children affected by surgical complications resulting from foreign body ingestion, in order to describe the features of the involved foreign bodies and to analyse the different surgical complications related to their ingestion.
Alessia Salatto +13 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, EarlyView.Placebo arms show substantial improvement in cholestatic pruritus, with up to 30% response rate. Estimates differed across outcome instruments, highlighting the importance of endpoint selection and realistic placebo assumptions in future trial design.
Igor Boechat Silveira +8 more
wiley +1 more source
Uncovering male and female experiences of irritable bowel syndrome
, 2015 Implications for practice and research:- A more gender sensitive approach in the healthcare setting could increase understanding of patients’ experience of irritable bowel syndrome (IBS).- Intervention studies from a person centred, gender-sensitive ...
Smith, Graeme D
core +1 more source
Birth, EarlyView.ABSTRACT Background Postpartum health‐related problems are diverse, and some may extend beyond the first postpartum year. The purpose of this study was to describe women's postpartum health problems in the first and second postpartum years. Methods We analyzed data from an online survey (N = 427) conducted in 2024.
Sudhathai Sirithepmontree +2 more
wiley +1 more source
New biosensors and transgenic mice for multiplex cGMP imaging
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters +6 more
wiley +1 more source
Zdorovʹe RebenkaBackground. Functional dyspepsia and irritable bowel syndrome are the most prevalent functional gastrointestinal disorders among school-aged children.
N.A. Sliusar, S.P. Kryvopustov
doaj +1 more source
The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Practical Evaluation and Handling of Patients with Irritable Bowel Syndrome [PDF]
, 2012 Irritable bowel syndrome (IBS) is a functional bowel disorder by unknown aetiology. Several reviews are written about pharmacological and psychological treatment of the disease.
Bodil Ohlsson, Ohlsson, Bodil
core
British Journal of Pharmacology, EarlyView.Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz +8 more
wiley +1 more source
The Turkish Journal of Pediatrics, 2014 Scarce data exist concerning the prevalence of irritable bowel syndrome in adolescence. Changes in lifestyle, presence of stressors and psychological vulnerability during this stage of life place adolescents in the risk group for irritable bowel ...
Gökhan Baysoy +5 more
doaj