Results 251 to 260 of about 60,019 (290)

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

Spatial and Functional Specialization of Gut Enterochromaffin Cells in Sensory Signaling. [PDF]

Gastroenterology
Najjar SA, Margolis KG.
europepmc   +1 more source

Biomarker-Based Diagnosis of Contact Dermatitis: A Step Towards More Accurate and Patient-Friendly Testing. [PDF]

Clin Pract
Grob N, Rustemeyer T, de Boer F.
europepmc   +1 more source

Excessive dynamic airway collapse: A condition behind the veil. [PDF]

World J Methodol
Paudyal V, Thapa R, Itani A, Sharma M, Rayamajhi R, Ratnani I, Surani S.   +6 more
europepmc   +1 more source

Coolants, organic acids, flavourings and other additives that facilitate inhalation of tobacco and nicotine products: implications for regulation. [PDF]

Tob Control
Talhout R, Leventhal AM.
europepmc   +1 more source

Barrier Products for Topical Delivery-Insight into Efficacy Testing and Barrier-Boosting Compounds. [PDF]

Pharmaceutics
Bagińska ZH, Szymańska E.
europepmc   +1 more source

Orbito-cranial penetrating head injury by tear gas canister: A case report. [PDF]

Surg Neurol Int
Alhadeethi BM, Sarhan AE, Sheikh ON, Al-Ghuraibawi MA, Muthana A, Hoz SS.   +5 more
europepmc   +1 more source

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Getting irritable about irritability?

Evidence Based Mental Health, 2019
Despite irritability being considered a symptom of several psychiatric disorders, there is no standardised definition or measurement of the construct within psychiatry. This lack of definition is in part due to a fundamental lack of understanding of what it means to be irritable and the foundational mechanisms that lead to its manifestation.
Gin Malhi, Erica Bell, Tim Outhred
openaire   +2 more sources