Results 31 to 40 of about 3,861 (149)

Isaacs Syndrome in A Patient with Positive CASPR2 And LGI1 Antibodies: A Case Report and Literature Review

Case Reports in Clinical Practice
Isaacs Syndrome (IS) is an autoimmune disease characterized by fasciculations, dysautonomia, and hyperactivity of muscle fibers due to hyperexcitability of the peripheral nerve system.
Rasa Zafari, Mona Ahmadi
doaj   +1 more source

Seven Decades of Demographic Trends at the Hugo Awards From 1953 to 2023: How the Award Recipients Reflect Actual and Aspirational Demographic Trends in Society

Sociology Lens, EarlyView.
ABSTRACT This study analyses the demographic trends at the Hugo Awards, with a focus on the authors' genders, languages, nationalities, and uses of pseudonyms. This research uses publicly available information published by the World Science Fiction Society and the Hugo Awards to determine demographic trends in nominated and winning authors for the Best
Grace Boglev
wiley   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Isaacs’s syndrome and associated diseases

Rinsho Shinkeigaku, 2013
Isaacs' syndrome is an antibody-mediated potassium channel disorder. Clinical symptoms of Isaacs' syndrome are characterized by muscle cramp, slow relaxation following muscle contraction, and hyperhidrosis. Hyperexcitability of the peripheral nerve cause these symptoms, which are relieved by administration of Na channel blockers and immunotherapy.The ...
openaire   +3 more sources

Brain Abscess Revealing an Undiagnosed Atrioventricular Septal Defect With a Common Atrium in a Young Adult

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Brain abscess is an uncommon but life‐threatening intracranial infection that most often arises from contiguous spread but may also occur through hematogenous dissemination in patients with congenital heart disease. This is usually associated with defects that permit right‐to‐left shunting of septic emboli.
Evans Nii Ayitey MacCready, Ama Owusuaa Kwakye, Kelvin Denanyoh, Hilda Kwapong, Isaac Nene Keteku, Jochebed Ansah, Werman Reve Robles   +6 more
wiley   +1 more source

Clinical Spectrum of Focal Dystonia in Patients at Tertiary Care Hospital in Karachi: A Cross-Sectional Study

Journal of University College of Medicine and Dentistry
Objective: To describe the clinical patterns and types of focal dystonia among patients presenting to the neurology department of a tertiary care hospital in Karachi. Methodology: This descriptive cross-sectional study was undertaken at Dr. Ruth K. M.
Rabiya Khan, Qamar-Un-Nisa, Sidra Jazil Faruqi, Sumera Rafat Umer, Rabia Iqbal, Wajid Jawaid   +5 more
doaj   +1 more source

Hospital admissions and school absences of primary school children with and without neurodisability

Developmental Medicine &Child Neurology, Volume 68, Issue 7, Page 938-951, July 2026.
Abstract Aim To inform integrated support by education and health services by comparing hospitalization and school absence rates during primary school in children with and without neurodisability. Method In this linked administrative data cohort study, we followed 2 351 589 children born in England between 2003 and 2008 from enrolment in Reception ...
Laura Gimeno, Ania Zylbersztejn, Ayana Cant, Ruth Gilbert, Katie Harron, on behalf of the HOPE Study Group, Sarah Barnes, Kate Boddy, Kristine Black‐Hawkins, Lorraine Dearden, Bianca De Stavola, Johnny Downs, William Farr, Tamsin Ford, Lucy Karwatowska, Kate Lewis, Matthew Lilliman, Jacob Matthews, Stuart Logan, Vincent Nguyen, Jugnoo Rahi, Jennifer Saxton, Joachim Tan, Isaac Winterburn   +23 more
wiley   +1 more source

Myokymia of lower limbs for over one year

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
A 51-year-old man came to our outpatient for one-year history of progressive myokymia in both legs. He had initially noted a “continuous muscle-fiber activity” of lower limbs in July 2013. Two months later, similar symptoms progressively affected muscles
Jing ZHAO, Li-ling DONG, Yin-chang YANG, Li-ying CUI   +3 more
doaj  

Sensory Hypersensitivity Severity and Association with Obsessive-Compulsive Symptoms in Adults with Tic Disorder

Neuropsychiatric Disease and Treatment, 2020
David Isaacs,1 Alexandra P Key,2– 4 Carissa J Cascio,4– 6 Alexander C Conley,2,6 Harrison C Walker,7 Mark T Wallace,3,5,6,8,9 Daniel O Claassen1 1Department of Neurology, Vanderbilt University Medical Center, Nashville, TN, USA; 2Center for ...
Isaacs D, Key AP, Cascio CJ, Conley AC, Walker HC, Wallace MT, Claassen DO   +6 more
doaj