In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma +20 more
wiley +1 more source
Association between ischemia-modified albumin (IMA) and peripheral endothelial dysfunction in rheumatoid arthritis patients. [PDF]
Erre GL +9 more
europepmc +1 more source
Abstract Background Clinical services for adults with early‐onset type 2 diabetes (EOT2D) are in urgent need of improvement. Methods We evaluated a multi‐disciplinary clinic for individuals with EOT2D at high risk (HbA1c >9%/triglyceride >20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025 ...
Jonathan Goldney +14 more
wiley +1 more source
Comparison of serum ischemia modified albumin levels between preeclamptic and healthy pregnant women. [PDF]
Zuhal D +6 more
europepmc +1 more source
ABSTRACT Aims Diabetic peripheral neuropathy (DPN) may be linked to central nervous system changes. This study examined if DPN is associated with an increased risk of incident dementia and cerebrovascular disease in individuals with Type 1 (T1D) and Type 2 diabetes (T2D). Materials and Methods This register‐based cohort study (1998–2020) used data from
Astrid Wiggers +9 more
wiley +1 more source
The effect of major depressive disorder comorbidity on ischemia-modified albumin levels, a marker of oxidative stress, and antioxidant defense system in patients with obsessive compulsive disorder. [PDF]
Zengil S, Laloğlu E.
europepmc +1 more source
Prediabetes, Malignant Ventricular Hypertrophy and Stroke: The SPRINT Trial
ABSTRACT Aims Prediabetes and left ventricular hypertrophy (LVH) are common risk factors in adults with hypertension. Whether their coexistence, particularly in the presence of subclinical myocardial injury or stress (malignant LVH), confers a heightened stroke risk is unknown.
Arnaud D. Kaze +7 more
wiley +1 more source
Ischemia-modified albumin: a novel blood marker of endoscopic mucosal healing in inflammatory bowel disease. [PDF]
Lee SB +4 more
europepmc +1 more source
GIP in Cardiovascular and Kidney Disease: From Physiology to Pharmacology
ABSTRACT Aims To provide a comprehensive overview of the cardiovascular and renal effects of glucose‐dependent insulinotropic polypeptide (GIP) by integrating its physiological role with recent human trial data on tirzepatide, the first dual GIP and glucagon‐like peptide‐1 (GLP‐1) receptor agonist.
Michelantonio De Fano +4 more
wiley +1 more source
Diagnostic and prognostic value of serum Cys-C, retinol-binding protein, and ischemia-modified albumin in patients with coronary heart disease: A diagnostic accuracy study. [PDF]
Yuan Y +5 more
europepmc +1 more source

