Results 281 to 290 of about 1,336,017 (348)

Gadd45α silencing alleviates cerebral ischemia-reperfusion injury by suppressing FOXO1 signaling. [PDF]

Sci Rep
Chen C, Tao W, Chen F, Gong J.
europepmc   +1 more source

Mixed lineage kinase 3 mediates SARS‐CoV‐2‐induced kidney injury via the Hsp70‐IL‐17A axis

Interdisciplinary Medicine, EarlyView.
Kidney samples from patients infected with severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) showed upregulated expression and activity of Mixed Lineage Kinase (MLK3). Based on the mechanistic studies, we identified MLK3 as a critical player in promoting SARS‐CoV‐2‐induced kidney injury.
Sandeep Kumar, Sunil Kumar Singh, Piush Srivastava, Sowdhamini Mahendiran, Rakesh Sathish Nair, Harsh Vyas, Saket Jha, Niraj Nag, Navin Viswakarma, Hitesh Kapoor, Swathi Suresh, Periannan Sethupathi, Sang‐Ging Ong, Jerrold S. Levine, Suman Setty, Mathayan Manikannan, Bellur S. Prabhakar, Basabi Rana, Ajay Rana   +18 more
wiley   +1 more source

Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis. [PDF]

Int J Mol Med
Chen X, Zhao J, He X, Zhang Y, Wu J, Jiang C, Yang Y, Xiao J.   +7 more
europepmc   +1 more source

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Development of a Porcine Model of Pulmonary Ischemia-Reperfusion Injury Relevant to Post-Esophagectomy Acute Respiratory Distress Syndrome. [PDF]

Med Sci (Basel)
Hafezi M, Saffari A, Khajeh E, Flechtenmacher C, Lichtenstern C, Mehrabi A, Garoussi C.   +6 more
europepmc   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

ELABELA: A Potential Therapeutic Target for Ischemia-Reperfusion Injury. [PDF]

Biomolecules
Li W, Meng C, Yang S, Xie Y, Huang Z, Wang T.   +5 more
europepmc   +1 more source

NUAK1 Inhibition Alleviates Ischemia-Reperfusion Injury via SYNE1-YAP1. [PDF]

Circ Res
Bai Y, Zhao T, Wang Q, Zhang R, Wei Z, Fei Y, Cai X, Wu Z, Yan J, Zhang Y, Chen K, Wang Y, Li YG.   +12 more
europepmc   +1 more source

Histological Evaluation of Insulin-like Growth Factor-I in Experimental Intestinal Ischemia-Reperfusion Injury: A Rat Study. [PDF]

Diseases
Andronikou A, Psalla D, Ioannidis R, Papalois A, Iliadis S, Dinaki K, Kamparoudis A.   +6 more
europepmc   +1 more source

Maturation is required to model ischemia-reperfusion injury in engineered human cardiac tissues. [PDF]

Front Bioeng Biotechnol
Nash TR, Lock RI, Li VYR, Lamberti MJ, Kim Y, Sanchez E, Fleischer S, Tavakol DN, Vunjak-Novakovic G.   +8 more
europepmc   +1 more source