Results 1 to 10 of about 199,098 (313)
Pyroptosis: Novel Targets in Molecular Mechanisms and Drug Therapy Research for Myocardial Ischemia Reperfusion Injury [PDF]
Reviews in Cardiovascular MedicineMyocardial ischemia-reperfusion injury is a significant complication of reperfusion therapy and a primary cause of mortality in patients with acute myocardial infarction.
Dong Zhang +6 more
doaj +2 more sources
Frontiers in Medicine, 2023 ObjectiveLung ischemia/reperfusion injury (LIRI) is a clinical syndrome of acute lung injury that occurs after lung transplantation or remote organ ischemia.
Xiujie Liu +15 more
doaj +1 more source
Gut Microbes, 2023 Symbiotic microbiota critically contribute to host immune homeostasis in effector cell-specific manner. For exclusion of microbial component, germ-free animals have been the gold standard method.
Da-Jung Jung +6 more
doaj +1 more source
Free Radical Biology and Medicine, 1988 Several lines of evidence point to a major role of oxygen free radicals in the pathogenesis of cell death or dysfunction in a variety of disease processes. Recent studies from this as well as other laboratories have demonstrated that oxygen free radicals play a major role in the pathogenesis of post-ischemic reperfusion injury in the heart.
J T, Flaherty, M L, Weisfeldt
+5 more sources
Unconventional immune cells in the gut mucosal barrier: regulation by symbiotic microbiota
Experimental and Molecular Medicine, 2023 The mammalian gut is the most densely colonized organ by microbial species, which are in constant contact with the host throughout life. Hosts have developed multifaceted cellular and molecular mechanisms to distinguish and respond to benign and ...
Ji-Sun Yoo, Sungwhan F. Oh
doaj +1 more source
Frontiers in Immunology, 2021 The resolution of the acute inflammatory response is governed by phagocytes actively clearing apoptotic cells and pathogens. Biosynthesis of the specialized pro-resolving mediators (SPMs) is pivotal in the resolution of inflammation via their roles in ...
Stephania Libreros +6 more
doaj +1 more source
Reperfusion Injury after Acute Myocardial Infarction [PDF]
, 2022 Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. Primary percutaneous coronary intervention (PPCI) is the gold standard treatment for patients presenting with ST-segment elevation myocardial infarction (STEMI ...
Ishikawa, Tetsuya +11 more
core +1 more source
Biomedicines, 2021 Hepatocellular carcinoma has become a leading cause of cancer-associated mortality throughout the world, and is of great concern. Currently used chemotherapeutic drugs in the treatment of hepatocellular carcinoma lead to severe side effects, thus ...
Ana I. Álvarez-Mercado +8 more
doaj +1 more source
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
, 1997 Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian +6 more
core +1 more source
Natural Product Communications, 2015 The effect of puerarin (Pur) on expressions of Fas/FasL mRNAs in pulmonary ischemia and reperfusion injury (PIRI) in rabbit was investigated. The sole side lung ischemia and reperfusion model was used.
Mengxiao Zheng +5 more
doaj +1 more source