Results 21 to 30 of about 340,285 (357)

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

open access: yesNature Communications, 2018
Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections.
Oliver Werz   +7 more
doaj   +1 more source

Heat Shock Protein 70 Protects the Heart from Ischemia/Reperfusion Injury through Inhibition of p38 MAPK Signaling. [PDF]

open access: yes, 2020
BackgroundHeat shock protein 70 (Hsp70) has been shown to exert cardioprotection. Intracellular calcium ([Ca2+]i) overload induced by p38 mitogen-activated protein kinase (p38 MAPK) activation contributes to cardiac ischemia/reperfusion (I/R) injury ...
Chen, Qing-Cai   +10 more
core   +1 more source

Lipid Mediator Informatics and Proteomics in Inflammation-Resolution

open access: yesThe Scientific World Journal, 2006
Lipid mediator informatics is an emerging area denoted to the identification of bioactive lipid mediators (LMs) and their biosynthetic profiles and pathways.
Yan Lu   +3 more
doaj   +1 more source

Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Diabetic patients are susceptible to renal ischemia-reperfusion injury, which leads to perioperative complications. Activation of NOD-like receptor protein 3 (NLRP3) inflammasome participates in the development of diabetes, and contributes to ...
Seung Hyun Kim   +5 more
doaj   +1 more source

Recanalization and reperfusion in acute ischemic stroke. [PDF]

open access: yes, 2010
Revascularization remains the most intuitive strategy to reverse ischemic injury associated with arterial occlusion in acute stroke. Revascularization may lead to opening of an occluded artery, or recanalization, yet restoration of downstream flow, or ...
Liebeskind, David S
core   +2 more sources

Electroacupuncture Pretreatment Mitigates Myocardial Ischemia/Reperfusion Injury via XBP1/GRP78/Akt Pathway

open access: yesFrontiers in Cardiovascular Medicine, 2021
Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang   +9 more
doaj   +1 more source

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

open access: yes, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P   +5 more
core   +1 more source

Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins

open access: yesThe Scientific World Journal, 2002
It is well appreciated that lipid-derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved.
Charles N. Serhan, Nan Chiang
doaj   +1 more source

Reperfusion injury

open access: yesClinical Cardiology, 1990
AbstractThis article reviews the early and late morphologic changes associated with reperfusion of ischemic myocardium. If instituted within minutes of coronary artery occlusion, all reversibly injured myocardium is salvaged. Once some irreversibly injured myocardium is present, the usually bland region of coagulation necrosis is transformed into an ...
openaire   +2 more sources

Postconditioning: Reperfusion of “reperfusion injury” after hibernation [PDF]

open access: yesCardiovascular Research, 2006
The newly developed concept of postconditioning as a way of reducing reperfusion injury has been receiving much attention in the literature, both in basic science and clinical circles. Cardiovascular Research will be hosting a Spotlight Issue entitled “ Cardiac Protection by Pre- and Postconditioning ” in May of this year.
David, Garcia-Dorado   +1 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy