Results 1 to 10 of about 7,733 (208)

Role of Resolvins in Inflammatory and Neuropathic Pain

Pharmaceuticals, 2023
Chronic pain is an unpleasant experience associated with actual or potential tissue damage. Inflammatory pain alerts the body to inflammation and promotes healing; however, unresolved inflammation can lead to chronic pain.
Jaeik Park, Jueun Roh, Jingying Pan, Yong Ho Kim, Chul-Kyu Park, Youn Yi Jo   +5 more
doaj   +4 more sources

Resolvins, Protectins, and Maresins: DHA-Derived Specialized Pro-Resolving Mediators, Biosynthetic Pathways, Synthetic Approaches, and Their Role in Inflammation

Molecules, 2022
Marine organisms are an important source of natural products with unique and diverse chemical structures that may hold the key for the development of novel drugs.
Narcisa M Bandarra, Amelia P Rauter, Bandarra Narcisa   +2 more
exaly   +4 more sources

Resolution of Inflammation after Skeletal Muscle Ischemia–Reperfusion Injury: A Focus on the Lipid Mediators Lipoxins, Resolvins, Protectins and Maresins

Antioxidants, 2022
Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig, Gaëtan Lutzweiler, Margherita Giannini   +2 more
exaly   +4 more sources

The Role of Resolvins, Protectins and Marensins in Non-Alcoholic Fatty Liver Disease (NAFLD)

Biomolecules, 2021
Increased triacylglycerols’ (TAG) synthesis, insulin resistance, and prolonged liver lipid storage might lead to the development of non-alcoholic fatty liver disease (NAFLD).
Dominika Maciejewska, Ewa Stachowska, Laura Stachowska   +2 more
exaly   +4 more sources

Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins

Mediators of Inflammation, 2020
Acute inflammation has been described as a reactive dynamic process, promoted by the secretion of proinflammatory mediators, including lipid molecules like leukotrienes and prostaglandins, and counterbalanced by proresolving mediators including omega-3 ...
Sajad Chamani, Vanessa Bianconi, Aida Tasbandi, Matteo Pirro, George E. Barreto, Tannaz Jamialahmadi, Amirhossein Sahebkar   +6 more
doaj   +3 more sources

Role play of regulatory T cells and resolvins in type 2 diabetes [PDF]

Frontiers in Immunology
Low-grade systemic inflammation is seen in type 2 diabetes mellitus (T2DM), which is also considered the underlying mechanism for the occurrence of major complications observed in these patients.
Sandhya Krishnan, Shriraam Mahadevan, Hanuman Prasad Sharma, Undurti Narasimha Das, Kaviarasan Kuppan   +4 more
doaj   +2 more sources

Immunomodulation of periodontitis with SPMs

Frontiers in Oral Health, 2023
Inflammation is a critical component in the pathophysiology of numerous disease processes, with most therapeutic modalities focusing on its inhibition in order to achieve treatment outcomes.
Vaibhav Sahni, Thomas E. Van Dyke, Thomas E. Van Dyke   +2 more
doaj   +1 more source

A combination treatment of low-dose dexamethasone and aspirin-triggered resolvin D1 reduces Sjögren syndrome–like features in a mouse modelWhy Is This Important?

JADA Foundational Science, 2023
Background: Sjögren syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration and diminished secretory function of the salivary glands. Dexamethasone (DEX) resolves dry mouth and lymphocytic infiltration; however, this treatment is
Harim Tavares dos Santos, DDS, PhD, Frank Maslow, BS, Kihoon Nam, PhD, Bryan Trump, DDS, Gary A. Weisman, PhD, Olga J. Baker, DDS, PhD   +5 more
doaj   +1 more source

The Impact of the Ca²⁺-Independent Phospholipase A₂β (iPLA₂β) on Immune Cells

Biomolecules, 2021
The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including membrane remodeling, cell proliferation, bone formation, male fertility, cell death, and ...
Tayleur D. White, Abdulaziz Almutairi, Ying Gai Tusing, Xiaoyong Lei, Sasanka Ramanadham   +4 more
doaj   +1 more source

Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 Infection

Frontiers in Immunology, 2020
Obesity is a major independent risk factor for increased morbidity and mortality upon infection with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which is responsible for the current coronavirus disease pandemic (COVID-19).
Anandita Pal, Kymberly M. Gowdy, Kenneth J. Oestreich, Melinda Beck, Saame Raza Shaikh   +4 more
doaj   +1 more source