Results 41 to 50 of about 7,733 (208)
Frontiers in Immunology, 2020 G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of ...
Patricia R. Souza +8 more
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Infection, Inflammation, and Immunity in Sepsis
Biomolecules, 2023 Sepsis is triggered by microbial infection, injury, or even major surgery. Both innate and adaptive immune systems are involved in its pathogenesis. Cytoplasmic presence of DNA or RNA of the invading organisms or damaged nuclear material (in the form of ...
Undurti N. Das
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Major structure-activity relationships of resolvins, protectins, maresins and their analogues
, 2023 Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived molecules which play important roles in the resolution of inflammation.
O'Sullivan, Killian +2 more
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Protectin and resolvin gut inflammation [PDF]
Science, 2017 Inflammation Even when laced with syrup, cod-liver oil is disgusting, but it is an important source of omega-3-docosapentaenoic fatty acid (DPA). After being swallowed, DPA is converted into specialized proresolving lipid mediators (SPMs), including protectin and resolvin.
openaire +2 more sources
Frontiers in Pharmacology, 2021 Sevoflurane (SEV), a commonly used volatile anesthetic, has been shown to cause cognitive decline in diabetic rats by aggregating neuroinflammation in the hippocampus, but the underlying mechanisms are unknown.
Qingmei Sun +6 more
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Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses [PDF]
The Journal of Immunology, 2012 Abstract Asthma is a disease of airway inflammation that in most cases fails to resolve. The resolution of inflammation is an active process governed by specific chemical mediators, including D-series resolvins. In this study, we determined the impact of resolvin D1 (RvD1) and aspirin-triggered RvD1 (AT-RvD1) on the development of ...
Alexandre P, Rogerio +9 more
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A modular, enantioselective synthesis of resolvins D3, E1, and hybrids
, 2020 Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama-Denmark coupling of five- and six-membered cyclic alkenylsiloxanes ...
Streatfeild, Penelope E +4 more
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Journal of Lipid Research, 2013 Placental inflammation is associated with several pregnancy disorders. Inflammation is limited by anti-inflammatory and proresolving mechanisms, the latter partly mediated by resolvins and protectins derived from omega-3 polyunsaturated fatty acids (n ...
Megan L. Jones +6 more
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Role of Resolvins in the Inflammatory Resolution of Neurological Diseases
Frontiers in Pharmacology, 2020 The occurrence of neurological diseases including neurodegenerative disorders, neuroimmune diseases, and cerebrovascular disorders is closely related to neuroinflammation. Inflammation is a response against infection or injury. Genetic abnormalities, the
Chunrong Li +6 more
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The role of Resolvin D1 in liver diseases
Prostaglandins & Other Lipid Mediators, 2022 The liver is a parenchymatous organ closely related to immunity, detoxification and metabolism of the three major nutrients. The inflammatory response is a protective mechanism of the body to eliminate harmful stimuli. However, continuous inflammatory stimulation leads to occurrence of many liver diseases and brings great social burden.
Mei, Yang +3 more
openaire +2 more sources