Results 41 to 50 of about 10,096 (216)
Resolvins on the way to resolution [PDF]
Journal of Experimental Medicine, 2015 ![Figure][1] Insight from Peter Ward Over the past several decades, lipid products have been found to exert both proinflammatory effects (e.g., prostaglandins and leukotrienes) and antiinflammatory activities (e.g., lipoxins and products derived from docosahexaenoic acid ...
openaire +2 more sources
Is There a Role for Bioactive Lipids in the Pathobiology of Diabetes Mellitus?
Frontiers in Endocrinology, 2017 Inflammation, decreased levels of circulating endothelial nitric oxide (eNO) and brain-derived neurotrophic factor (BDNF), altered activity of hypothalamic neurotransmitters (including serotonin and vagal tone) and gut hormones, increased concentrations ...
Undurti N. Das, Undurti N. Das
doaj +1 more source
Lipoxins and Resolvins in Patients With Pancreatic Cancer: A Preliminary Report
Frontiers in Oncology, 2022 Eicosanoids are bioactive lipids derived from arachidonic acid, which have emerged as key regulators of a wide variety of pathophysiological processes in recent times and are implicated as mediators of gastrointestinal cancer.
W. Błogowski +4 more
semanticscholar +1 more source
Resolvins as Regulators of the Immune System [PDF]
The Scientific World JOURNAL, 2010 Inflammation is the first response of the immune system to infection or injury, but excessive or inappropriate inflammatory responses contribute to a range of acute and chronic human diseases. Clinical assessment of dietary supplementation of ω-3 polyunsaturated fatty acids (i.e., eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) indicate ...
Hiroyuki Seki +3 more
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RSC Advances, 2022 The first total convergent synthesis of 4(S),5(S)-oxido-17(S)-hydroxy-6(E),8(E),10(Z),13(Z),15(E),19(Z)-docosahexaenoic acid (1) is described. The reported synthesis led to confirmation of the native epoxydocosahexaenoic acid as the biosynthetic ...
Robert Nshimiyimana +4 more
semanticscholar +1 more source
Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents
Chemistry & Biology, 2013 Resolvins are a family of n-3 lipid mediators initially identified in resolving inflammatory exudates that temper inflammatory responses to promote catabasis. Here, temporal metabololipidomics with self-limited resolving exudates revealed that resolvin (Rv) D3 has a distinct time frame from other lipid mediators, appearing late in the resolution phase.
Dalli, Jesmond +7 more
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Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat [PDF]
The Journal of Immunology, 2012 Abstract The unprecedented increase in the prevalence of obesity and obesity-related disorders is causally linked to a chronic state of low-grade inflammation in adipose tissue. Timely resolution of inflammation and return of this tissue to homeostasis are key to reducing obesity-induced metabolic dysfunctions.
Joan, Clària +4 more
openaire +2 more sources
The Involvement of Resolvins in Pathological Mechanisms of Periodontal Disease Associated with Type 2 Diabetes: A Narrative Review [PDF]
International Journal of Molecular SciencesLiliana Foia +2 more
exaly +2 more sources
Resolvins suppress tumor growth and enhance cancer therapy
Journal of Experimental Medicine, 2018 Cancer therapy reduces tumor burden by killing tumor cells, yet it simultaneously creates tumor cell debris that may stimulate inflammation and tumor growth. Thus, conventional cancer therapy is inherently a double-edged sword.
M. Sulciner +20 more
semanticscholar +1 more source
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Archives of Medical Science, 2021 COVID-19 is caused by SARS-CoV-2 infection. Epithelial and T, NK, and other immunocytes release bioactive lipids especially arachidonic acid (AA) in response to microbial infections to inactivate them and upregulate the immune system.
Undurti N. Das
doaj +1 more source