Results 41 to 50 of about 8,166 (214)
Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Potent Immunoresolvents
Chemistry & Biology, 2013 Resolvins are a family of n-3 lipid mediators initially identified in resolving inflammatory exudates that temper inflammatory responses to promote catabasis. Here, temporal metabololipidomics with self-limited resolving exudates revealed that resolvin (Rv) D3 has a distinct time frame from other lipid mediators, appearing late in the resolution phase.
Dalli, Jesmond +7 more
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The therapeutic potential of resolvins in pulmonary diseases [PDF]
, 2023 Uncontrolled inflammation leads to nonspecific destruction and remodeling of tissues and can contribute to many human pathologies, including pulmonary diseases.
Henricks, Paul A J +2 more
core
Bioactive lipid-based therapeutic approach to COVID-19 and other similar infections
Archives of Medical Science, 2021 COVID-19 is caused by SARS-CoV-2 infection. Epithelial and T, NK, and other immunocytes release bioactive lipids especially arachidonic acid (AA) in response to microbial infections to inactivate them and upregulate the immune system.
Undurti N. Das
doaj +1 more source
Journal of Lipid Research, 2013 Placental inflammation is associated with several pregnancy disorders. Inflammation is limited by anti-inflammatory and proresolving mechanisms, the latter partly mediated by resolvins and protectins derived from omega-3 polyunsaturated fatty acids (n ...
Megan L. Jones +6 more
doaj +1 more source
Resolvin D1 and Resolvin D5 Lower Antibiotic Doses in Infection
The FASEB Journal, 2013 Underlying mechanisms for how bacterial infections contribute to active resolution of acute inflammation are unknown. Here, we carried out LM‐metabololipidomics following Escherichia coli (E. coli) infections in mice for temporal identification of pro‐inflammatory (prostaglandins and ...
Nan Chiang +3 more
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Protectin and resolvin gut inflammation [PDF]
Science, 2017 Inflammation Even when laced with syrup, cod-liver oil is disgusting, but it is an important source of omega-3-docosapentaenoic fatty acid (DPA). After being swallowed, DPA is converted into specialized proresolving lipid mediators (SPMs), including protectin and resolvin.
openaire +2 more sources
Major structure-activity relationships of resolvins, protectins, maresins and their analogues
, 2023 Resolvins, protectins and maresins are a series of polyunsaturated fatty acid-derived molecules which play important roles in the resolution of inflammation.
O'Sullivan, Killian +2 more
core +1 more source
MetabolitesAcute inflammation is the body’s first defense in response to pathogens or injury that is partially governed by a novel genus of endogenous lipid mediators that orchestrate the resolution of inflammation, coined specialized pro-resolving mediators (SPMs).
Muhammad Usman Babar +10 more
doaj +1 more source
Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses [PDF]
The Journal of Immunology, 2012 Abstract Asthma is a disease of airway inflammation that in most cases fails to resolve. The resolution of inflammation is an active process governed by specific chemical mediators, including D-series resolvins. In this study, we determined the impact of resolvin D1 (RvD1) and aspirin-triggered RvD1 (AT-RvD1) on the development of ...
Alexandre P, Rogerio +9 more
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Frontiers in Immunology, 2023 Sjögren’s syndrome is a chronic inflammatory autoimmune disease characterized by diminished secretory function of the exocrine glands. Although extensive investigation has been done to understand Sjögren’s syndrome, the causes of the disease are as yet ...
Harim T. dos Santos +11 more
doaj +1 more source