Results 1 to 10 of about 2,986 (128)
BiomoleculesPolyunsaturated fatty acids (PUFAs), particularly omega-3 derivatives such as docosahexaenoic acid (DHA), are precursors of specialized pro-resolving mediators (SPMs) that actively orchestrate the resolution of inflammation.
Daniel R Gonzalez, Jessica Zuniga
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Molecules, 2022 Marine organisms are an important source of natural products with unique and diverse chemical structures that may hold the key for the development of novel drugs.
Narcisa Bandarra +2 more
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Protective Potential of Maresins in Cardiovascular Diseases
Frontiers in Cardiovascular Medicine, 2022 Cardiovascular diseases are the leading causes of global mortality. Growing evidence suggests that unresolved inflammation contributes to the chronicity, progression and morbidity of many cardiovascular diseases, thus emphasizing the urgent need to ...
Lihong Chen, Chen Lihong
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Resolving Inflammation in CKD: The Potential of SPMs and Omega-3 Derivatives as Biomarkers and Therapeutics [PDF]
BiomedicinesChronic kidney disease (CKD) affects more than 10% of the population and is associated with a persistent, low-grade inflammatory state that accelerates tubulointerstitial fibrosis, worsens prognosis, and increases cardiovascular risk. This review aims to
Beata Franczyk +8 more
doaj +2 more sources
Antioxidants, 2022 Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig +2 more
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Mediators of Inflammation, 2018 Acute inflammatory responses are host-protective and normally self-limited; these responses can maintain cell homeostasis and promote defense against various infections and damage factors.
Yong Xu, Shi Tang, Yong Xu
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Maresins as novel anti-inflammatory actors and putative therapeutic targets in sepsis
Pharmacological ResearchSepsis, a complex clinical syndrome characterized by an exaggerated host response to infection, often necessitates hospitalization and intensive care unit admission. Delayed or inaccurate diagnosis of sepsis, coupled with suboptimal treatment strategies,
Yun Lin
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Macrophages: their role in immunity and their relationship with fatty acids in health and disease [PDF]
Frontiers in ImmunologyThe intricate interplay between macrophage biology and lipid metabolism has emerged as a critical determinant of metabolic homeostasis, disease progression and pathogenesis.
Mayte Rueda-Munguía +9 more
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The potential role of n-3 fatty acids and their lipid mediators on asthmatic airway inflammation [PDF]
Frontiers in ImmunologyAsthma, is a common, significant and diverse condition marked by persistent airway inflammation, with a major impact on human health worldwide. The predisposing factors for asthma are complex and widespread.
Yuan Tian +3 more
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Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source