Results 1 to 10 of about 2,126 (153)

Subfatin, Asprosin, Alamandine and Maresin-1 Inflammation Molecules in Cardiopulmonary Bypass

Journal of Inflammation Research, 2023
Onur Hanbeyoglu,1 Suna Aydin2– 4 1Department of Anesthesiology, Fethi Sekin City Hospital, Elazig, Turkiye; 2Department of Cardiovascular Surgery, Fethi Sekin City Hospital, Elazig, Turkiye; 3Department of Anatomy, School of Medicine, Firat University ...
Hanbeyoglu O, Aydin S
doaj   +1 more source

Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]

Mediators of Inflammation, 2016
Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models ...
Ruidong Li, Yaxin Wang, Zhijun Ma, Muyuan Ma, Di Wang, Gengchen Xie, Yuping Yin, Peng Zhang, Kaixiong Tao   +8 more
doaj   +2 more sources

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

The Protective Effects of Maresin 1 in the OVA-Induced Asthma Mouse Model

Mediators of Inflammation, 2021
Asthma is a chronic inflammatory disease that cannot be cured. Maresin 1 (MaR1) is a specific lipid synthesized by macrophages that exhibits powerful anti-inflammatory effects in various inflammatory diseases.
Guochun Ou, Qin Liu, Chengxiu Yu, Xiaoju Chen, Wenbo Zhang, Yong Chen, Tao Wang, Yongqiang Luo, Guolu Jiang, Mingmei Zhu, Hongmei Li, Mei Zeng   +11 more
doaj   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed, Abdinasir Adam Shidane, Abdullahi Mohamud Abdiasis, Mohamed Hassan Hussein, Ayaanle Osman Ibrahim, Anas Ali Abdi, Kowthar Ismail Hashi, Mohamed Abdullahi Mohamud, Ali Jimale Mohamed   +8 more
wiley   +1 more source

Omega Fatty Acids in Hair Loss Disorders: A Scoping Review of Preclinical and Clinical Evidence

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Omega fatty acids, including polyunsaturated omega‐3 and omega‐6 fatty acids (PUFAs) and monounsaturated omega‐9 fatty acids, regulate inflammation, cellular signaling, and tissue homeostasis, and may influence hair follicle biology and hair growth.
Nana‐Hawwa Abdul‐Rahman, Jacqueline D. Wang, Miriam Motlak, Gerardo Guiltarte, Reethi S. Padmanabhan, Ellen T. Lee, Sonal Choudhary   +6 more
wiley   +1 more source

Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3. [PDF]

PLoS ONE, 2016
Maresin conjugates in tissue regeneration (MCTR) are a new family of evolutionarily conserved chemical signals that orchestrate host responses to promote tissue regeneration and resolution of infections.
Jesmond Dalli, Julia M Sanger, Ana R Rodriguez, Nan Chiang, Bernd W Spur, Charles N Serhan   +5 more
doaj   +1 more source

Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT‐qPCR Validation

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Step I: Screened HR/SMYD4 as key keloid epigenetic genes via bulk/scRNA‐seq and machine learning. Step II: Built a high‐performance nomogram (AUC = 0.988). Step III: Conducted multi‐omics analyses. Step IV: Experimentally verified their differential expression and pathogenic roles.
Yifei Wang, Shuqian Dou, Mingkun Dai, Guoxun Yang, Wenjun Liu   +4 more
wiley   +1 more source

Fatty Acid Signatures as Nutritional Indices: Molecular Gateways to Health, Aging, and Functional Food Innovation

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Systems framework linking dietary fatty acids with the functional lipidome, health, and precision nutrition. Dietary fatty acids from plant‐based, marine, and animal sources undergo absorption, endogenous desaturation and elongation, oxidation, and tissue‐specific incorporation and remodeling, generating individualized FA signatures.
Mohammad Nazrul Islam Bhuiyan, Md. Selim Reza, Farzana Mim   +2 more
wiley   +1 more source

Macrophage: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun, Linqing Wen, Shiyun Tang, Lu Liu, Nianzhi Chen   +4 more
wiley   +1 more source