Results 31 to 40 of about 2,016 (189)
Circulating Maresin-1 and cartilage remodeling biomarkers in rheumatoid arthritis and osteoarthritis [PDF]
Scientific ReportsRheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic joint diseases characterized by persistent inflammation, progressive cartilage degeneration, and impaired tissue repair mechanisms.
Omer Esmez +5 more
doaj +2 more sources
Maresin 1 induces resolution of hepatic fibrosis through RORα-dependent reprogramming of resident macrophages [PDF]
Frontiers in PharmacologyHepatic fibrosis is a progressive pathological condition characterized by chronic inflammation and excessive extracellular matrix deposition (ECM), which may progress to cirrhosis and liver failure. Although specialized pro-resolving lipid mediators have
Francisca Herrera Vielma +13 more
doaj +2 more sources
Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer [PDF]
Mediators of Inflammation, 2020 Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods.
Tian Miao +9 more
doaj +3 more sources
Drug Design, Development and Therapy, 2019 Yun Qiu, Yichen Wu, Hongmei Zhao, Hong Sun, Sumin Gao Department of Emergency Medicine, The Affiliated Huaian No 1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu Province, China Background: Inflammation and oxidative ...
Qiu Y, Wu Y, Zhao H, Sun H, Gao S
doaj +1 more source
Identification and Actions of a Novel Third Maresin Conjugate in Tissue Regeneration: MCTR3. [PDF]
PLoS ONE, 2016 Maresin conjugates in tissue regeneration (MCTR) are a new family of evolutionarily conserved chemical signals that orchestrate host responses to promote tissue regeneration and resolution of infections.
Jesmond Dalli +5 more
doaj +3 more sources
Maresin‐1 ameliorates hypertensive vascular remodeling through its receptor LGR6
MedCommHypertensive vascular remodeling is defined as the changes in vascular function and structure induced by persistent hypertension. Maresin‐1 (MaR1), one of metabolites from Omega‐3 fatty acids, has been reported to promote inflammation resolution in ...
Zheng Yin +12 more
doaj +2 more sources
Maresins: The Mainstay in Periodontal Resolution [PDF]
Cureus, 2022 Not much was known about the resolution of inflammation until the recent past when significant breakthroughs led to the unveiling of the exact mechanism of this. It is now known that the resolution of inflammation involves specific mediators of resolution such as lipoxins, protectins, resolvins, and maresins, making it an active process.
Gireddy, Hima Bindu +5 more
openaire +2 more sources
Synthesis of Optically Active Maresin 2 and Maresin 2n-3 DPA [PDF]
Synlett, 2020 AbstractMaresins are among the most potent antiinflammatory lipid metabolites. We report stereoselective syntheses of maresin 2 and maresin 2n-3 DPA. The anti-diol was constructed through epoxide ring opening of an optically active β,γ-epoxy aldehyde, synthesized in situ by Swern oxidation of the corresponding alcohol.
Narihito Ogawa +2 more
openaire +1 more source
Frontiers in Psychiatry, 2023 BackgroundInflammation and immune activation may play a role in the pathological mechanism of Major Depressive Disorder (MDD). Evidence from cross-sectional and longitudinal studies of adolescents and adults has shown that MDD is associated with ...
Tian Qiu +11 more
doaj +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source