Protective Potential of Maresins in Cardiovascular Diseases
Frontiers in Cardiovascular Medicine, 2022 Cardiovascular diseases are the leading causes of global mortality. Growing evidence suggests that unresolved inflammation contributes to the chronicity, progression and morbidity of many cardiovascular diseases, thus emphasizing the urgent need to ...
Min Liu, Huixiang He, Lihong Chen
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Maresin 1 Inhibits TRPV1 in Temporomandibular Joint-Related Trigeminal Nociceptive Neurons and TMJ Inflammation-Induced Synaptic Plasticity in the Trigeminal Nucleus [PDF]
Mediators of Inflammation, 2015 In the trigeminal system, disruption of acute resolution processing may lead to uncontrolled inflammation and chronic pain associated with the temporomandibular joint (TMJ). Currently, there are no effective treatments for TMJ pain. Recently, it has been
Chul-Kyu Park
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Maresin 1 repletion improves muscle regeneration after volumetric muscle loss [PDF]
eLife, 2023 The acute traumatic or surgical loss of skeletal muscle, known as volumetric muscle loss (VML), is a devastating type of injury that results in exacerbated and persistent inflammation followed by fibrosis.
Jesus A Castor-Macias +12 more
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Serum biomarker screening and metabolic profiling analysis of nonalcoholic fatty liver disease patients using untargeted metabolomics and machine learning techniques [PDF]
Frontiers in Molecular BiosciencesBackground and ObjectiveNon-alcoholic fatty liver disease (NAFLD) represents the most prevalent chronic hepatic metabolic disorder globally. Without timely intervention, it can progress to non-alcoholic steatohepatitis (NASH), liver fibrosis, and even ...
Lijuan Dan +11 more
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Maresin 1 alleviates myocardial ischemia-reperfusion injury in rats by suppressing inflammation [PDF]
European Journal of HistochemistryMyocardial ischemia-reperfusion injury (MIRI) induces severe inflammatory damage to cardiac tissue, leading to structural impairment and functional decline.
Hongkai Xiao +5 more
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Subfatin, Asprosin, Alamandine and Maresin-1 Inflammation Molecules in Cardiopulmonary Bypass
Journal of Inflammation Research, 2023 Onur Hanbeyoglu,1 Suna Aydin2– 4 1Department of Anesthesiology, Fethi Sekin City Hospital, Elazig, Turkiye; 2Department of Cardiovascular Surgery, Fethi Sekin City Hospital, Elazig, Turkiye; 3Department of Anatomy, School of Medicine, Firat University ...
Hanbeyoglu O, Aydin S
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Maresin-1 suppresses imiquimod-induced skin inflammation by regulating IL-23 receptor expression
Scientific Reports, 2018 The anti-inflammatory effect of omega 3 polyunsaturated fatty acids has been confirmed in various inflammatory disease models. Maresin-1 (MaR1) is a lipid mediator derived from the omega-3 fatty acid docosahexaenoic acid (DHA) that has displayed strong ...
Natsuko Saito-Sasaki +8 more
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Maresin-1 Ameliorates Chronic Unpredictable Stress-Induced Depressive-like Behaviors Associated with Dynamic Modulation of Hippocampal Microglial Activity and TSPO PET Signals [PDF]
BiomedicinesBackground/Objectives: Maresin-1 (MaR1), a specialized pro-resolving mediator (SPM) derived from omega-3 fatty acids, has demonstrated potent anti-inflammatory and pro-resolving properties.
Anhai Zheng +7 more
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Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis [PDF]
Journal of Neuroinflammation, 2022 Background Resolution of inflammation is an active and regulated process that leads to the clearance of cell debris and immune cells from the challenged tissue, facilitating the recovery of homeostasis.
Alba Sánchez-Fernández +6 more
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Plasma and aqueous humor levels of Maresin-1 in patients with diabetic retinopathy [PDF]
Scientific ReportsThe aim of this study was to evaluate plasma and aqueous Maresin-1 (MaR1) levels in patients with diabetic retinopathy (DR) and to examine the ability of these levels to distinguish proliferative diabetic retinopathy.
Sabiha Güngör Kobat +8 more
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