Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages. [PDF]
PLoS ONE, 2014 Maresins are a new family of anti-inflammatory and pro-resolving lipid mediators biosynthesized from docosahexaenoic acid (DHA) by macrophages. Here we identified a novel pro-resolving product, 13R,14S-dihydroxy-docosahexaenoic acid (13R,14S-diHDHA ...
Bin Deng +6 more
doaj +8 more sources
Effect of Thyroxine Replacement Therapy on Serum Maresin 1 and NF-kB Levels in Patients with Hashimoto Thyroiditis [PDF]
DiagnosticsBackground/Objectives: This study aimed to investigate the effects of thyroxine replacement therapy (TRT) on serum Maresin 1 and nuclear factor kappa beta (NF-kB) levels in patients with Hashimoto’s thyroiditis (HT).
Meltem Yardim +3 more
doaj +3 more sources
The Protective Effects of Maresin 1 in the OVA-Induced Asthma Mouse Model [PDF]
Mediators of Inflammation, 2021 Asthma is a chronic inflammatory disease that cannot be cured. Maresin 1 (MaR1) is a specific lipid synthesized by macrophages that exhibits powerful anti-inflammatory effects in various inflammatory diseases.
Guochun Ou +11 more
doaj +4 more sources
Maresin 1 Alleviates Seizure Symptoms by Modulating the Crosstalk Between Inflammation and Ferroptosis [PDF]
Journal of Inflammation ResearchYueying Liu,1,* Shengjie Xu,1,* Yufan Luo,1,* Xue Xiao,1 Xiaofan Jiang,1 Wei Xiao,1 Ruijin Xie,1 Xianhui Deng,2 Zhen Li,3 Yingsi Cao,1 Yuanjin Chang,1 Dongqin Wu,1 Hua Xu,1 Wenjing Zhao4 1Department of Pediatrics, Affiliated ...
Liu Y +13 more
doaj +4 more sources
Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]
Mediators of Inflammation, 2016 Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models ...
Ruidong Li +8 more
doaj +4 more sources
BMC Ophthalmology, 2023 Background Maresin-1 plays an important role in diabetic illnesses and ferroptosis is associated with pathogenic processes of diabetic retinopathy (DR).
Yufei Li, Jieyu Liu, Xibo Ma, Xue Bai
doaj +2 more sources
Frontiers in Medicine, 2022 Background: Maresin 1 plays a role in the regulation of inflammation and metabolic diseases in vivo. An increasing number of studies have reported that postmenopausal osteoporosis (PMOP) is associated with inflammation.
Fang-Yuan Teng, Yong Xu
exaly +3 more sources
12‑weeks fisetin supplementation and interval resistance with aerobic training: changes in Maresin‑1 and inflammatory markers in men with obesity: a randomized controlled trial [PDF]
Journal of the International Society of Sports NutritionBackground Obesity is characterized by low‑grade chronic inflammation and impaired insulin sensitivity. Maresin‑1 (MaR1), a specialized pro‑resolving mediator, plays a critical role in terminating inflammation and supporting metabolic homeostasis ...
Mehran Alipour +4 more
doaj +2 more sources
Maresin-1 impairs cutaneous wound healing response [PDF]
ImmunoHorizonsAbstract Maresin-1 is a derivative of docosahexaenoic acid with strong anti-inflammatory action in various disease models. However, these effects may not always be beneficial. In instances like cutaneous diseases in which wound healing is important, inflammation is required.
Natsuko Saito-Sasaki +2 more
exaly +4 more sources
Maresin 1 Mitigates High Glucose-Induced Mouse Glomerular Mesangial Cell Injury by Inhibiting Inflammation and Fibrosis [PDF]
Mediators of Inflammation, 2017 Background. Inflammation and fibrosis are the important pathophysiologic processes in diabetic nephropathy (DN). Maresin 1 is a potential anti-inflammatory lipid mediator, which has displayed powerful proresolving activities. Aim.
Shi Tang +7 more
doaj +2 more sources