Results 1 to 10 of about 6,206 (204)
Lipoxins as Modulators of Diseases [PDF]
CellsLipoxins were discovered 40 years ago, and since then, their beneficial roles for human health have been confirmed in numerous studies. These small molecules belong to the eicosanoid class of compounds, which are generated metabolically by lipoxygenases.
Uzma Saqib +18 more
doaj +5 more sources
Lipoxin and Aspirin-Triggered Lipoxins [PDF]
The Scientific World Journal, 2010 Lipoxins and their 15 epimers, aspirin triggered lipoxins (ATL), are eicosanoids derived from sequential lipoxygenase (LO) metabolism of arachidonic acid.
Mario Romano
doaj +5 more sources
Scientific World Journal, The, 2002 It is well appreciated that lipid-derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved.
Charles N Serhan +2 more
exaly +3 more sources
Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins [PDF]
Brazilian Journal of Medical and Biological Research, 2001 Multicellular host responses to infection, injury or inflammatory stimuli lead to the formation of a broad range of chemical mediators by the host. The integrated response of the host is essential to health and disease; thus it is important to achieve a ...
Fierro I.M., Serhan C.N.
doaj +7 more sources
Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures [PDF]
iScience, 2022 Summary: Adipose tissue inflammation drives obesity-related cardiometabolic diseases. Enhancing endogenous resolution mechanisms through administration of lipoxin A4, a specialized pro-resolving lipid mediator, was shown to reduce adipose inflammation ...
Matúš Soták +19 more
doaj +2 more sources
Lipoxins: regulators of resolution [PDF]
Current Opinion in Pharmacology, 2010 Persistent inflammation underlies many prevalent diseases including atherosclerosis and diabetes. There is a growing appreciation that inflammation and its active resolution may be modulated by endogenously produced lipids. Pre-eminent amongst these mediators are lipoxin [LX]A4 and LXB4.
Ryan, Aidan, Godson, Catherine
openaire +6 more sources
Lipoxins and aspirin-triggered lipoxins in resolution of inflammation
European Journal of Pharmacology, 2015 The resolution of the inflammatory response is highly regulated by the timely biosynthesis of a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers, aspirin triggered lipoxins (ATL) derived by the lipoxygenase (LO) route of arachidonic acid metabolism. In particular, they are formed and released by cells expressing 5-,
ROMANO, Mario +3 more
openaire +4 more sources
Lipoxins: A Novel Regulator in Embryo Implantation [PDF]
The Scientific World Journal, 2011 Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity ...
Jing Xiong, Pan Zeng, Duyun Ye
doaj +2 more sources
Lipoxins as biomarkers of lupus and other inflammatory conditions [PDF]
Lipids in Health and Disease, 2011 Inflammatory events persist in systemic lupus erythematosus (lupus) despite the use of anti-inflammatory (both steroidal and non-steroidal) and immunosuppressive drugs leading to delay in the healing/repair process and so tissue/organ damage continues ...
Das Undurti N
doaj +2 more sources
Resolving Inflammation in CKD: The Potential of SPMs and Omega-3 Derivatives as Biomarkers and Therapeutics [PDF]
BiomedicinesChronic kidney disease (CKD) affects more than 10% of the population and is associated with a persistent, low-grade inflammatory state that accelerates tubulointerstitial fibrosis, worsens prognosis, and increases cardiovascular risk. This review aims to
Beata Franczyk +8 more
doaj +2 more sources