Results 21 to 30 of about 261 (130)
Lipoxins: resolutionary road [PDF]
British Journal of Pharmacology, 2009 The resolution of inflammation is an active process controlled by endogenous mediators with selective actions on neutrophils and monocytes. The initial phase of the acute inflammatory response is characterized by the production of pro‐inflammatory mediators followed by a second phase in which lipid mediators with pro‐resolution activities may be ...
Paola, Maderna, Catherine, Godson
openaire +2 more sources
Specialized Pro-Resolving Mediators Reduce Scarring After Cleft Lip Repair
Frontiers in Immunology, 2022 ObjectiveResidual scarring after cleft lip repair surgery remains a challenge for both surgeons and patients and novel therapeutics are critically needed. The objective of this preclinical experimental study was to evaluate the impact of the methyl-ester
Evangelos Papathanasiou +11 more
doaj +1 more source
Frontiers in Immunology, 2020 G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of ...
Patricia R. Souza +8 more
doaj +1 more source
Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing [PDF]
The Journal of Experimental Medicine, 2007 Inflammatory conditions can lead to debilitating and persistent pain. This hyperalgesia reflects sensitization of peripheral terminals and facilitation of pain signaling at the spinal level. Studies of peripheral systems show that tissue injury triggers not only inflammation but also a well-orchestrated series of events that leads to reversal of the ...
Svensson, Camilla +2 more
openaire +4 more sources
Frontiers in Immunology, 2020 Eicosanoids modulate both innate and adaptive immune responses in Mycobacterium tuberculosis (Mtb) infection and have been suggested as possible Host Directed Therapy (HDT) targets, but more knowledge of eicosanoid dynamics in Mtb infection is required ...
Kristin Grotle Nore +7 more
doaj +1 more source
Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases
Frontiers in Immunology, 2021 Inflammation is an a physiological response instead an essential response of the organism to injury and its adequate resolution is essential to restore homeostasis.
Rafael I. Jaén +9 more
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Frontiers in Microbiology, 2018 Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas.
Rodrigo A. López-Muñoz +7 more
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Frontiers in Immunology, 2020 Obesity is a major independent risk factor for increased morbidity and mortality upon infection with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which is responsible for the current coronavirus disease pandemic (COVID-19).
Anandita Pal +4 more
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Frontiers in ImmunologyThe core pathology of asthma involves not only inflammation amplification but also a systemic failure of inflammation resolution programs. This review first summarizes the Specialized Pro-resolving Mediators (SPM) family, efferocytosis, and their ...
Bingxue Zhang +10 more
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Lipoxins: A Novel Regulator in Embryo Implantation
The Scientific World Journal, 2011 Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity ...
Jing Xiong, Pan Zeng, Duyun Ye
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