Results 41 to 50 of about 6,206 (204)

Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis

, 2022
Dysregulated chronic inflammation plays a crucial role in the pathophysiology of atherosclerosis and may be a result of impaired resolution. Thus, restoring levels of specialized pro-resolving mediators (SPMs) to promote the resolution of inflammation ...
Rani, A, Borgeson, E, Dalli, Jesmond, Nyström, S., Clark, M, Skoog, Per, Bromberg, Jonathan, Dalli, J., Blomgran, R, Dalli, J, Nystrom, S, Quiding-Jarbrink, M, Rajan, Meenu Rohini, Quiding-Järbrink, Marianne,, Skoog, Per,, Sotak, Matus,, Skoog, P, Quiding-Järbrink, Marianne, Dalli, Jesmond,, Kraft, Jamie D.,, Blomgran, Robert,, Nyström, Sofia N.,, Kraft, JD, Bergström, I., Clark, Madison,, Rani, Alankrita,, Rajan, Meenu Rohini,, Kraft, Jamie D., Sotak, Matus, Nyström, Sofia, Blomgran, Robert, Bergstrom, I, Quiding‐Järbrink, Marianne, Bergström, Ida,, Bromberg, J., Börgeson, Emma, Börgeson, Emma,, Sotak, M, Bromberg, J, Rani, Alankrita, Clark, Madison, Nyström, Sofia N., Rajan, MR, Blomgran, R., Rohin Rajan, Meenu,, Bergström, Ida, Bromberg, Jonathan,   +46 more
core   +1 more source

Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control

Frontiers in Microbiology, 2018
Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas.
Rodrigo A. López-Muñoz, Alfredo Molina-Berríos, Carolina Campos-Estrada, Carolina Campos-Estrada, Patricio Abarca-Sanhueza, Luis Urrutia-Llancaqueo, Miguel Peña-Espinoza, Juan D. Maya   +7 more
doaj   +1 more source

Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 Infection

Frontiers in Immunology, 2020
Obesity is a major independent risk factor for increased morbidity and mortality upon infection with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which is responsible for the current coronavirus disease pandemic (COVID-19).
Anandita Pal, Kymberly M. Gowdy, Kenneth J. Oestreich, Melinda Beck, Saame Raza Shaikh   +4 more
doaj   +1 more source

Comparison of effectiveness of low-dose aspirin versus omega-3 fatty acids as adjuvants to nonsurgical periodontal therapy in Type II diabetic patients with chronic periodontitis

Journal of Indian Society of Periodontology, 2019
Context: Periodontitis and diabetes are universally prevalent diseases which are interlinked with each other. Inflammatory products released both by the microorganisms, and the host plays a pivotal role in causing both the diseases.
Prathyusha Rampally, Rekha Rani Koduganti, Sastri Nadiminty Ganapathi, Veerendranath Reddy Panthula, Prasanna Jammula Surya   +4 more
doaj   +1 more source

Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications

Frontiers in Pharmacology, 2018
Diabetes and its associated chronic complications present a healthcare challenge on a global scale. Despite improvements in the management of chronic complications of the micro-/macro-vasculature, their growing prevalence and incidence highlights the ...
Monica de Gaetano, Caitriona McEvoy, Caitriona McEvoy, Darrell Andrews, Antonino Cacace, Jonathan Hunter, Eoin Brennan, Catherine Godson   +7 more
doaj   +1 more source

Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release. [PDF]

PLoS ONE, 2013
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain ...
Sally Abdelmoaty, Gustaf Wigerblad, Duygu B Bas, Simone Codeluppi, Teresa Fernandez-Zafra, El-Sayed El-Awady, Yasser Moustafa, Alaa El-Din S Abdelhamid, Ernst Brodin, Camilla I Svensson   +9 more
doaj   +1 more source

Lipoxins, Aspirin-Triggered Epi-Lipoxins, Lipoxin Stable Analogues, and the Resolution of Inflammation [PDF]

Journal of the American Society of Nephrology, 2002
Lipoxins (LX) are eicosanoids with antiinflammatory activity in glomerulonephritis (GN) and inflammatory diseases, hypersensitivity, and ischemia reperfusion injury. It has been demonstrated that LXA(4) stimulates non-phlogistic phagocytosis of apoptotic polymorphonuclear neutrophils (PMN) by monocyte-derived macrophages (Mphi) in vitro, suggesting a ...
Siobhan, Mitchell, Graham, Thomas, Killeen, Harvey, David, Cottell, Keira, Reville, Giovanni, Berlasconi, Nicos A, Petasis, Lars, Erwig, Andrew J, Rees, John, Savill, Hugh R, Brady, Catherine, Godson   +11 more
openaire   +2 more sources

Resolving Lipids: Lipoxins Regulate Reverse Cholesterol Transport

, 2014
Disruptions in cholesterol homeostasis contribute to cardiovascular disease (CVD). In a recent issue of Cell Metabolism, Demetz et al. (2014) report that endogenous lipoxygenase-mediated metabolism of another lipid, arachidonic acid, produces lipoxins ...
Spite, Matthew
core   +1 more source

Endogenous inhibitory mechanisms in asthma

Journal of Allergy and Clinical Immunology: Global, 2023
Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E2, prostaglandin I2 ...
Sergio E. Chiarella, MD, Peter J. Barnes, MD   +1 more
doaj   +1 more source

Therapeutic Effects of Specialized Pro-Resolving Lipids Mediators on Cardiac Fibrosis via NRF2 Activation

Antioxidants, 2020
Heart disease is the number one mortality disease in the world. In particular, cardiac fibrosis is considered as a major factor causing myocardial infarction and heart failure. In particular, oxidative stress is a major cause of heart fibrosis.
Gyeoung Jin Kang, Eun Ji Kim, Chang Hoon Lee   +2 more
doaj   +1 more source