Results 61 to 70 of about 5,766 (133)

Phospholipid derived mediators and glomerulonephritis

Mediators of Inflammation, 1993
The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists.
E. N. Wardle
doaj   +1 more source

Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus?

Lipids in Health and Disease, 2011
Acetylcholine, the principal vagus neurotransmitter, inhibits inflammation by suppressing the production of pro-inflammatory cytokines through a mechanism dependent on the α7 nicotinic acetylcholine receptor subunit (alpha7nAChR) that explains why vagus ...
Das Undurti N
doaj   +1 more source

Can essential fatty acids reduce the burden of disease(s)?

Lipids in Health and Disease, 2008
Coronary heart disease, stroke, diabetes mellitus, hypertension, cancer, depression schizophrenia, Alzheimer's disease, and collagen vascular diseases are low-grade systemic inflammatory conditions that are a severe burden on health care resources ...
Das Undurti N
doaj   +1 more source

Molecular Circuits of Resolution in Renal Disease

The Scientific World Journal, 2010
Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting
Emma Börgeson, Catherine Godson
doaj   +1 more source

Beneficial role of bioactive lipids in the pathobiology, prevention, and management of HBV, HCV and alcoholic hepatitis, NAFLD, and liver cirrhosis: A review

Journal of Advanced Research, 2019
It has been suggested that hepatitis B virus (HBV)- and hepatitis C virus (HCV)-induced hepatic damage and cirrhosis and associated hypoalbuminemia, non-alcoholic fatty liver disease (NAFLD), and alcoholic fatty liver disease (AFLD) are due to an ...
Undurti N. Das
doaj   +1 more source

Mechanisms in anti-inflammation and resolution: the role of lipoxins and aspirin-triggered lipoxins

Brazilian Journal of Medical and Biological Research, 2001
Multicellular host responses to infection, injury or inflammatory stimuli lead to the formation of a broad range of chemical mediators by the host. The integrated response of the host is essential to health and disease; thus it is important to achieve a ...
Fierro I.M., Serhan C.N.
doaj  

Advances in the Chemistry and Biology of Specialised Pro-Resolving Mediators (SPMs)

Molecules
This review article assembles key recent advances in the synthetic chemistry and biology of specialised pro-resolving mediators (SPMs). The major medicinal chemistry developments in the design, synthesis and biological evaluation of synthetic SPM ...
Lucy Byrne, Patrick J. Guiry
doaj   +1 more source

Utilization of lipoxins and other specialised pro-resolving mediators in the prevention and treatment of diabetic nephropathy and diabetic cardiovascular disease

Acta Marisiensis - Seria Medica
Diabetes mellitus type 2 is a chronic disease caused by insulin resistance. Whilst first originating in the adipose tissue, this pathophysiological process later affects the muscles and the liver as well.
Bergo Ivan, Pastorello Ylenia
doaj   +1 more source

Lipoxins A4 and B4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation

Journal of Neuroinflammation
Lipoxins are small lipids that are potent endogenous mediators of systemic inflammation resolution in a variety of diseases. We previously reported that Lipoxins A4 and B4 (LXA4 and LXB4) have protective activities against neurodegenerative injury.
Izhar Livne-Bar, Shubham Maurya, Karsten Gronert, Jeremy M. Sivak   +3 more
doaj   +1 more source

P2X receptors and lipids interact to modulate inflammation. [PDF]

J Lipid Res
Vidal VN, Pereira TC, Teixeira GP, Rocha L, Faria RX.   +4 more
europepmc   +1 more source