Results 81 to 90 of about 6,206 (204)
Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 3, July/September 2026.Abstract INTRODUCTION Sphingosine kinase 1 (SPHK1) has been implicated in the regulation of pro‐resolving lipid mediators relevant to neuroinflammation in Alzheimer's disease (AD). However, no studies have evaluated the genetic association between SPHK1 polymorphisms and AD susceptibility.
Dong‐Ju Kim +2 more
wiley +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
iNew Medicine, Volume 2, Issue 2, June 2026.The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
Lipids in Health and Disease, 2010 The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue concentrations of polyunsaturated fatty acids ...
Das Undurti N
doaj +1 more source
Phospholipid derived mediators and glomerulonephritis
Mediators of Inflammation, 1993 The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists.
E. N. Wardle
doaj +1 more source
Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus?
Lipids in Health and Disease, 2011 Acetylcholine, the principal vagus neurotransmitter, inhibits inflammation by suppressing the production of pro-inflammatory cytokines through a mechanism dependent on the α7 nicotinic acetylcholine receptor subunit (alpha7nAChR) that explains why vagus ...
Das Undurti N
doaj +1 more source
, 1986 The existence of a 15(S)-hydroxy-5,6-oxido-7,9,13-trans 11-cis-eicosatetraenoic acid intermediate in the biosyntheses of lipoxins A and B has recently been proposed.
Webber, Stephen E. +11 more
core +1 more source
Lipoxina A4 na dor neuropática após a lesão medular: modulação da neuroinflamação e ativação microglial [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2015.A dor crônica está presente na maioria dos pacientes após a lesão medular traumática (LMT).
Martini, Alessandra Cadete
core
Journal of Advanced Research, 2019 It has been suggested that hepatitis B virus (HBV)- and hepatitis C virus (HCV)-induced hepatic damage and cirrhosis and associated hypoalbuminemia, non-alcoholic fatty liver disease (NAFLD), and alcoholic fatty liver disease (AFLD) are due to an ...
Undurti N. Das
doaj +1 more source
Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury [PDF]
, 2017 Astrocytes perform critical non-cell autonomous roles following CNS injury that involve either neurotoxic or neuroprotective effects. Yet the nature of potential prosurvival cues has remained unclear.
Won, Gah-Jone +17 more
core +1 more source
Molecular Circuits of Resolution in Renal Disease
The Scientific World Journal, 2010 Inflammation is a common feature of renal pathology. Lipid mediators, such as lipoxins, resolvins, and protectins, can actively promote the resolution of inflammation by inhibiting polymorphonuclear cell infiltration to the site of inflammation, shifting
Emma Börgeson, Catherine Godson
doaj +1 more source