Results 91 to 100 of about 6,206 (204)

Can essential fatty acids reduce the burden of disease(s)?

open access: yesLipids in Health and Disease, 2008
Coronary heart disease, stroke, diabetes mellitus, hypertension, cancer, depression schizophrenia, Alzheimer's disease, and collagen vascular diseases are low-grade systemic inflammatory conditions that are a severe burden on health care resources ...
Das Undurti N
doaj   +1 more source

Papel dual da lipoxina A4, nas alterações inflamatórias e cardiovasculares na sepse: uma janela de oportunidade [PDF]

open access: yes, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013.A pneumonia é uma das principais causas de sepse, que por sua vez é a maior causa de morte nas ...
Sordi, Regina de
core  

Native and Aspirin-Triggered Lipoxins Control Innate Immunity by Inducing Proteasomal Degradation of TRAF6 [PDF]

open access: yes, 2008
Innate immune signaling is critical for the development of protective immunity. Such signaling is, perforce, tightly controlled. Lipoxins (LXs) are eicosanoid mediators that play key counterregulatory roles during infection.
Fabiana S. Machado   +17 more
core   +1 more source

Eicosanoids in carcinogenesis

open access: yes4 open, 2019
Inflammation is the body's reaction to pathogenic (biological or chemical) stimuli and covers a burgeoning list of compounds and pathways that act in concert to maintain the health of the organism.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines [PDF]

open access: yes, 2012
Background The neuroinflammatory responses in the spinal cord following bone cancer development have been shown to play an important role in cancer-induced bone pain (CIBP).
Mi Wen-Li   +19 more
core   +1 more source

Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins

open access: yes, 2017
Atherogenesis is an inflammatory process with leukocytes infiltrating the arterial intima. The lipoxygenase pathways play a role in leukocyte recruitment through the generation of two classes of arachidonic acid lipid mediators, the leukotrienes and the ...
Hersberger, Martin
core  

A Novel Injectable Hydrogel Incorporating Lipoxin for Treatment of Inflammation-mediated Bone Resorption

open access: yes, 2021
Increased inflammation can disturb bone homeostasis leading to increased osteoclastogenesis and bone resorption. Studies have demonstrated that specialized pro-resolving lipid mediators such as lipoxins, can counteract inflammation and reduce bone loss ...
Jamjoom, Faris Z.
core  

Lipoxin formation in human nasal polyps and bronchial tissue

open access: yes, 1990
Chopped human nasal polyps and bronchial tissue produced lipoxin A4 and isomers of lipoxins A4 and B4, but not lipoxin B4, after incubation with exogenous leukotriene A4.
Anders Änggård   +9 more
core   +1 more source

Evidence for lipoxin formation by bovine polymorphonuclear leukocytes via triple dioxygenation of arachidonic acid

open access: yes, 1988
Incubation of bovine polymorphonuclear leukocytes (PMNs) with arachidonic acid leads to the formation of four lipoxins. The same lipoxins are also formed upon incubation of bovine PMNs with 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, 5 ...
Klerks, J.P.M.   +17 more
core   +1 more source

Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1

open access: yes, 2013
Lipoxins, which are endogenously produced lipid mediators, promote the resolution of inflammation, and may inhibit fibrosis, suggesting a possible role in modulating renal disease.
Sadlier, Denise M   +16 more
core   +1 more source

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