Results 31 to 40 of about 6,206 (204)
Lipoxins: resolutionary road [PDF]
British Journal of Pharmacology, 2009 The resolution of inflammation is an active process controlled by endogenous mediators with selective actions on neutrophils and monocytes. The initial phase of the acute inflammatory response is characterized by the production of pro‐inflammatory mediators followed by a second phase in which lipid mediators with pro‐resolution activities may be ...
Paola, Maderna, Catherine, Godson
openaire +2 more sources
Novel biphasic role of lipoxinA4 on expression of cyclooxygenase-2 in lipopolysaccharide-stimulated lung fibroblasts [PDF]
, 2011 Fibroblasts are important to host defence and immunity, can also as initiators of inflammation as well. As the endogenous "braking signal", Lipoxins can regulate anti-inflammation and the resolution of inflammation.
Gao, F. +24 more
core +1 more source
Frontiers in Immunology, 2020 Asthma represents one of the leading chronic diseases worldwide and causes a high global burden of death and disability. In asthmatic patients, the exacerbation and chronification of the inflammatory response are often related to a failure in the ...
Daniella Bianchi Reis Insuela +5 more
doaj +1 more source
Immunomodulation of periodontitis with SPMs
Frontiers in Oral Health, 2023 Inflammation is a critical component in the pathophysiology of numerous disease processes, with most therapeutic modalities focusing on its inhibition in order to achieve treatment outcomes.
Vaibhav Sahni +2 more
doaj +1 more source
Specialized Pro-Resolving Mediators Reduce Scarring After Cleft Lip Repair
Frontiers in Immunology, 2022 ObjectiveResidual scarring after cleft lip repair surgery remains a challenge for both surgeons and patients and novel therapeutics are critically needed. The objective of this preclinical experimental study was to evaluate the impact of the methyl-ester
Evangelos Papathanasiou +11 more
doaj +1 more source
Lipoxins and aspirin-triggered lipoxin inhibit inflammatory pain processing [PDF]
The Journal of Experimental Medicine, 2007 Inflammatory conditions can lead to debilitating and persistent pain. This hyperalgesia reflects sensitization of peripheral terminals and facilitation of pain signaling at the spinal level. Studies of peripheral systems show that tissue injury triggers not only inflammation but also a well-orchestrated series of events that leads to reversal of the ...
Svensson, Camilla +2 more
openaire +4 more sources
Frontiers in Immunology, 2020 G-protein-coupled receptor 40 (GPR40) is known to play a role in the regulation of fatty acids, insulin secretion, and inflammation. However, the function of this receptor in human neutrophils, one of the first leukocytes to arrive at the site of ...
Patricia R. Souza +8 more
doaj +1 more source
Lipoxins in the Nervous System: Brighter Prospects for Neuroprotection
Frontiers in Pharmacology, 2022 Lipoxins (LXs) are generated from arachidonic acid and are involved in the resolution of inflammation and confer protection in a variety of pathological processes.
Jiayu Zhang +4 more
doaj +1 more source
Frontiers in Immunology, 2020 Eicosanoids modulate both innate and adaptive immune responses in Mycobacterium tuberculosis (Mtb) infection and have been suggested as possible Host Directed Therapy (HDT) targets, but more knowledge of eicosanoid dynamics in Mtb infection is required ...
Kristin Grotle Nore +7 more
doaj +1 more source