Results 31 to 40 of about 5,787 (177)

Inflammatory and Pro-resolving Lipids in Trypanosomatid Infections: A Key to Understanding Parasite Control

Frontiers in Microbiology, 2018
Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas.
Rodrigo A. López-Muñoz, Alfredo Molina-Berríos, Carolina Campos-Estrada, Carolina Campos-Estrada, Patricio Abarca-Sanhueza, Luis Urrutia-Llancaqueo, Miguel Peña-Espinoza, Juan D. Maya   +7 more
doaj   +1 more source

Integrated pro-resolving mechanisms: a new dimension for optimizing anti-inflammatory therapy in asthma – a review of impaired inflammation resolution in airway remodeling

Frontiers in Immunology
The core pathology of asthma involves not only inflammation amplification but also a systemic failure of inflammation resolution programs. This review first summarizes the Specialized Pro-resolving Mediators (SPM) family, efferocytosis, and their ...
Bingxue Zhang, Bingxue Zhang, Yan Xu, Yan Xu, Guihua Song, Guihua Song, Mengmeng Sun, Mengmeng Sun, Suping Yu, Suping Yu, Mingyue Ren   +10 more
doaj   +1 more source

Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 Infection

Frontiers in Immunology, 2020
Obesity is a major independent risk factor for increased morbidity and mortality upon infection with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), which is responsible for the current coronavirus disease pandemic (COVID-19).
Anandita Pal, Kymberly M. Gowdy, Kenneth J. Oestreich, Melinda Beck, Saame Raza Shaikh   +4 more
doaj   +1 more source

Lipoxins: A Novel Regulator in Embryo Implantation

The Scientific World Journal, 2011
Embryo implantation is essential for mammalian pregnancy, which involves intricate cross-talk between the blastocyst and the maternal endometrium. Recent advances have identified various molecules crucial to implantation and endometrial receptivity ...
Jing Xiong, Pan Zeng, Duyun Ye
doaj   +1 more source

Comparison of effectiveness of low-dose aspirin versus omega-3 fatty acids as adjuvants to nonsurgical periodontal therapy in Type II diabetic patients with chronic periodontitis

Journal of Indian Society of Periodontology, 2019
Context: Periodontitis and diabetes are universally prevalent diseases which are interlinked with each other. Inflammatory products released both by the microorganisms, and the host plays a pivotal role in causing both the diseases.
Prathyusha Rampally, Rekha Rani Koduganti, Sastri Nadiminty Ganapathi, Veerendranath Reddy Panthula, Prasanna Jammula Surya   +4 more
doaj   +1 more source

Lipoxins, Aspirin-Triggered Epi-Lipoxins, Lipoxin Stable Analogues, and the Resolution of Inflammation [PDF]

Journal of the American Society of Nephrology, 2002
Lipoxins (LX) are eicosanoids with antiinflammatory activity in glomerulonephritis (GN) and inflammatory diseases, hypersensitivity, and ischemia reperfusion injury. It has been demonstrated that LXA(4) stimulates non-phlogistic phagocytosis of apoptotic polymorphonuclear neutrophils (PMN) by monocyte-derived macrophages (Mphi) in vitro, suggesting a ...
Siobhan, Mitchell, Graham, Thomas, Killeen, Harvey, David, Cottell, Keira, Reville, Giovanni, Berlasconi, Nicos A, Petasis, Lars, Erwig, Andrew J, Rees, John, Savill, Hugh R, Brady, Catherine, Godson   +11 more
openaire   +2 more sources

Resolution of Inflammation after Skeletal Muscle Ischemia–Reperfusion Injury: A Focus on the Lipid Mediators Lipoxins, Resolvins, Protectins and Maresins

Antioxidants, 2022
Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig, Gaetan Lutzweiler, Margherita Giannini, Anne Lejay, Anne-Laure Charles, Alain Meyer, Bernard Geny   +6 more
doaj   +1 more source

In regards to lipoxins as lipid mediators for the resolution of inflammation using the example of asthma

Acta Biomedica Scientifica
Asthma is the most important medical and social problem of our time due to its widespread prevalence, chronic course and heterogeneity, which determines the complexity of  treating this disease.
O. Yu. Kytikova, T. P. Novgorodtseva, I. S. Kovalenko   +2 more
doaj   +1 more source

Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications

Frontiers in Pharmacology, 2018
Diabetes and its associated chronic complications present a healthcare challenge on a global scale. Despite improvements in the management of chronic complications of the micro-/macro-vasculature, their growing prevalence and incidence highlights the ...
Monica de Gaetano, Caitriona McEvoy, Caitriona McEvoy, Darrell Andrews, Antonino Cacace, Jonathan Hunter, Eoin Brennan, Catherine Godson   +7 more
doaj   +1 more source

Spinal actions of lipoxin A4 and 17(R)-resolvin D1 attenuate inflammation-induced mechanical hypersensitivity and spinal TNF release. [PDF]

PLoS ONE, 2013
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain ...
Sally Abdelmoaty, Gustaf Wigerblad, Duygu B Bas, Simone Codeluppi, Teresa Fernandez-Zafra, El-Sayed El-Awady, Yasser Moustafa, Alaa El-Din S Abdelhamid, Ernst Brodin, Camilla I Svensson   +9 more
doaj   +1 more source