Results 11 to 20 of about 261 (130)
Lipoxin and Aspirin-Triggered Lipoxins [PDF]
The Scientific World Journal, 2010 Lipoxins and their 15 epimers, aspirin triggered lipoxins (ATL), are eicosanoids derived from sequential lipoxygenase (LO) metabolism of arachidonic acid.
Mario Romano
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The Scientific World JOURNAL, 2007 Lipoxins (LXs) represent a class of arachidonic acid (AA) metabolites that carry potent immunoregulatory and anti-inflammatory properties, LXA4and LXB4being the main components of this series. LXs are generated by cooperation between 5-lipoxygenase (LO) and 12- or 15-LO during cell-cell interactions or by single cell types. LX epimers at carbon 15, the
ROMANO, Mario +2 more
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Lipoxins: regulators of resolution [PDF]
Current Opinion in Pharmacology, 2010 Persistent inflammation underlies many prevalent diseases including atherosclerosis and diabetes. There is a growing appreciation that inflammation and its active resolution may be modulated by endogenously produced lipids. Pre-eminent amongst these mediators are lipoxin [LX]A4 and LXB4.
Ryan, Aidan, Godson, Catherine
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Bioengineering, 2023 Despite the formidable treatment challenges of pancreatic ductal adenocarcinoma (PDAC), considerable progress has been made in improving drug delivery via pioneering nanocarriers. These innovations are geared towards overcoming the obstacles presented by
Saborni Chattopadhyay +3 more
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Journal of Lipid Research, 2022 Oxylipins are important biological regulators that have received extensive research attention. Due to the extremely low concentrations, large concentration variations, and high structural similarity of many oxylipins, the quantitative analysis of ...
Xian Fu +6 more
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iScience, 2022 Summary: Adipose tissue inflammation drives obesity-related cardiometabolic diseases. Enhancing endogenous resolution mechanisms through administration of lipoxin A4, a specialized pro-resolving lipid mediator, was shown to reduce adipose inflammation ...
Matúš Soták +19 more
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Targeting Neutrophil Apoptosis for Enhancing the Resolution of Inflammation
Cells, 2013 Resolution of acute inflammation is an active process that requires inhibition of further leukocyte recruitment and removal of leukocytes from inflamed sites. Emigrated neutrophils undergo apoptosis before being removed by scavenger macrophages.
Driss El Kebir, János G. Filep
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Lipoxins as biomarkers of lupus and other inflammatory conditions
Lipids in Health and Disease, 2011 Inflammatory events persist in systemic lupus erythematosus (lupus) despite the use of anti-inflammatory (both steroidal and non-steroidal) and immunosuppressive drugs leading to delay in the healing/repair process and so tissue/organ damage continues ...
Das Undurti N
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Frontiers in Immunology, 2020 Asthma represents one of the leading chronic diseases worldwide and causes a high global burden of death and disability. In asthmatic patients, the exacerbation and chronification of the inflammatory response are often related to a failure in the ...
Daniella Bianchi Reis Insuela +5 more
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Immunomodulation of periodontitis with SPMs
Frontiers in Oral Health, 2023 Inflammation is a critical component in the pathophysiology of numerous disease processes, with most therapeutic modalities focusing on its inhibition in order to achieve treatment outcomes.
Vaibhav Sahni +2 more
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