Results 11 to 20 of about 6,206 (204)
Lipoxins: nature's way to resolve inflammation
Journal of Inflammation Research, 2015 Jayashree A Chandrasekharan, Neelam Sharma-Walia HM Bligh Cancer Research Laboratories, Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USAAbstract: An effective ...
Chandrasekharan JA, Sharma-Walia N
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Resolution-Based Therapies: The Potential of Lipoxins to Treat Human Diseases
Frontiers in Immunology, 2021 Inflammation is an a physiological response instead an essential response of the organism to injury and its adequate resolution is essential to restore homeostasis.
Rafael I. Jaén +9 more
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Acta Biomedica ScientificaAsthma is the most important medical and social problem of our time due to its widespread prevalence, chronic course and heterogeneity, which determines the complexity of treating this disease.
O. Yu. Kytikova +2 more
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Antioxidants, 2022 Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig +6 more
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Integrated pro-resolving mechanisms: a new dimension for optimizing anti-inflammatory therapy in asthma – a review of impaired inflammation resolution in airway remodeling [PDF]
Frontiers in ImmunologyThe core pathology of asthma involves not only inflammation amplification but also a systemic failure of inflammation resolution programs. This review first summarizes the Specialized Pro-resolving Mediators (SPM) family, efferocytosis, and their ...
Bingxue Zhang +10 more
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Advances in the Chemistry and Biology of Specialised Pro-Resolving Mediators (SPMs) [PDF]
MoleculesThis review article assembles key recent advances in the synthetic chemistry and biology of specialised pro-resolving mediators (SPMs). The major medicinal chemistry developments in the design, synthesis and biological evaluation of synthetic SPM ...
Lucy Byrne, Patrick J. Guiry
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Acta Marisiensis - Seria MedicaDiabetes mellitus type 2 is a chronic disease caused by insulin resistance. Whilst first originating in the adipose tissue, this pathophysiological process later affects the muscles and the liver as well.
Bergo Ivan, Pastorello Ylenia
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Lipoxins A4 and B4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation [PDF]
Journal of NeuroinflammationLipoxins are small lipids that are potent endogenous mediators of systemic inflammation resolution in a variety of diseases. We previously reported that Lipoxins A4 and B4 (LXA4 and LXB4) have protective activities against neurodegenerative injury.
Izhar Livne-Bar +3 more
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The Scientific World JOURNAL, 2007 Lipoxins (LXs) represent a class of arachidonic acid (AA) metabolites that carry potent immunoregulatory and anti-inflammatory properties, LXA4and LXB4being the main components of this series. LXs are generated by cooperation between 5-lipoxygenase (LO) and 12- or 15-LO during cell-cell interactions or by single cell types. LX epimers at carbon 15, the
ROMANO, Mario +2 more
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Infection, Inflammation, and Immunity in Sepsis
Biomolecules, 2023 Sepsis is triggered by microbial infection, injury, or even major surgery. Both innate and adaptive immune systems are involved in its pathogenesis. Cytoplasmic presence of DNA or RNA of the invading organisms or damaged nuclear material (in the form of ...
Undurti N. Das
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