Results 31 to 40 of about 3,395 (149)
Endogenous inhibitory mechanisms in asthma
Journal of Allergy and Clinical Immunology: Global, 2023 Endogenous inhibitory mechanisms promote resolution of inflammation, enhance tissue repair and integrity, and promote homeostasis in the lung. These mechanisms include steroid hormones, regulatory T cells, IL-10, prostaglandin E2, prostaglandin I2 ...
Sergio E. Chiarella, MD +1 more
doaj +1 more source
The Role of Immunoresolvents in Atherosclerosis: A Mini-Review on Their Biology and Therapeutic Opportunities. [PDF]
Health Sci RepABSTRACT Background and Aims Atherosclerosis is a lipid‐induced chronic inflammatory cardiovascular disorder denoted by the infiltration of immune cells and the agglomeration of lipids in the intima, the innermost layer, of the arteries of large and medium sizes.
Lotfi R +4 more
europepmc +2 more sources
Frontiers in Psychiatry, 2020 Inflammation has been identified as one of the main pathophysiological mechanisms underlying neuropsychiatric and neurodegenerative disorders. Despite the role of inflammation in those conditions, there is still a lack of effective anti-inflammatory ...
Juliette Giacobbe +4 more
doaj +1 more source
, 2022 Autoimmune diseases are driven by TH17 cells that secrete pro-inflammatory cytokines, especially IL-17. Under normal physiological conditions, autoreactive T cells are suppressed by TGF-β and IL-10 secreted by microglia and dendritic cells.
Das, Undurti N.
core +1 more source
, 2023 Maresins are lipid mediators derived from omega-3 fatty acids with anti-inflammatory and pro-resolving properties, capable of promoting tissue regeneration and potentially serving as a therapeutic agent for chronic inflammatory diseases.
Wei-Ming Chang +4 more
core +1 more source
Lipoxins as biomarkers of lupus and other inflammatory conditions
Lipids in Health and Disease, 2011 Inflammatory events persist in systemic lupus erythematosus (lupus) despite the use of anti-inflammatory (both steroidal and non-steroidal) and immunosuppressive drugs leading to delay in the healing/repair process and so tissue/organ damage continues ...
Das Undurti N
doaj +1 more source
Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis. [PDF]
, 2018 protocolSolid-phase extraction coupled with liquid chromatography tandem mass spectrometry provides a robust and sensitive approach for the identification and quantitation of specialized pro-resolving mediators (lipoxins, resolvins, protectins, and ...
Dalli, J +7 more
core +1 more source
Frontiers in PharmacologySepsis-associated lung injury (SALI) is a critical condition with high mortality. Current therapies are limited, necessitating novel approaches. This review highlights the potential of exogenous Specialized Pro-resolving Mediators (SPMs), including ...
Jiwei Shen +26 more
doaj +1 more source
Resolvins, Specialized Proresolving Lipid Mediators, and Their Potential Roles in Metabolic Diseases [PDF]
, 2014 Inflammation is associated with the development of diseases characterized by altered nutrient metabolism. Although an acute inflammatory response is host-protective and normally self-limited, chronic low-grade inflammation associated with metabolic ...
Clària, Joan +5 more
core +1 more source
Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions
, 2019 The endogenous cellular and molecular mechanisms that control acute inflammation and its resolution are of wide interest. Using self-resolving inflammatory exudates and lipidomics, we have identified a new pathway involving biosynthesis of potent ...
Yang, Rong +7 more
core +1 more source