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Mediators of Inflammation, 2010 Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones. The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm the presence of ...
Monica Ottaviani +2 more
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Lipid Mediators in Inflammation [PDF]
Microbiology Spectrum, 2016 Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core +5 more sources
Lipid droplets and lipid mediators in viral infection and immunity [PDF]
FEMS Microbiology Reviews, 2021 AbstractLipid droplets (LDs) contribute to key pathways important for the physiology and pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids, protein sequestration, removal of toxic lipids and cellular communication; however, recent advancements in the field show these organelles as essential for various cellular
Ebony A Monson +2 more
exaly +4 more sources
The roles of lipid mediators in type I hypersensitivity
Journal of Pharmacological Sciences, 2021 Type I hypersensitivity is an immediate immune reaction that involves IgE-mediated activation of mast cells. Activated mast cells release chemical mediators, such as histamine and lipid mediators, which cause allergic reactions.
Tatsuro Nakamura
doaj +3 more sources
Eosinophil Recruitment and Activation: The Role of Lipid Mediators
Frontiers in Pharmacology, 2013 Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving eosinophil selective accumulation in sites of allergic inflammation are well established and ...
Tatiana eLuna-Gomes +2 more
doaj +3 more sources
Docosahexaenoic Acid Increases the Pro-Resolving Brain Lipid Mediators of Inflammation in Rat Pups Prenatally Exposed to Alcohol [PDF]
LifeFetal alcohol spectrum disorder (FASD/FAS) is a chronic inflammatory process of the fetal brain induced by alcohol and mediated by pro-inflammatory (PILM) and pro-resolving (PRLM) lipid mediators of inflammation.
Enrique M. Ostrea +5 more
doaj +2 more sources
Frontiers in Immunology, 2020 Polyunsaturated fatty acid-derived specialized pro-resolving lipid mediators (SPMs) play an important role in modulating inflammation. The aim of the study was to compare profiles of SPMs, SPM related lipid mediators and SPM receptor gene expression in ...
Brittney Ferguson +11 more
doaj +3 more sources
Roles of lipid mediators in early pregnancy events [PDF]
Reproductive Medicine and BiologyBackground Early pregnancy events, including embryo implantation, are critical for maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling pathways implicated in establishing early pregnancy, a comprehensive understanding ...
Shizu Aikawa, Yasushi Hirota
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Differential effect of an evolving amyloid and tau pathology on brain phospholipids and bioactive lipid mediators in rat models of Alzheimer-like pathology [PDF]
Journal of NeuroinflammationBackground Brain inflammation contributes significantly to the pathophysiology of Alzheimer’s disease, and it is manifested by glial cell activation, increased production of cytokines/chemokines, and a shift in lipid mediators from a pro-homeostatic to a
Sonia Do Carmo +9 more
doaj +2 more sources
Frontiers in Immunology, 2021 Failure of resolution pathways in periodontitis is reflected in levels of specialized pro-resolving lipid mediators (SPMs) and SPM pathway markers but their relationship with the subgingival microbiome is unclear.
Chun-Teh Lee +9 more
doaj +1 more source