Results 1 to 10 of about 203,017 (297)
Lipid droplets and lipid mediators in viral infection and immunity [PDF]
FEMS Microbiology Reviews, 2021 AbstractLipid droplets (LDs) contribute to key pathways important for the physiology and pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids, protein sequestration, removal of toxic lipids and cellular communication; however, recent advancements in the field show these organelles as essential for various cellular
Ebony A Monson +2 more
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Eosinophil Recruitment and Activation: The Role of Lipid Mediators
Frontiers in Pharmacology, 2013 Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving eosinophil selective accumulation in sites of allergic inflammation are well established and ...
Tatiana eLuna-Gomes +2 more
doaj +4 more sources
Linoleate-Rich Safflower Oil Diet Increases Linoleate-Derived Bioactive Lipid Mediators in Plasma, and Brown and White Adipose Depots of Healthy Mice [PDF]
Metabolites, 2022 Polyunsaturated fats are energy substrates and precursors to the biosynthesis of lipid mediators of cellular processes. Adipose tissue not only provides energy storage, but influences whole-body energy metabolism through endocrine functions.
Deena B. Snoke +5 more
doaj +2 more sources
Mediators of Inflammation, 2010 Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones. The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm the presence of ...
Monica Ottaviani +2 more
doaj +4 more sources
The roles of lipid mediators in type I hypersensitivity
Journal of Pharmacological Sciences, 2021 Type I hypersensitivity is an immediate immune reaction that involves IgE-mediated activation of mast cells. Activated mast cells release chemical mediators, such as histamine and lipid mediators, which cause allergic reactions.
Tatsuro Nakamura
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Associations between Plasma Lipid Mediators and Chronic Daily Headache Outcomes in Patients Randomized to a Low Linoleic Acid Diet with or without Added Omega-3 Fatty Acids [PDF]
Metabolites, 2023 A previous report showed that 12-week lowering of dietary omega-6 linoleic acid (LA) coupled with increased omega-3 polyunsaturated fatty acid (PUFA) intake (H3-L6 diet) reduced headache frequency and improved quality of life in patients with chronic ...
Qing Shen +9 more
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Host Lipid Mediators in Leprosy: The Hypothesized Contributions to Pathogenesis
Frontiers in Immunology, 2018 The spectrum of clinical forms observed in leprosy and its pathogenesis are dictated by the host’s immune response against Mycobacterium leprae, the etiological agent of leprosy.
Carlos A. M. Silva, John T. Belisle
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Docosahexaenoic Acid Increases the Pro-Resolving Brain Lipid Mediators of Inflammation in Rat Pups Prenatally Exposed to Alcohol [PDF]
LifeFetal alcohol spectrum disorder (FASD/FAS) is a chronic inflammatory process of the fetal brain induced by alcohol and mediated by pro-inflammatory (PILM) and pro-resolving (PRLM) lipid mediators of inflammation.
Enrique M. Ostrea +5 more
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Frontiers in Immunology, 2020 Polyunsaturated fatty acid-derived specialized pro-resolving lipid mediators (SPMs) play an important role in modulating inflammation. The aim of the study was to compare profiles of SPMs, SPM related lipid mediators and SPM receptor gene expression in ...
Brittney Ferguson +11 more
doaj +3 more sources
A mitochondrial pathway for biosynthesis of lipid mediators [PDF]
Nature Chemistry, 2014 The central role of mitochondria in metabolic pathways and in cell-death mechanisms requires sophisticated signalling systems. Essential in this signalling process is an array of lipid mediators derived from polyunsaturated fatty acids. However, the molecular machinery for the production of oxygenated polyunsaturated fatty acids is localized in the ...
Tyurina, Yulia Y. +18 more
openaire +3 more sources