Results 1 to 10 of about 205,374 (259)

The roles of lipid mediators in type I hypersensitivity

Journal of Pharmacological Sciences, 2021
Type I hypersensitivity is an immediate immune reaction that involves IgE-mediated activation of mast cells. Activated mast cells release chemical mediators, such as histamine and lipid mediators, which cause allergic reactions.
Tatsuro Nakamura
exaly   +3 more sources

Eosinophil recruitment and activation: the role of lipid mediators

Frontiers in Pharmacology, 2013
Eosinophils are effector cells that migrate toward several mediators released at inflammatory sites to perform their multiple functions. The mechanisms driving eosinophil selective accumulation in sites of allergic inflammation are well established and ...
Patricia Bozza, Christianne Bandeira-Melo, Tatiana Luna-Gomes   +2 more
exaly   +3 more sources

Docosahexaenoic Acid Increases the Pro-Resolving Brain Lipid Mediators of Inflammation in Rat Pups Prenatally Exposed to Alcohol [PDF]

Life
Fetal alcohol spectrum disorder (FASD/FAS) is a chronic inflammatory process of the fetal brain induced by alcohol and mediated by pro-inflammatory (PILM) and pro-resolving (PRLM) lipid mediators of inflammation.
Enrique M. Ostrea, Deepak Yadav, Charlie T. Cheng, Esther D. Kisseih, Krishna R. Maddipati, Ronald L. Thomas   +5 more
doaj   +2 more sources

Fatty Acids, Lipid Mediators, and T-Cell Function

Frontiers in Immunology, 2014
Research towards the mechanisms underlying obesity-linked complications has intensified during the last years. As a consequence, it has become clear that metabolism and immunity are intimately linked.
Anja de Jong, Andréea Ioan, Margreet Kloppenburg   +2 more
exaly   +3 more sources

Roles of lipid mediators in early pregnancy events [PDF]

Reproductive Medicine and Biology
Background Early pregnancy events, including embryo implantation, are critical for maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling pathways implicated in establishing early pregnancy, a comprehensive understanding ...
Shizu Aikawa, Yasushi Hirota
doaj   +2 more sources

Subgingival Microbiome and Specialized Pro-Resolving Lipid Mediator Pathway Profiles Are Correlated in Periodontal Inflammation

Frontiers in Immunology, 2021
Failure of resolution pathways in periodontitis is reflected in levels of specialized pro-resolving lipid mediators (SPMs) and SPM pathway markers but their relationship with the subgingival microbiome is unclear.
Chun-Teh Lee, Ruoxing Li, Lisha Zhu, Gena D. Tribble, W. Jim Zheng, Brittney Ferguson, Krishna Rao Maddipati, Nikola Angelov, Thomas E. Van Dyke, Thomas E. Van Dyke   +9 more
doaj   +1 more source

Linoleate-Rich Safflower Oil Diet Increases Linoleate-Derived Bioactive Lipid Mediators in Plasma, and Brown and White Adipose Depots of Healthy Mice

Metabolites, 2022
Polyunsaturated fats are energy substrates and precursors to the biosynthesis of lipid mediators of cellular processes. Adipose tissue not only provides energy storage, but influences whole-body energy metabolism through endocrine functions.
Deena B. Snoke, Austin Angelotti, Kamil Borkowski, Rachel M. Cole, John W. Newman, Martha A. Belury   +5 more
doaj   +1 more source

Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin interventionResearch in context

EBioMedicine, 2023
Summary: Background: Persons with HIV (PWH) have an increased risk of cardiovascular disease (CVD) compared to HIV-seronegative individuals (SN). Inflammation contributes to this risk but the role of lipid mediators, with central roles in inflammation ...
Jesmond Dalli, Douglas Kitch, Meagan P. O'Brien, Peter W. Hunt, Nicholas Funderburg, Daniela Moisi, Amita Gupta, Todd T. Brown, Phyllis C. Tien, Judith A. Aberg, Rupak Shivakoti   +10 more
doaj   +1 more source

Current knowledge of the implication of lipid mediators in psoriasis

Frontiers in Immunology, 2022
The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions of the skin is its barrier function, mediated notably by the lipids of the stratum corneum, and
Mélissa Simard, Mélissa Simard, Sophie Morin, Sophie Morin, Zainab Ridha, Roxane Pouliot, Roxane Pouliot   +6 more
doaj   +1 more source

LimeMap: a comprehensive map of lipid mediator metabolic pathways

npj Systems Biology and Applications, 2021
Lipid mediators are major factors in multiple biological functions and are strongly associated with disease. Recent lipidomics approaches have made it possible to analyze multiple metabolites and the associations of individual lipid mediators.
Akinori Nishi, Katsuya Ohbuchi, Noriko Kaifuchi, Chika Shimobori, Hirotaka Kushida, Masahiro Yamamoto, Yoshihiro Kita, Suzumi M. Tokuoka, Ayako Yachie, Yukiko Matsuoka, Hiroaki Kitano   +10 more
doaj   +1 more source