Results 11 to 20 of about 203,017 (297)
Roles of lipid mediators in early pregnancy events [PDF]
Reproductive Medicine and BiologyBackground Early pregnancy events, including embryo implantation, are critical for maintaining a healthy pregnancy and facilitating childbirth. Despite numerous signaling pathways implicated in establishing early pregnancy, a comprehensive understanding ...
Shizu Aikawa, Yasushi Hirota
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Genetic analyses of circulating PUFA-derived mediators identifies heritable dihydroxyeicosatrienoic acid species [PDF]
, 2022 Estimates of heritability are the first step in identifying a trait with substantial variation due to genetic factors. Large-scale genetic analyses can identify the DNA variants that influence the levels of circulating lipid species and the statistical ...
Kendall, Alexandra C +4 more
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Frontiers in Immunology, 2021 Failure of resolution pathways in periodontitis is reflected in levels of specialized pro-resolving lipid mediators (SPMs) and SPM pathway markers but their relationship with the subgingival microbiome is unclear.
Chun-Teh Lee +9 more
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EBioMedicine, 2023 Summary: Background: Persons with HIV (PWH) have an increased risk of cardiovascular disease (CVD) compared to HIV-seronegative individuals (SN). Inflammation contributes to this risk but the role of lipid mediators, with central roles in inflammation ...
Jesmond Dalli +10 more
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Lipid-Mediated Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Receptor-mediated endocytosis is used by a number of viruses and toxins to gain entry into cells. Some have evolved to use specific lipids in the plasma membrane as their receptors. They include bacterial toxins such as Shiga and Cholera toxin and viruses such as mouse polyoma virus and simian virus 40. Through multivalent binding to glycosphingolipids,
Ewers, Helge, Helenius, Ari
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Lipid Mediators in Inflammation [PDF]
Microbiology Spectrum, 2016 ABSTRACTLipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), each lipid displays ...
Bennett, M, Gilroy, DW
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Current knowledge of the implication of lipid mediators in psoriasis
Frontiers in Immunology, 2022 The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions of the skin is its barrier function, mediated notably by the lipids of the stratum corneum, and
Mélissa Simard +6 more
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LimeMap: a comprehensive map of lipid mediator metabolic pathways
npj Systems Biology and Applications, 2021 Lipid mediators are major factors in multiple biological functions and are strongly associated with disease. Recent lipidomics approaches have made it possible to analyze multiple metabolites and the associations of individual lipid mediators.
Akinori Nishi +10 more
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Lipid Mediators in Inflammatory Disorders [PDF]
Drugs, 1998 During the past few decades, intensive collaborative research in the fields of chronic and acute inflammatory disorders has resulted in a better understanding of the pathophysiology and diagnosis of these diseases. Modern therapeutic approaches are still not satisfactory and shock, sepsis and multiple organ failure remain the great challenge in ...
Heller, Axel R. +3 more
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Molecular Metabolism, 2022 Objective: Physical activity has been shown to reduce the risk of CVD mortality in large-cohort longitudinal studies; however, the mechanisms underpinning the beneficial effects of exercise remain incompletely understood.
Ernesto Pena Calderin +7 more
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