Results 11 to 20 of about 328,980 (298)
Metabolites, 2022 Polyunsaturated fats are energy substrates and precursors to the biosynthesis of lipid mediators of cellular processes. Adipose tissue not only provides energy storage, but influences whole-body energy metabolism through endocrine functions.
Deena B. Snoke +5 more
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EBioMedicine, 2023 Summary: Background: Persons with HIV (PWH) have an increased risk of cardiovascular disease (CVD) compared to HIV-seronegative individuals (SN). Inflammation contributes to this risk but the role of lipid mediators, with central roles in inflammation ...
Jesmond Dalli +10 more
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Lipid-Mediated Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Receptor-mediated endocytosis is used by a number of viruses and toxins to gain entry into cells. Some have evolved to use specific lipids in the plasma membrane as their receptors. They include bacterial toxins such as Shiga and Cholera toxin and viruses such as mouse polyoma virus and simian virus 40. Through multivalent binding to glycosphingolipids,
Ewers, Helge, Helenius, Ari
openaire +4 more sources
Current knowledge of the implication of lipid mediators in psoriasis
Frontiers in Immunology, 2022 The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions of the skin is its barrier function, mediated notably by the lipids of the stratum corneum, and
Mélissa Simard +6 more
doaj +1 more source
Relationship between Sustained Reductions in Plasma Lipid and Lipoprotein Concentrations with Apheresis and Plasma Levels and mRNA Expression of PTX3 and Plasma Levels of hsCRP in Patients with HyperLp(a)lipoproteinemia [PDF]
, 2016 The effect of lipoprotein apheresis (Direct Adsorption of Lipids, DALI) (LA) on plasma levels of pentraxin 3 (PTX3), an inflammatory marker that reflects coronary plaque vulnerability, and expression of PTX3 mRNA was evaluated in patients with hyperLp(a ...
De Nève, Joel +6 more
core +10 more sources
LimeMap: a comprehensive map of lipid mediator metabolic pathways
npj Systems Biology and Applications, 2021 Lipid mediators are major factors in multiple biological functions and are strongly associated with disease. Recent lipidomics approaches have made it possible to analyze multiple metabolites and the associations of individual lipid mediators.
Akinori Nishi +10 more
doaj +1 more source
Lipid Mediators in Inflammatory Disorders [PDF]
Drugs, 1998 During the past few decades, intensive collaborative research in the fields of chronic and acute inflammatory disorders has resulted in a better understanding of the pathophysiology and diagnosis of these diseases. Modern therapeutic approaches are still not satisfactory and shock, sepsis and multiple organ failure remain the great challenge in ...
Heller, Axel R. +3 more
openaire +3 more sources
Molecular Metabolism, 2022 Objective: Physical activity has been shown to reduce the risk of CVD mortality in large-cohort longitudinal studies; however, the mechanisms underpinning the beneficial effects of exercise remain incompletely understood.
Ernesto Pena Calderin +7 more
doaj +1 more source
Hepatic lipase:structure/function relationship, synthesis,and regulation
Journal of Lipid Research, 2002 Hepatic lipase (HL) is a lipolytic enzyme, synthesized by hepatocytes and found localized at the surface of liver sinusoid capillaries. In humans, the enzyme is mostly bound onto heparan-sulfate proteoglycans at the surface of hepatocytes and also of ...
Bertrand Perret +5 more
doaj +1 more source
Obesity-induced changes in lipid mediators persist after weight loss. [PDF]
, 2017 BackgroundObesity induces significant changes in lipid mediators, however, the extent to which these changes persist after weight loss has not been investigated.Subjects/methodsWe fed C57BL6 mice a high-fat diet to generate obesity and then switched the ...
Börgeson, E +9 more
core +2 more sources