Results 41 to 50 of about 203,017 (297)
Communicating with the dead: lipids, lipid mediators and extracellular vesicles [PDF]
Biochemical Society Transactions, 2018 Apoptosis is a key event in the control of inflammation. However, for this to be successful, dying cells must efficiently and effectively communicate their presence to phagocytes to ensure timely removal of dying cells. Here, we consider apoptotic cell-derived extracellular vesicles and the role of contained lipids and lipid mediators in ensuring ...
Devitt, Andrew +2 more
openaire +2 more sources
Particle and Fibre Toxicology, 2012 Background Exposure to ultrafine particles exerts diverse harmful effects including aggravation of pulmonary diseases like asthma. Recently we demonstrated in a mouse model for allergic airway inflammation that particle-derived oxidative stress plays a ...
Beck-Speier Ingrid +4 more
doaj +1 more source
Biomolecules, 2023 Psoriasis is a skin disease characterized by epidermal hyperplasia and an inappropriate activation of the adaptive immunity. A dysregulation of the skin’s lipid mediators is reported in the disease with a predominance of the inflammatory cascade derived ...
Sophie Morin +5 more
doaj +1 more source
Occurrence and biological activity of palmitoleic acid isomers in phagocytic cells
Journal of Lipid Research, 2018 Recent studies have highlighted the role of palmitoleic acid [16:1n-7 (cis-9-hexadecenoic acid)] as a lipid hormone that coordinates cross-talk between liver and adipose tissue and exerts anti-inflammatory protective effects on hepatic steatosis and ...
Alma M. Astudillo +6 more
doaj +1 more source
Journal of Applied Animal Research, 2021 Although polyunsaturated fatty acids (PUFAs) have gained attention because of their physiological effects on inflammation and stress, their derivatives, termed lipid mediators, have been rarely examined, especially in laying hens. In this study, we aimed
Sang-Mok Lee +8 more
doaj +1 more source
TGFv/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation
, 2022 S.60-675-Lipoxygenase (5-LO) catalyzes the initial two steps of the conversion of arachidonic acid to leukotrienes which represent a group of pro-inflammatory lipid mediators involved in immune defense reactions as well as inflammation, allergy and ...
Marschalek, R. +6 more
core +1 more source
Mast cells: from lipid droplets to lipid mediators [PDF]
Clinical Science, 2013 LDs (lipid droplets) are metabolically highly active intracellular organelles. The lipid and protein profiles of LDs are cell-type-specific, and they undergo dynamic variation upon changes in the physiological state of a cell. It is well known that the main function of the LDs in adipocytes is to ensure energy supply and to maintain lipid homoeostasis ...
Dichlberger, Andrea +2 more
openaire +2 more sources
Maresins: Specialized Proresolving Lipid Mediators and Their Potential Role in Inflammatory-Related Diseases [PDF]
, 2018 Acute inflammatory responses are host-protective and normally self-limited; these responses can maintain cell homeostasis and promote defense against various infections and damage factors.
Ming Wan +9 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
, 2019 Individuals with concurrent tuberculosis (TB) and Type 2 diabetes (DM) have a higher risk of adverse outcomes. To better understand potential immunological differences, we utilized a comprehensive panel to characterize pro-inflammatory and pro-resolving (
Lokhande, R +27 more
core +1 more source