Results 21 to 30 of about 194,410 (258)
Lipid-Mediated Endocytosis [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Receptor-mediated endocytosis is used by a number of viruses and toxins to gain entry into cells. Some have evolved to use specific lipids in the plasma membrane as their receptors. They include bacterial toxins such as Shiga and Cholera toxin and viruses such as mouse polyoma virus and simian virus 40. Through multivalent binding to glycosphingolipids,
Ewers, Helge, Helenius, Ari
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Lipid Mediators in Inflammation [PDF]
Microbiology Spectrum, 2016 ABSTRACTLipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), each lipid displays ...
Bennett, M, Gilroy, DW
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Current knowledge of the implication of lipid mediators in psoriasis
Frontiers in Immunology, 2022 The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions of the skin is its barrier function, mediated notably by the lipids of the stratum corneum, and
Mélissa Simard +6 more
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LimeMap: a comprehensive map of lipid mediator metabolic pathways
npj Systems Biology and Applications, 2021 Lipid mediators are major factors in multiple biological functions and are strongly associated with disease. Recent lipidomics approaches have made it possible to analyze multiple metabolites and the associations of individual lipid mediators.
Akinori Nishi +10 more
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Lipid Mediators in Inflammatory Disorders [PDF]
Drugs, 1998 During the past few decades, intensive collaborative research in the fields of chronic and acute inflammatory disorders has resulted in a better understanding of the pathophysiology and diagnosis of these diseases. Modern therapeutic approaches are still not satisfactory and shock, sepsis and multiple organ failure remain the great challenge in ...
Heller, Axel R. +3 more
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Molecular Metabolism, 2022 Objective: Physical activity has been shown to reduce the risk of CVD mortality in large-cohort longitudinal studies; however, the mechanisms underpinning the beneficial effects of exercise remain incompletely understood.
Ernesto Pena Calderin +7 more
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Hepatic lipase:structure/function relationship, synthesis,and regulation
Journal of Lipid Research, 2002 Hepatic lipase (HL) is a lipolytic enzyme, synthesized by hepatocytes and found localized at the surface of liver sinusoid capillaries. In humans, the enzyme is mostly bound onto heparan-sulfate proteoglycans at the surface of hepatocytes and also of ...
Bertrand Perret +5 more
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16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens
Metabolites, 2020 Respiratory tract infections are a global health problem. The main causative agents of these infections are influenza A virus (IAV), Staphylococcus aureus (S. aureus), and Streptococcus pneumoniae (S. pneumoniae).
Daniel Schultz +8 more
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Tailored Polymer-Based Selective Extraction of Lipid Mediators from Biological Samples
Metabolites, 2021 Lipid mediators, small molecules involved in regulating inflammation and its resolution, are a class of lipids of wide interest as their levels in blood and tissues may be used to monitor health and disease states or the effect of new treatments.
Yohannes Abere Ambaw +10 more
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Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Nrf2 Activators
Antioxidants, 2020 Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered class of biologically active lipids with anti-inflammatory and anti-diabetic properties.
Siddabasave Gowda B. Gowda +4 more
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