Results 21 to 30 of about 328,980 (298)

16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens

Metabolites, 2020
Respiratory tract infections are a global health problem. The main causative agents of these infections are influenza A virus (IAV), Staphylococcus aureus (S. aureus), and Streptococcus pneumoniae (S. pneumoniae).
Daniel Schultz, Surabhi Surabhi, Nicolas Stelling, Michael Rothe, KoInfekt Study Group, Karen Methling, Sven Hammerschmidt, Nikolai Siemens, Michael Lalk   +8 more
doaj   +1 more source

Tailored Polymer-Based Selective Extraction of Lipid Mediators from Biological Samples

Metabolites, 2021
Lipid mediators, small molecules involved in regulating inflammation and its resolution, are a class of lipids of wide interest as their levels in blood and tissues may be used to monitor health and disease states or the effect of new treatments.
Yohannes Abere Ambaw, Sandra Rinne Dahl, Yan Chen, Tyge Greibrokk, Elsa Lundanes, Issam Lazraq, Sudhirkumar Shinde, Jayashree Selvalatchmanan, Markus R. Wenk, Börje Sellergren, Federico Torta   +10 more
doaj   +1 more source

Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization,secondary mediators, and Rac [PDF]

, 2010
The C-type lectin-like receptor 2 (CLEC-2)activates platelets through Src and Syk tyrosine kinases via a single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM).Here, we demonstrate using sucrose gradient ...
Alice Y. Pollitt, Atkinson, Barrow, Beata Grygielska, Bertrand Leblond, Bodin, Bodin, Boggon, Christou, Colonna, Eble, Ezumi, Fuller, He, Hooley, Hughes, Huysamen, Johannes A. Eble, Kerrigan, Laurent Désiré, Lee, Locke, May, McCarty, Pestina, Piechulek, Pierce, Pleines, Quek, Sancho, Schacht, Shutes, Simons, Sobanov, Spalton, Steve P. Watson, Suzuki-Inoue, Suzuki-Inoue, Tolias, Walliser, Watson, Watson, Wonerow, Wonerow, Xu   +44 more
core   +1 more source

Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Nrf2 Activators

Antioxidants, 2020
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered class of biologically active lipids with anti-inflammatory and anti-diabetic properties.
Siddabasave Gowda B. Gowda, Hirotoshi Fuda, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui   +4 more
doaj   +1 more source

The Involvement of Lipid Mediators in the Mechanisms of Exercise-Induced Muscle Damage

Physiologia, 2023
Lipid mediators are a class of signaling molecules that play important roles in various physiological processes, including inflammation, blood pressure regulation, and energy metabolism.
Athanasios G. Gakis, Tzortzis Nomikos, Anastassios Philippou, Smaragdi Antonopoulou   +3 more
doaj   +1 more source

Albumin Lipidomics Reveals Meaningful Compositional Changes in Advanced Cirrhosis and Its Potential to Promote Inflammation Resolution

Hepatology Communications, 2022
Albumin infusions are therapeutically used to revert hypoalbuminemia and to replace the extensively oxidized albumin molecule circulating in patients with acutely decompensated (AD) cirrhosis.
Mireia Casulleras, Roger Flores‐Costa, Marta Duran‐Güell, Ingrid W. Zhang, Cristina López‐Vicario, Anna Curto, Javier Fernández, Vicente Arroyo, Joan Clària   +8 more
doaj   +1 more source

Lipids in Liver Failure Syndromes: A Focus on Eicosanoids, Specialized Pro-Resolving Lipid Mediators and Lysophospholipids

Frontiers in Immunology, 2022
Lipids are organic compounds insoluble in water with a variety of metabolic and non-metabolic functions. They not only represent an efficient energy substrate but can also act as key inflammatory and anti-inflammatory molecules as part of a network of ...
Florent Artru, Mark J. W. McPhail, Evangelos Triantafyllou, Francesca Maria Trovato   +3 more
doaj   +1 more source

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz, Alio, Ambrosio, Djalilian, Dogru, Li, Nebbioso, Nebbioso, Patel, Rajan, Solomon, Suzuki, Toda, Wilson, Zhu   +14 more
core   +1 more source

Fracture healing and lipid mediators [PDF]

BoneKEy Reports, 2014
Lipid mediators regulate bone regeneration during fracture healing. Prostaglandins and leukotrienes are well-known lipid mediators that regulate inflammation and are synthesized from the Ω-6 fatty acid, arachidonic acid. Cyclooxygenase (COX-1 or COX-2) and 5-lipoxygenase (5-LO) catalyze the initial enzymatic steps in the synthesis of prostaglandins and
J Patrick, O'Connor, Michaele B, Manigrasso, Brian D, Kim, Sangeeta, Subramanian   +3 more
openaire   +2 more sources

Ccl2 and Ccl3 Mediate Neutrophil Recruitment via Induction of Protein Synthesis and Generation of Lipid Mediators [PDF]

, 2009
Objective: Although the chemokines monocyte chemoattractant protein-1 (Ccl2/JE/MCP-1) and macrophage inflammatory protein-1α (Ccl3/MIP-1α) have recently been implicated in neutrophil migration, the underlying mechanisms remain largely unclear.
Berberich, Nina, Bihari, Peter, Khandoga, Alexander G., Krombach, Fritz, Lerchenberger, Max, Rehberg, Markus, Reichel, Christoph A., Zahler, Stefan   +7 more
core   +1 more source