Results 21 to 30 of about 203,017 (297)

CD200 selectively upregulates prostaglandin E2 and D2 synthesis in LPS-treated bone marrow-derived macrophages

, 2022
S.53-59The CD200/CD200R signalling pathway downregulates the synthesis of proinflammatory mediators and induces the synthesis of antiinflammatory mediators in macrophages and microglia.
Angioni, C., Kern, K., Pierre, S., Scholich, K., Schreiber, Y., Ferreirós, N., Thomas, D., Geisslinger, G.   +7 more
core   +1 more source

Hepatic lipase:structure/function relationship, synthesis,and regulation

Journal of Lipid Research, 2002
Hepatic lipase (HL) is a lipolytic enzyme, synthesized by hepatocytes and found localized at the surface of liver sinusoid capillaries. In humans, the enzyme is mostly bound onto heparan-sulfate proteoglycans at the surface of hepatocytes and also of ...
Bertrand Perret, Laurence Mabile, Laurent Martinez, François Tercé, Ronald Barbaras, Xavier Collet   +5 more
doaj   +1 more source

16HBE Cell Lipid Mediator Responses to Mono and Co-Infections with Respiratory Pathogens

Metabolites, 2020
Respiratory tract infections are a global health problem. The main causative agents of these infections are influenza A virus (IAV), Staphylococcus aureus (S. aureus), and Streptococcus pneumoniae (S. pneumoniae).
Daniel Schultz, Surabhi Surabhi, Nicolas Stelling, Michael Rothe, KoInfekt Study Group, Karen Methling, Sven Hammerschmidt, Nikolai Siemens, Michael Lalk   +8 more
doaj   +1 more source

Tailored Polymer-Based Selective Extraction of Lipid Mediators from Biological Samples

Metabolites, 2021
Lipid mediators, small molecules involved in regulating inflammation and its resolution, are a class of lipids of wide interest as their levels in blood and tissues may be used to monitor health and disease states or the effect of new treatments.
Yohannes Abere Ambaw, Sandra Rinne Dahl, Yan Chen, Tyge Greibrokk, Elsa Lundanes, Issam Lazraq, Sudhirkumar Shinde, Jayashree Selvalatchmanan, Markus R. Wenk, Börje Sellergren, Federico Torta   +10 more
doaj   +1 more source

Discovery of Eicosapentaenoic Acid Esters of Hydroxy Fatty Acids as Potent Nrf2 Activators

Antioxidants, 2020
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered class of biologically active lipids with anti-inflammatory and anti-diabetic properties.
Siddabasave Gowda B. Gowda, Hirotoshi Fuda, Takayuki Tsukui, Hitoshi Chiba, Shu-Ping Hui   +4 more
doaj   +1 more source

The Involvement of Lipid Mediators in the Mechanisms of Exercise-Induced Muscle Damage

Physiologia, 2023
Lipid mediators are a class of signaling molecules that play important roles in various physiological processes, including inflammation, blood pressure regulation, and energy metabolism.
Athanasios G. Gakis, Tzortzis Nomikos, Anastassios Philippou, Smaragdi Antonopoulou   +3 more
doaj   +1 more source

Formation of lipoxins and resolvins in human leukocytes

, 2023
Specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins are formed by the consecutive action of 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic acid 12- or 15-lipoxygenases using arachidonic acid, eicosapentaenoic ...
Dieter Steinhilber, Nils Helge Schebb, Schebb, Nils Helge, Kahnt, Astrid S., Astrid S. Kahnt, Steinhilber, Dieter   +5 more
core   +1 more source

Albumin Lipidomics Reveals Meaningful Compositional Changes in Advanced Cirrhosis and Its Potential to Promote Inflammation Resolution

Hepatology Communications, 2022
Albumin infusions are therapeutically used to revert hypoalbuminemia and to replace the extensively oxidized albumin molecule circulating in patients with acutely decompensated (AD) cirrhosis.
Mireia Casulleras, Roger Flores‐Costa, Marta Duran‐Güell, Ingrid W. Zhang, Cristina López‐Vicario, Anna Curto, Javier Fernández, Vicente Arroyo, Joan Clària   +8 more
doaj   +1 more source

Lipids in Liver Failure Syndromes: A Focus on Eicosanoids, Specialized Pro-Resolving Lipid Mediators and Lysophospholipids

Frontiers in Immunology, 2022
Lipids are organic compounds insoluble in water with a variety of metabolic and non-metabolic functions. They not only represent an efficient energy substrate but can also act as key inflammatory and anti-inflammatory molecules as part of a network of ...
Florent Artru, Mark J. W. McPhail, Evangelos Triantafyllou, Francesca Maria Trovato   +3 more
doaj   +1 more source

Editorial-Special issue of the 6th European Workshop on Lipid Mediators

, 2021
S.1 ...
Uydes-Dogan, Birsel Sönmez, Norel, X., Claria, Joan, Topal, Gökce, Norel, Xavier, Bannenberg, G., Topal, G., Schebb, Nils Helge, Bannenberg, Gerard, Clària, J., Schebb, N.H., Steinhilber, D., Uydes-Dogan, B.S., Steinhilber, Dieter   +13 more
core   +1 more source