Results 31 to 40 of about 203,017 (297)
Fracture healing and lipid mediators [PDF]
BoneKEy Reports, 2014 Lipid mediators regulate bone regeneration during fracture healing. Prostaglandins and leukotrienes are well-known lipid mediators that regulate inflammation and are synthesized from the Ω-6 fatty acid, arachidonic acid. Cyclooxygenase (COX-1 or COX-2) and 5-lipoxygenase (5-LO) catalyze the initial enzymatic steps in the synthesis of prostaglandins and
J Patrick, O'Connor +3 more
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, 2022 S.24-325-lipoxygenase (5-LO) is the key enzyme in the biosynthesis of leukotrienes and specialized proresolving lipid mediators (SPM). It is mainly expressed in leukocytes and is part of the innate immune system.
Häfner, A.-K. +2 more
core +1 more source
Lipid mediators and allergic diseases [PDF]
Annals of Allergy, Asthma & Immunology, 2013 To review the basic science and translational relevance of lipid mediators in the pathobiology of allergic diseases.PubMed was searched for articles using the key terms lipid mediator, prostaglandin, prostanoid, leukotriene, thromboxane, asthma, and allergic inflammation.Articles were selected based on their relevance to the goals of this review ...
Laura B, Fanning, Joshua A, Boyce
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Nitro-fatty acids: novel anti-inflammatory lipid mediators
Brazilian Journal of Medical and Biological Research, 2013 Nitro-fatty acids are formed and detected in human plasma, cell membranes, and tissue, modulating metabolic as well as inflammatory signaling pathways.
H. Rubbo
doaj +1 more source
Lipid Mediators in the Resolution of Inflammation [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 Mounting of the acute inflammatory response is crucial for host defense and pivotal to the development of chronic inflammation, fibrosis, or abscess formation versus the protective response and the need of the host tissues to return to homeostasis. Within self-limited acute inflammatory exudates, novel families of lipid mediators are identified, named ...
Charles N, Serhan +3 more
openaire +2 more sources
Cross-talk between bioactive lipid mediators and the unfolded protein response in ischemic stroke
, 2023 Ischemic cerebral stroke is a severe medical condition that affects about 15 million people every year and is the second leading cause of death and disability globally. Ischemic stroke results in neuronal cell death and neurological impairment.
Helike Lõhelaid +11 more
core +1 more source
Journal of Inflammation Research, 2022 Christian Kretzer,1 Paul M Jordan,1 Rossella Bilancia,2 Antonietta Rossi,2 Tuğçe Gür Maz,3 Erden Banoglu,3 Ulrich S Schubert,4,5 Oliver Werz1,5 1Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University
Kretzer C +7 more
doaj
Lipid mediators in diabetic nephropathy [PDF]
Fibrogenesis & Tissue Repair, 2014 The implications of lipid lowering drugs in the treatment of diabetic nephropathy have been considered. At the same time, the clinical efficacy of lipid lowering drugs has resulted in improvement in the cardiovascular functions of chronic kidney disease (CKD) patients with or without diabetes, but no remarkable improvement has been observed in the ...
Srivastava, Swayam +3 more
openaire +2 more sources
Plasma and bronchoalveolar lavage fluid oxylipin levels in experimental porcine lung injury
, 2022 Inflammatory signaling pathways involving eicosanoids and other regulatory lipid mediators are a subject of intensive study, and a role for these in acute lung injury is not yet well understood.
Larsson, Niklas +15 more
core +1 more source
Ratio of pro-resolving and pro-inflammatory lipid mediator precursors as potential markers for aggressive periodontitis. [PDF]
PLoS ONE, 2013 Aggressive periodontitis (AgP) is a rapidly progressing type of periodontal disease in otherwise healthy individuals which causes destruction of the supporting tissues of the teeth.
Hager R Zein Elabdeen +5 more
doaj +1 more source