Results 31 to 40 of about 8,166 (214)
Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia [PDF]
The American Journal of Pathology, 2016 Acute lung injury is a life-threatening condition caused by disruption of the alveolar-capillary barrier leading to edema, influx of inflammatory leukocytes, and impaired gas exchange. Specialized proresolving mediators biosynthesized from essential fatty acids, such as docosahexaenoic acid, have tissue protective effects in acute inflammation. Herein,
Jennifer K, Colby +13 more
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A modular, enantioselective synthesis of resolvins D3, E1, and hybrids [PDF]
, 2020 Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama-Denmark coupling of five- and six-membered cyclic alkenylsiloxanes ...
Streatfeild, Penelope E +4 more
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Can endogenous lipid molecules serve as predictors and prognostic markers of coronary heart disease?
Lipids in Health and Disease, 2008 Dyslipidemia, and inflammatory markers: high-sensitivity C-reactive protein (hs-CRP), myeloperoxidase (MPO), lipoprotein associated phospholipase A2(Lp-PLA2), and lipid peroxides (LP) are insufficient to predict the onset, extent, and prognosis of CHD ...
Das Undurti N
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Frontiers in Pharmacology, 2021 Sevoflurane (SEV), a commonly used volatile anesthetic, has been shown to cause cognitive decline in diabetic rats by aggregating neuroinflammation in the hippocampus, but the underlying mechanisms are unknown.
Qingmei Sun +6 more
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Современная ревматология, 2016 Inflammation is the most important element in the pathogenesis of major human diseases. It determines the fundamental value of anti-inflammatory therapy in the modern concept of targeted pathogenetic treatment.
A. E. Karateev, T. L. Aleinikova
doaj +1 more source
Molecules, 2022 Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente +4 more
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Resolvins on the way to resolution [PDF]
Journal of Experimental Medicine, 2015 ![Figure][1] Insight from Peter Ward Over the past several decades, lipid products have been found to exert both proinflammatory effects (e.g., prostaglandins and leukotrienes) and antiinflammatory activities (e.g., lipoxins and products derived from docosahexaenoic acid ...
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Is There a Role for Bioactive Lipids in the Pathobiology of Diabetes Mellitus?
Frontiers in Endocrinology, 2017 Inflammation, decreased levels of circulating endothelial nitric oxide (eNO) and brain-derived neurotrophic factor (BDNF), altered activity of hypothalamic neurotransmitters (including serotonin and vagal tone) and gut hormones, increased concentrations ...
Undurti N. Das, Undurti N. Das
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Stereoselective syntheses and biological activities of E-series resolvins
, 2021 Recent research efforts focusing on the many mechanisms participating in the resolution of acute inflammation have uncovered a new genus of pro-resolving lipid mediators. These endogenous molecules include the lipoxins, resolvins, protectins and maresins,
Vik, Anders, Hansen, Trond Vidar
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Resolvin D1 and Resolvin D2 Govern Local Inflammatory Tone in Obese Fat [PDF]
The Journal of Immunology, 2012 Abstract The unprecedented increase in the prevalence of obesity and obesity-related disorders is causally linked to a chronic state of low-grade inflammation in adipose tissue. Timely resolution of inflammation and return of this tissue to homeostasis are key to reducing obesity-induced metabolic dysfunctions.
Joan, Clària +4 more
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