Results 51 to 60 of about 10,096 (216)

Protectin and resolvin gut inflammation [PDF]

Science, 2017
Inflammation Even when laced with syrup, cod-liver oil is disgusting, but it is an important source of omega-3-docosapentaenoic fatty acid (DPA). After being swallowed, DPA is converted into specialized proresolving lipid mediators (SPMs), including protectin and resolvin.
openaire   +2 more sources

Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

Journal of Lipid Research, 2013
Placental inflammation is associated with several pregnancy disorders. Inflammation is limited by anti-inflammatory and proresolving mechanisms, the latter partly mediated by resolvins and protectins derived from omega-3 polyunsaturated fatty acids (n ...
Megan L. Jones, Peter J. Mark, Jeffrey A. Keelan, Anne Barden, Emilie Mas, Trevor A. Mori, Brendan J. Waddell   +6 more
doaj   +1 more source

Is Lipid Metabolism of Value in Cancer Research and Treatment? Part II: Role of Specialized Pro-Resolving Mediators in Inflammation, Infections, and Cancer

Metabolites
Acute inflammation is the body’s first defense in response to pathogens or injury that is partially governed by a novel genus of endogenous lipid mediators that orchestrate the resolution of inflammation, coined specialized pro-resolving mediators (SPMs).
Muhammad Usman Babar, Ala F. Nassar, Xinxin Nie, Tianxiang Zhang, Jianwei He, Jacky Yeung, Paul Norris, Hideki Ogura, Anne Muldoon, Lieping Chen, Stephania Libreros   +10 more
doaj   +1 more source

Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2.

Journal of Nutritional Biochemistry, 2019
High-fat diet (HFD)-fed mice show obesity with development of liver steatosis and a proinflammatory state without establishing an inflammatory reaction.
F. Echeverría, R. Valenzuela, A. Espinosa, A. Bustamante, D. Álvarez, D. González-Mañán, M. Ortíz, S. Soto-Alarcón, L. Videla   +8 more
semanticscholar   +1 more source

The Role of Resolvins: EPA and DHA Derivatives Can Be Useful in the Prevention and Treatment of Ischemic Stroke

International Journal of Molecular Sciences, 2020
Introduction: Most ischemic strokes develop as a result of atherosclerosis, in which inflammation plays a key role. The synthesis cascade of proinflammatory mediators participates in the process induced in the vascular endothelium and platelets ...
Nikola Tułowiecka, D. Kotlęga, P. Prowans, M. Szczuko   +3 more
semanticscholar   +1 more source

Resolvin D1 and Aspirin-Triggered Resolvin D1 Promote Resolution of Allergic Airways Responses [PDF]

The Journal of Immunology, 2012
Abstract Asthma is a disease of airway inflammation that in most cases fails to resolve. The resolution of inflammation is an active process governed by specific chemical mediators, including D-series resolvins. In this study, we determined the impact of resolvin D1 (RvD1) and aspirin-triggered RvD1 (AT-RvD1) on the development of ...
Alexandre P, Rogerio, Oliver, Haworth, Roxanne, Croze, Sungwhan F, Oh, Mohib, Uddin, Troy, Carlo, Michael A, Pfeffer, Rebekah, Priluck, Charles N, Serhan, Bruce D, Levy   +9 more
openaire   +2 more sources

The role of Resolvin D1 in liver diseases

Prostaglandins & Other Lipid Mediators, 2022
The liver is a parenchymatous organ closely related to immunity, detoxification and metabolism of the three major nutrients. The inflammatory response is a protective mechanism of the body to eliminate harmful stimuli. However, continuous inflammatory stimulation leads to occurrence of many liver diseases and brings great social burden.
Mei, Yang, Xian-Qi, Song, Mei, Han, Hui, Liu   +3 more
openaire   +2 more sources

Current experimental methods to investigate the impact of specialized pro-resolving lipid mediators on Sjögren’s syndrome

Frontiers in Immunology, 2023
Sjögren’s syndrome is a chronic inflammatory autoimmune disease characterized by diminished secretory function of the exocrine glands. Although extensive investigation has been done to understand Sjögren’s syndrome, the causes of the disease are as yet ...
Harim T. dos Santos, Harim T. dos Santos, Kihoon Nam, Kihoon Nam, Diana Gil, Diana Gil, Diana Gil, Venkata Yellepeddi, Venkata Yellepeddi, Olga J. Baker, Olga J. Baker, Olga J. Baker   +11 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Resolvin D5 Inhibits Neuropathic and Inflammatory Pain in Male But Not Female Mice: Distinct Actions of D-Series Resolvins in Chemotherapy-Induced Peripheral Neuropathy

Frontiers in Pharmacology, 2019
Earlier studies have demonstrated that essential fatty acid-derived specialized pro-resolving mediators (SPMs) promote the resolution of inflammation and pain. However, the potential analgesic actions of SPMs in chemotherapy-induced peripheral neuropathy
Xin Luo, Yun Gu, Xueshu Tao, C. Serhan, R. Ji   +4 more
semanticscholar   +1 more source