Results 71 to 80 of about 8,166 (214)
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Anti-inflammatory effects of resolvins in diabetic nephropathy: Mechanistic pathways
The incidence of diabetes mellitus is growing rapidly. The exact pathophysiology of diabetes is unclear, but there is increasing evidence of the role of the inflammatory response in both developing diabetes as well as its complications.
Atkin S.L. +4 more
core +1 more source
Resolvins and aliamides: Lipid autacoids in ophthalmology – What promise do they hold? [PDF]
Resolvins are a novel class of lipid-derived endogenous molecules (autacoids) with potent immunomodulating properties, which regulate the resolution phase of an active immune response.
Chiosi, Flavia +2 more
core +1 more source
Omega fatty acids and resolution of inflammation: A new twist in an old tale
Identification of the factors that regulate immune tolerance and control the appearance of exacerbated inflammatory conditions is crucial for the development of new therapies of inflammatory and autoimmune diseases.
Mittal Antush +2 more
doaj
Most polyunsaturated fatty acids have the minimal 1,4-cis,cis-pentadiene configuration to be oxygenated into a conjugated diene hydroperoxide. This product is usually reduced into the corresponding hydroxy derivative by cell glutathione peroxidases.
Lagarde Michel
doaj +1 more source
Context: Periodontitis and diabetes are universally prevalent diseases which are interlinked with each other. Inflammatory products released both by the microorganisms, and the host plays a pivotal role in causing both the diseases.
Prathyusha Rampally +4 more
doaj +1 more source
Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold +2 more
wiley +1 more source
The role of Resolvin D1 in liver diseases
The liver is a parenchymatous organ closely related to immunity, detoxification and metabolism of the three major nutrients. The inflammatory response is a protective mechanism of the body to eliminate harmful stimuli. However, continuous inflammatory stimulation leads to occurrence of many liver diseases and brings great social burden.
Mei, Yang +3 more
openaire +2 more sources
Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans [PDF]
Resolvins are omega-3 fatty acid derived potent bioactive lipids that resolve inflammation and modulate transient receptor potential channels. Exogenous administration of the resolvin precursor 17-HDHA shows a strong analgesic effect in animal models of ...
Ana M. Valdes +24 more
core +1 more source
Jie Deng,1 Lorne M Golub,2 Hsi-Ming Lee,2 Veena Raja,2 Francis Johnson,3 Allan Kucine,4 Wonsae Lee,5 Tian-Min Xu,1 Ying Gu6 1Department of Orthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral ...
Deng J +8 more
doaj

