Results 71 to 80 of about 10,096 (216)
A simple and rapid method for the extraction of D-series resolvins (RvD1, RvD2, RvD3, RvD4, RvD5) released into Leibovitz’s L-15 complete medium by head kidney cells from Atlantic salmon and the further determination of liquid chromatography triple ...
Pedro Araujo +4 more
doaj +1 more source
A Modular, Enantioselective Synthesis of Resolvins D3, E1, and Hybrids
Resolvins D3 and E1 are important signaling molecules in the resolution of inflammation. Here, we report a convergent and flexible strategy to prepare these natural products using Hiyama–Denmark coupling of five- and six-membered cyclic alkenylsiloxanes ...
Felix Urbitsch +4 more
semanticscholar +1 more source
Abstract Purpose Anterior cruciate ligament (ACL) injuries are increasing in children and adolescents and reconstruction (ACLR) is now frequently performed in this population. Paediatric patients remain at higher risk of reinjury, possibly due to delayed graft remodelling.
Caroline de Pesters +7 more
wiley +1 more source
Stereoselective syntheses and biological activities of E-series resolvins.
Recent research efforts focusing on the many mechanisms participating in the resolution of acute inflammation have uncovered a new genus of pro-resolving lipid mediators. These endogenous molecules include the lipoxins, resolvins, protectins and maresins,
A. Vik, T. Hansen
semanticscholar +1 more source
Back to the Eosinophil: Resolvin Spatiotemporal Regulation
Eosinophils are granulocytes that home to sites of infection and injury, where they can initiate and drive host defense and allergic inflammatory responses. Eosinophil accumulation at different mucosal sites, including the lung and gastrointestinal tract, is also strongly linked with disease pathogenesis (1–3).
Donovan, Chantal +2 more
openaire +2 more sources
Omega fatty acids and resolution of inflammation: A new twist in an old tale
Identification of the factors that regulate immune tolerance and control the appearance of exacerbated inflammatory conditions is crucial for the development of new therapies of inflammatory and autoimmune diseases.
Mittal Antush +2 more
doaj
Pathogenic trypanosomatids (Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp.) are protozoan parasites that cause neglected diseases affecting millions of people in Africa, Asia, and the Americas.
Rodrigo A. López-Muñoz +7 more
doaj +1 more source
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley +1 more source
Most polyunsaturated fatty acids have the minimal 1,4-cis,cis-pentadiene configuration to be oxygenated into a conjugated diene hydroperoxide. This product is usually reduced into the corresponding hydroxy derivative by cell glutathione peroxidases.
Lagarde Michel
doaj +1 more source
Context: Periodontitis and diabetes are universally prevalent diseases which are interlinked with each other. Inflammatory products released both by the microorganisms, and the host plays a pivotal role in causing both the diseases.
Prathyusha Rampally +4 more
doaj +1 more source

