Anti-inflammatory effects of resolvins in diabetic nephropathy: Mechanistic pathways
The incidence of diabetes mellitus is growing rapidly. The exact pathophysiology of diabetes is unclear, but there is increasing evidence of the role of the inflammatory response in both developing diabetes as well as its complications.
Atkin S.L. +4 more
core +1 more source
Association of the resolvin precursor 17-HDHA, but not D- or E- series resolvins, with heat pain sensitivity and osteoarthritis pain in humans [PDF]
Resolvins are omega-3 fatty acid derived potent bioactive lipids that resolve inflammation and modulate transient receptor potential channels. Exogenous administration of the resolvin precursor 17-HDHA shows a strong analgesic effect in animal models of ...
Ana M. Valdes +24 more
core +1 more source
Periodontitis as a Model for Inflammatory Uncoupling of Bone Remodeling
Periodontitis can be viewed as a state of inflammatory uncoupling of bone remodeling, in which excessive osteoclast‐mediated resorption coexists with impaired bone formation. This review integrates emerging insights from osteoimmunology, osteocyte biology, mechanobiology, aging, and resolution pathways to position periodontitis as an accessible in vivo
Rafael Scaf de Molon +4 more
wiley +1 more source
Atividade anti-hiperalgésica das resolvinas no modelo de dor inflamatória articular em ratos [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2011A descoberta de que a resolução da inflamação é um processo ativo, no qual vários mediadores lipídicos
Garcia, Juliana Fabris Lima
core
Introduction: Most ischemic strokes develop as a result of atherosclerosis, in which inflammation plays a key role. The synthesis cascade of proinflammatory mediators participates in the process induced in the vascular endothelium and platelets ...
Małgorzata Szczuko +3 more
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Resolvins as potential candidates for the treatment of major depressive disorder
In contrast with the delayed onset of therapeutic responses and relatively low efficacy of currently available monoamine-based antidepressants, a single subanesthetic dose of ketamine, an N-methyl-D-aspartate receptor antagonist, produces rapid and ...
Satoshi Deyama +2 more
core +1 more source
Abstract Peri‐implant diseases are dysbiosis‐mediated inflammatory disorders that occur in susceptible hosts. Antimicrobials and immunomodulatory agents therefore might be pertinent as adjunctive measures in the treatment of such disorders. The aim of this narrative review was to examine the existing evidence and assess the effectiveness of emerging ...
Alberto Monje +3 more
wiley +1 more source
The effect of osteoblast addition to critical defect and the effect of D4 and D5 resolvins to calvaria [PDF]
OBJECTIVE: A calvarial defect model was used to study the effect of additions of osteoblasts in both a grid culture and implantation onto chick embryo membrane.
Shah, Nischit
core
Omega fatty acids and resolution of inflammation: A new twist in an old tale
Identification of the factors that regulate immune tolerance and control the appearance of exacerbated inflammatory conditions is crucial for the development of new therapies of inflammatory and autoimmune diseases.
Mittal Antush +2 more
doaj
Novel and emerging antimicrobial strategies in the management of oral infections
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source

