Results 91 to 100 of about 7,733 (208)
Mediator-lipidomics: databases and search algorithms for PUFA-derived mediators
Lipid mediators (LMs) derived from PUFAs play important roles in health and disease. Databases and search algorithms are crucial, but currently unavailable, for accurate and prompt analysis of LMs via liquid chromatography-ultraviolet-tandem mass ...
Yan Lu +3 more
doaj +1 more source
Biosynthetic D‐calcium pantothenate and cyanocobalamin alleviate MPTP‐induced Parkinsonism in mice by modulating gut microbiota, restoring metabolic homeostasis, and inhibiting Endoplasmic Reticulum Stress. ABSTRACT Vitamin B5 (VB5) and Vitamin B12 (VB12) are essential micronutrients widely distributed in functional foods, yet their neuroprotective ...
Yaru Chen +6 more
wiley +1 more source
Understanding periodontal diseases and diabetes through resolvins
Thesis (M.A.)--Boston University PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request.
Cheng, David
core
An exuberant inflammatory response may exacerbate the primary tissue damage caused by injuries to the skin due to burns, surgery, excessive pressure, and other etiologies, thus increasing the time to heal.
François Berthiaume +2 more
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Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Osteoarthritis: Epidemiology, Diagnosis, and Treatment
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
Most polyunsaturated fatty acids have the minimal 1,4-cis,cis-pentadiene configuration to be oxygenated into a conjugated diene hydroperoxide. This product is usually reduced into the corresponding hydroxy derivative by cell glutathione peroxidases.
Lagarde Michel
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Resolvins and aliamides: Lipid autacoids in ophthalmology – What promise do they hold?
Resolvins are a novel class of lipid-derived endogenous molecules (autacoids) with potent immunomodulating properties, which regulate the resolution phase of an active immune response.
Chiosi, Flavia +2 more
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Jie Deng,1 Lorne M Golub,2 Hsi-Ming Lee,2 Veena Raja,2 Francis Johnson,3 Allan Kucine,4 Wonsae Lee,5 Tian-Min Xu,1 Ying Gu6 1Department of Orthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral ...
Deng J +8 more
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Targeting Neutrophil Apoptosis for Enhancing the Resolution of Inflammation
Resolution of acute inflammation is an active process that requires inhibition of further leukocyte recruitment and removal of leukocytes from inflamed sites. Emigrated neutrophils undergo apoptosis before being removed by scavenger macrophages.
Driss El Kebir, János G. Filep
doaj +1 more source

