Results 21 to 30 of about 7,733 (208)

Differential effects of resolvin D1 and resolvin E1 on cementoblast function

open access: yesJournal of Periodontology, 2023
AbstractBackgroundResolvins are endogenous mediators of the resolution of inflammation. They are derived from omega‐3 polyunsaturated fatty acid precursors. Resolvin D1 (RvD1) and Resolvin E1 (RvE1) are the best‐characterized members for actively promoting periodontal regeneration in experimental animal models.
Bozkurt, Serife Buket   +2 more
openaire   +2 more sources

Resolvins and inflammatory pain [PDF]

open access: yesF1000 Medicine Reports, 2011
Resolvins are a group of molecules derived from omega-3 fatty acids. They are part of a biochemical program that allows inflamed tissues to return to homeostasis once the need for the inflammatory response is over. Resolvins act in very low dose ranges in vitro and in vivo.
Sommer, Claudia, Birklein, Frank
openaire   +2 more sources

Trypanosoma cruzi Produces the Specialized Proresolving Mediators Resolvin D1, Resolvin D5, and Resolvin E2 [PDF]

open access: yesInfection and Immunity, 2018
ABSTRACT Trypanosoma cruzi is a protozoan parasite that causes Chagas disease (CD). CD is a persistent, lifelong infection affecting many organs, most notably the heart, where it may result in acute myocarditis and chronic cardiomyopathy. The pathological features include myocardial inflammation and fibrosis.
Romain A. Colas   +15 more
openaire   +3 more sources

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Specialized Pro-Resolving Mediators in Neuroinflammation: Overview of Studies and Perspectives of Clinical Applications

open access: yesMolecules, 2022
Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in the inflammation environment, preventing an overreaction of the organism and ...
Mariarosaria Valente   +4 more
doaj   +1 more source

Resolving Resolvins

open access: yesChemistry & Biology, 2013
In this issue of Chemistry & Biology, Dalli and colleagues report the chemical structures of resolvin D3 (RvD3) and aspirin-triggered RvD3, derived from the ω3-fatty acid docosahexaenoic acid. These compounds have a specific temporal appearance within inflammation resolution and display anti-inflammatory and proresolving properties.
Haeggström, Jesper Z., Hamberg, Mats
openaire   +2 more sources

Resolvins’ Obesity-Driven Deficiency: The Implications for Maternal–Fetal Health [PDF]

open access: yes, 2022
Since pregnancy is already characterized by mild but significant inflammatory activity in physiological conditions, when complicated by obesity the probability of a persistent inflammatory state increases, with consequent multiple repercussions that add ...
Zanza C.   +4 more
core   +2 more sources

Therapeutic Effects of Specialized Pro-Resolving Lipids Mediators on Cardiac Fibrosis via NRF2 Activation

open access: yesAntioxidants, 2020
Heart disease is the number one mortality disease in the world. In particular, cardiac fibrosis is considered as a major factor causing myocardial infarction and heart failure. In particular, oxidative stress is a major cause of heart fibrosis.
Gyeoung Jin Kang   +2 more
doaj   +1 more source

Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia [PDF]

open access: yesThe American Journal of Pathology, 2016
Acute lung injury is a life-threatening condition caused by disruption of the alveolar-capillary barrier leading to edema, influx of inflammatory leukocytes, and impaired gas exchange. Specialized proresolving mediators biosynthesized from essential fatty acids, such as docosahexaenoic acid, have tissue protective effects in acute inflammation. Herein,
Jennifer K, Colby   +13 more
openaire   +2 more sources

Can endogenous lipid molecules serve as predictors and prognostic markers of coronary heart disease?

open access: yesLipids in Health and Disease, 2008
Dyslipidemia, and inflammatory markers: high-sensitivity C-reactive protein (hs-CRP), myeloperoxidase (MPO), lipoprotein associated phospholipase A2(Lp-PLA2), and lipid peroxides (LP) are insufficient to predict the onset, extent, and prognosis of CHD ...
Das Undurti N
doaj   +1 more source

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