Results 31 to 40 of about 1,153,543 (306)

Lipoxygenase-derived eicosanoids in myocardial ischaemia-reperfusion injury: the role of sensory C-fibres and TRPV1 [PDF]

open access: yes, 2010
PhDIt is well established that the 12-lipoxygenase (12-LOX) pathway of arachidonic acid (AA) metabolism is stimulated within the myocardium by episodes of ischaemia, and there is considerable evidence showing that eicosanoids derived via this pathway ...
Goddard, Alison
core   +3 more sources

Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity

open access: yesNature Communications, 2018
Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections.
Oliver Werz   +7 more
doaj   +1 more source

Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Diabetic patients are susceptible to renal ischemia-reperfusion injury, which leads to perioperative complications. Activation of NOD-like receptor protein 3 (NLRP3) inflammasome participates in the development of diabetes, and contributes to ...
Seung Hyun Kim   +5 more
doaj   +1 more source

Electroacupuncture Pretreatment Mitigates Myocardial Ischemia/Reperfusion Injury via XBP1/GRP78/Akt Pathway

open access: yesFrontiers in Cardiovascular Medicine, 2021
Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang   +9 more
doaj   +1 more source

Postconditioning: Reperfusion of “reperfusion injury” after hibernation [PDF]

open access: yesCardiovascular Research, 2006
The newly developed concept of postconditioning as a way of reducing reperfusion injury has been receiving much attention in the literature, both in basic science and clinical circles. Cardiovascular Research will be hosting a Spotlight Issue entitled “ Cardiac Protection by Pre- and Postconditioning ” in May of this year.
David, Garcia-Dorado   +1 more
openaire   +2 more sources

Application of a novel method for subsequent evaluation of sinusoids and postsinusoidal venules after ischemia-reperfusion injury of rat liver [PDF]

open access: yes, 1998
Although several intravital fluorescence microscopic studies demonstrated that microcirculatory derangement is induced during liver ischemia-reperfusion, these data were obtained from randomly selected microvascular areas and microvessels, Repeated ...
Todoroki, T.   +5 more
core   +1 more source

Lipid Mediator Informatics and Proteomics in Inflammation-Resolution

open access: yesThe Scientific World Journal, 2006
Lipid mediator informatics is an emerging area denoted to the identification of bioactive lipid mediators (LMs) and their biosynthetic profiles and pathways.
Yan Lu   +3 more
doaj   +1 more source

Lipid-Derived Mediators in Endogenous Anti-Inflammation and Resolution: Lipoxins and Aspirin-Triggered 15-epi-Lipoxins

open access: yesThe Scientific World Journal, 2002
It is well appreciated that lipid-derived mediators play key roles in inflammation and many other physiologic responses where multicellular processes are involved.
Charles N. Serhan, Nan Chiang
doaj   +1 more source

Reperfusion injury

open access: yesClinical Cardiology, 1990
AbstractThis article reviews the early and late morphologic changes associated with reperfusion of ischemic myocardium. If instituted within minutes of coronary artery occlusion, all reversibly injured myocardium is salvaged. Once some irreversibly injured myocardium is present, the usually bland region of coagulation necrosis is transformed into an ...
openaire   +2 more sources

MicroRNA-670 aggravates cerebral ischemia/reperfusion injury via the Yap pathway

open access: yesNeural Regeneration Research, 2021
Apoptosis is an important programmed cell death process involved in ischemia/reperfusion injury. MicroRNAs are considered to play an important role in the molecular mechanism underlying the regulation of cerebral ischemia and reperfusion injury. However,
Shi-Jia Yu   +4 more
doaj   +1 more source

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