Results 81 to 90 of about 965,659 (315)

Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy

Journal of Immunological Research, 2017
Acute kidney injury caused by ischemia and subsequent reperfusion is associated with a high rate of mortality and morbidity. Ischemia/reperfusion injury in kidney transplantation causes delayed graft function and is associated with more frequent episodes
A. Kezić, N. Stajić, F. Thaiss
semanticscholar   +1 more source

The effect of foot orthoses on midfoot pain and the volume of bone marrow lesions in the midfoot: a randomized mechanism of action study

Arthritis Care &Research, Accepted Article.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain and MRI‐confirmed midfoot BMLs.
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

Gender differences in plaque characteristics of nonculprit lesions in patients with coronary artery disease

BMC Cardiovascular Disorders, 2019
Background Although numerous reports suggest sex-related differences in atherosclerosis, limited data describing gender-associated differences in plaque morphology and composition are currently available.
Jiangtian Tian, Xuedong Wang, Jinwei Tian, Bo Yu   +3 more
doaj   +1 more source

Financial Distress and its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent chronic use of expensive disease modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or non‐inflammatory musculoskeletal disease (NIMSKD) completing the Functional
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

Update on ischemia-reperfusion injury in kidney transplantation: Pathogenesis and treatment.

World journal of transplantation, 2015
Ischemia/reperfusion injury is an unavoidable relevant consequence after kidney transplantation and influences short term as well as long-term graft outcome.
M. Salvadori, G. Rosso, E. Bertoni
semanticscholar   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Long non-coding RNA AK023617 orchestrates atherosclerosis by regulating the circadian rhythm of immunity-related GTPase family M protein in macrophages

Non-coding RNA Research
Acute coronary events show a diurnal rhythm, and atherosclerotic plaque vulnerability, as a histomorphological characteristic of major adverse cardiovascular events, is a key target for intervention. Although oscillating microRNAs reduce plaque stability
Rongzhe Lu, Hengxuan Cai, Yige Liu, Guanpeng Ma, Jiaxin Wang, Miao Yan, Zhenming Zhang, Bo Yu, Zhaoying Li, Shaohong Fang   +9 more
doaj   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

The Long Noncoding RNA MALAT1 Induces Tolerogenic Dendritic Cells and Regulatory T Cells via miR155/Dendritic Cell-Specific Intercellular Adhesion Molecule-3 Grabbing Nonintegrin/IL10 Axis

Frontiers in Immunology, 2018
By shaping T cell immunity, tolerogenic dendritic cells (tDCs) play critical roles in the induction of immune tolerance after transplantation. However, the role of long noncoding RNAs (lncRNAs) in the function and immune tolerance of dendritic cells (DCs)
Jian Wu, Jian Wu, Hanlu Zhang, Hanlu Zhang, Yang Zheng, Yang Zheng, Xiangyuan Jin, Mingyang Liu, Mingyang Liu, Shuang Li, Shuang Li, Qi Zhao, Qi Zhao, Xianglan Liu, Xianglan Liu, Yongshun Wang, Ming Shi, Shengnan Zhang, Shengnan Zhang, Jinwei Tian, Jinwei Tian, Yong Sun, Yong Sun, Maomao Zhang, Maomao Zhang, Bo Yu, Bo Yu   +26 more
doaj   +1 more source

Feasibility of a three-axis epicardial accelerometer in detecting myocardial ischemia in cardiac surgical patients [PDF]

, 2008
Per Steinar Halvorsen, Andreas Espinoza, Lars Albert Fleischer, Ole Jakob Elle, Lars Hoff, Runar Lundblad, Helge Skulstad, Thor Edvardsen, Halfdan Ihlen, Erik Fosse   +9 more
openalex   +1 more source