Results 61 to 70 of about 543,435 (265)

ESKD, Major Cardiovascular Events, and Death Associated With Systemic Inflammation

open access: yesKidney International Reports
Introduction: Systemic inflammation may play a role in the progression of chronic kidney disease (CKD) and in the development of major cardiovascular events (MACE).
Jean-Michel Halimi   +6 more
doaj   +1 more source

CNS-border associated macrophages respond to acute ischemic stroke attracting granulocytes and promoting vascular leakage

open access: yesActa Neuropathologica Communications, 2018
The central nervous system (CNS) contains several types of immune cells located in specific anatomic compartments. Macrophages reside at the CNS borders surrounding the brain vessels, in leptomeningeal spaces and the choroid plexus, where they interact ...
Jordi Pedragosa   +13 more
doaj   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon   +5 more
wiley   +1 more source

Psychological consequences of functional sequelae after rectal cancer treatment: a narrative review

open access: yesDiscover Psychology
Purpose Rectal cancer treatment relies on multimodal approaches including surgery, radiotherapy, and chemotherapy, which are frequently associated with persistent functional sequelae such as bowel dysfunction, stoma formation, and sexual or urinary ...
Nicolas Michot   +6 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

METABOLIC AND BEHAVIORAL EFFECTS OF KETOGENIC AND NON-KETOGENIC LOW-CARBOHYDRATE DIETS

open access: yesIBRO Neuroscience Reports, 2023
Ilya Smolensky   +4 more
doaj   +1 more source

Association between plaque characteristics and side-branch compromise in left main bifurcation lesions after a single-stent crossover technique: insights from an optical coherence tomography study

open access: yesFrontiers in Cardiovascular Medicine
BackgroundThe primary mechanism underlying side branch (SB) ostial compromise following main vessel (MV) stenting is the MV carina shift. However, the association between plaque characteristics or distribution and SB compromise remains unclear in ...
Jincheng Han   +27 more
doaj   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

DNMT1 deficiency promotes pulmonary vascular remodeling in pulmonary hypertension through epigenetic upregulation of BMP7

open access: yesRespiratory Research
Background Pulmonary hypertension (PH) is a progressive cardiopulmonary disorder marked by pathological vascular remodeling, predominantly driven by the hyperproliferation of pulmonary artery smooth muscle cells (PASMCs).
Yong-Bing Wang   +11 more
doaj   +1 more source

Intestinal Ischemia

open access: yesArchives of Pathology & Laboratory Medicine, 2002
Abstract Context.—As rejection in renal transplantation has become better controlled, gastrointestinal complications have become increasingly important. Ischemic colitis and colonic perforation are the most common of these lesions, contributing to morbidity and mortality in the early postoperative period.
Simpson L, Dee   +2 more
openaire   +2 more sources

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