Results 101 to 110 of about 1,279,230 (303)

Long-Term Prognosis after Transient Ischemic Attack and Stroke

, 2018
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Rothwell, PM, Pendlebury, ST, Lau, GKK
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Young Stroke Survivors With No Early Recurrence at High Long‐Term Risk of Adverse Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Approximately 8% to 21% of strokes affect adults aged 5× that of young controls (hazard ratio, 5.2; 95% CI, 2.8–9.4), compared with a 30% increase at 5 years for older patients (hazard ratio, 1.3; 95% CI, 1.3–1.4).
Jodi D. Edwards, Moira K. Kapral, M. Patrice Lindsay, Jiming Fang, Richard H. Swartz   +4 more
doaj   +1 more source

Vascular Imaging in Transient Ischemic Attack and Stroke

, 2018
link_to_subscribed_fulltex
Rothwell, PM, Pendlebury, ST, Lau, GKK
core   +1 more source

Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]

, 2009
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Demchuk, A., Lees, K.R., Kasner, S.E., Messe, S.R., Cucchiara, B., Levine, S.R., Lyden, P., Sansing, L., Tanne, D.   +8 more
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Ataque transitorio de isquemia, el heraldo del ictus Transient ischemic attack: the herald of stroke

Revista Cubana de Investigaciones Biomédicas, 2012
Introducción: el ataque transitorio de isquemia constituye una parte fundamental de la enfermedad cerebrovascular, en muchas ocasiones no bien diagnosticado por su corta duración, lo difícil de ver y sus variadas manifestaciones clínicas.
Javier Sánchez López, Isis Rodríguez Ribalta, Martha Beatriz Díaz Dehesa   +2 more
doaj  

Risk Factors Associated with Recurrent Strokes in Young and Elderly Patients: A Hospital-based Study

International Journal of Gerontology, 2015
Background: Recurrent stroke is often devastating, and can cause severe disability or death. Risk factors associated with recurrent strokes unrelated to atrial fibrillation have been well identified; however, it remains to be further elucidated whether ...
Guang-Rong Fu, Wei-Qiang Yuan, Wan-Liang Du, Zhong-Hua Yang, Na Fu, Hua-Guang Zheng, Zi-Xiao Li, Yu-Ming Huang, Yu-Mmei Zhang, Guang-Zheng Dai, Hua-Bing Wang, Jian-Mei Li, Jing-Dong Yi, Qing-Biao Yang, Hong-Jun Tian, Li-Nan He, Geng-Yu Li, Jia-Li Zhang, Li-Mei Yang, Yan Gao, Zi-Wei Fu   +20 more
doaj   +1 more source

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang, Jia Zhou, Wenqin Yuan, Tianjiao Zhao, Yunying Huang, Yingci Xia, Yuting Lin, Fei Li, Qiong Huang, Chong Liu, Kelong Ai, Qun Qin   +11 more
wiley   +1 more source

Cross‐Platform Proteomics and Machine Learning Algorithms Nominate Plasma Biomarkers of Stroke Diagnosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Blood‐based biomarkers for stroke subtyping could improve triage in emergency settings. We used cross‐platform proteomics to identify plasma biomarkers differentiating major stroke diagnostic groups.
Shubham Misra, Wooyoung Eric Jang, Sebastian Sanchez, Aditya Natu, Prateek Kumar, Michael Liu, Anmol Kaur, Victor Torres Lopez, Pinar Caglayan, Rolando Garcia‐Milian, Caroline M. Watson, Michael R. Frankel, Guido J. Falcone, Lauren H. Sansing, Srikant Rangaraju   +14 more
doaj   +1 more source