Results 71 to 80 of about 67,239 (252)

Ataque transitorio de isquemia, el heraldo del ictus Transient ischemic attack: the herald of stroke

Revista Cubana de Investigaciones Biomédicas, 2012
Introducción: el ataque transitorio de isquemia constituye una parte fundamental de la enfermedad cerebrovascular, en muchas ocasiones no bien diagnosticado por su corta duración, lo difícil de ver y sus variadas manifestaciones clínicas.
Javier Sánchez López, Isis Rodríguez Ribalta, Martha Beatriz Díaz Dehesa   +2 more
doaj  

Risk Factors Associated with Recurrent Strokes in Young and Elderly Patients: A Hospital-based Study

International Journal of Gerontology, 2015
Background: Recurrent stroke is often devastating, and can cause severe disability or death. Risk factors associated with recurrent strokes unrelated to atrial fibrillation have been well identified; however, it remains to be further elucidated whether ...
Guang-Rong Fu, Wei-Qiang Yuan, Wan-Liang Du, Zhong-Hua Yang, Na Fu, Hua-Guang Zheng, Zi-Xiao Li, Yu-Ming Huang, Yu-Mmei Zhang, Guang-Zheng Dai, Hua-Bing Wang, Jian-Mei Li, Jing-Dong Yi, Qing-Biao Yang, Hong-Jun Tian, Li-Nan He, Geng-Yu Li, Jia-Li Zhang, Li-Mei Yang, Yan Gao, Zi-Wei Fu   +20 more
doaj   +1 more source

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

Advanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Young Stroke Survivors With No Early Recurrence at High Long‐Term Risk of Adverse Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Approximately 8% to 21% of strokes affect adults aged 5× that of young controls (hazard ratio, 5.2; 95% CI, 2.8–9.4), compared with a 30% increase at 5 years for older patients (hazard ratio, 1.3; 95% CI, 1.3–1.4).
Jodi D. Edwards, Moira K. Kapral, M. Patrice Lindsay, Jiming Fang, Richard H. Swartz   +4 more
doaj   +1 more source

Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes

Advanced Science, EarlyView.
This review synthesizes advances in bone organoid engineering and evaluates their potential to model diabetic bone fragility. Current in vitro and animal models do not fully recapitulate diabetes‐associated skeletal phenotypes. Cell‐based and scaffold‐based bone organoids are discussed as complementary approaches to reconstruct multicellular bone ...
Shuangzhe Lin, Karthikeyan Narayanan, Deepak Vashishth   +2 more
wiley   +1 more source

Cross‐Platform Proteomics and Machine Learning Algorithms Nominate Plasma Biomarkers of Stroke Diagnosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Blood‐based biomarkers for stroke subtyping could improve triage in emergency settings. We used cross‐platform proteomics to identify plasma biomarkers differentiating major stroke diagnostic groups.
Shubham Misra, Wooyoung Eric Jang, Sebastian Sanchez, Aditya Natu, Prateek Kumar, Michael Liu, Anmol Kaur, Victor Torres Lopez, Pinar Caglayan, Rolando Garcia‐Milian, Caroline M. Watson, Michael R. Frankel, Guido J. Falcone, Lauren H. Sansing, Srikant Rangaraju   +14 more
doaj   +1 more source

Human Papillomavirus Status and the Risk of Cerebrovascular Events Following Radiation Therapy for Head and Neck Cancer

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundRadiation therapy (RT) is a standard treatment for head and neck cancer; however, it is associated with inflammation, accelerated atherosclerosis, and cerebrovascular events (CVEs; stroke or transient ischemic attack). Human papillomavirus (HPV)
Daniel Addison, Sara B. Seidelmann, Sumbal A. Janjua, Hamed Emami, Pedro V. Staziaki, Travis R. Hallett, Bálint Szilveszter, Michael T. Lu, Richard P. Cambria, Udo Hoffmann, Annie W. Chan, Lori J. Wirth, Tomas G. Neilan   +12 more
doaj   +1 more source

Adipocyte‐Derived Exosomal miR‐5099 Mitigates M1 Macrophage Polarization and Adipose Inflammation via c‐Met/NF‐κB Axis to Improve Metabolic Health

Advanced Science, EarlyView.
Celastrol upregulates adipocyte‐derived exosomal miR‐5099, suppressing the macrophage c‐Met/NF‐κB axis to mitigate pro‐inflammatory M1 polarization and adipose inflammation. These miR‐5099‐enriched exosomes also act as endocrine signals targeting the liver, muscle, and adipocytes to significantly enhance systemic insulin sensitivity.
Ping Tang, Lixin Tai, Hongxia Xu, Dongliang Zhu, Jiajia Li, Hao Feng, Jinghui Cui, Shuhai Lin, Li‐jun Di, Li Wang   +9 more
wiley   +1 more source

Transient cortical weakness following cerebral angiography: A new syndrome

Radiology Case Reports
Transient cortical blindness is a known complication of iodinated contrast administration and is believed to reflect osmotic injury or autoregulatory dysfunction of the posterior circulation.
Akash P. Kansagra, MD, MS, Richard Pham, BA, Arindam R. Chatterjee, MD, Christopher J. Moran, MD   +3 more
doaj   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source