Results 111 to 120 of about 393,837 (313)

Brachial Artery Constriction during Brachial Artery Reactivity Testing Predicts Major Adverse Clinical Outcomes in Women with Suspected Myocardial Ischemia: Results from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study [PDF]

, 2013
Background:Limited brachial artery (BA) flow-mediated dilation during brachial artery reactivity testing (BART) has been linked to increased cardiovascular risk.
Sedlak, TL, Bairey Merz, CN, Johnson, BD, Reis, SE, Pepine, CJ   +4 more
core   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Unexplained chest/epigastric pain in patients with normal endoscopy as a predictor for ischemic heart disease and mortality: A Danish 10-year cohort study

BMC Gastroenterology, 2008
Background Normal upper endoscopy may be a marker of ischemic heart disease in patients with unexplained chest/epigastric pain. Methods We examined the 10-year risk of ischemic heart disease and mortality in a cohort of 386 Danish patients with chest ...
Funch-Jensen Peter, Drewes Asbjørn, Gregersen Hans, Dethlefsen Claus, Nørgård Bente, Munk Estrid, Sørensen Henrik   +6 more
doaj   +1 more source

Adiposity, adipokines, and risk of incident stroke in older men [PDF]

, 2013
<p>Background and Purpose—The association between adiposity and adipocytes and risk of stroke in older adults is uncertain. We have examined the association between adiposity measures and adipocytes (adiponectin and leptin) with incident stroke ...
Shaper, A.G., Whincup, P.H., Lennon, L., Sattar, N., Wannamethee, S.G.   +4 more
core   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Overview of the traditional therapy and recent advances in the management of ischemic heart diseases

, 2015
ischemic heart disease is the leading cause at the present,this thesis demonstrates the risk factors of the disorders, possible ways to prevent it as well as the therapeutic aspects, including pharmacological and surgical treatments.
Marzouk, Manal
core  

Analyzing Recent Coronary Heart Disease Mortality Trends in Tunisia between 1997 and 2009.

, 2013
BACKGROUND: In Tunisia, Cardiovascular Diseases are the leading causes of death (30%), 70% of those are coronary heart disease (CHD) deaths and population studies have demonstrated that major risk factor levels are increasing.
Critchley Julia A., Julia A Critchley, Ben Mansour Nadia, Habiba Ben Romdhane, Saidi Olfa, O'Flaherty, M, Capewell, S, Saidi, O, Martin O’Flaherty (391936), Romdhane Habiba Ben, Critchley, JA, Julia A. Critchley (409777), Ben Romdhane, H, Simon Capewell, O’Flaherty Martin, Olfa Saidi, Martin O'Flaherty, Ben Mansour, N, Nadia Ben Mansour, Capewell Simon, Nadia Ben Mansour (409776), Simon Capewell (21152), Olfa Saidi (409775), Habiba Ben Romdhane (300820)   +23 more
core   +1 more source

Soluble ST2 is regulated by p75 neurotrophin receptor and predicts mortality in diabetic patients with critical limb ischemia [PDF]

, 2012
<b>Objective—</b><p></p> The p75 neurotrophin receptor (p75^NTR) contributes to diabetes mellitus−induced defective postischemic neovascularization.
Spinetti, Gaia, Ambra Gotti, Losa, Sergio, Christa Noehammer, Ezio Faglia, Orazio Fortunato, Caporali, Andrea, Emanueli, Costanza, Nailor, Audrey, Cardinali, Alessandro Cardinali, Alessandro Cardinali, Manuela Hofner, Noehammer, Christa, Sergio Losa, Gotti, Ambra, Miller, Ashley M, Vierlinger, Klemens, Fortunato, Orazio, Ashley M. Miller, Tijana Mitić, Costanza Emanueli, Miller, Ashley M., Hofner, Manuela, Caporali, Andrea; id_orcid, Cardinali, Alessandro, Meloni, Marco, Paolo Madeddu, Gaia Spinetti, Faglia, Ezio, Klemens Vierlinger, Audrey Nailor, Mitić, Tijana, Andrea Caporali, Madeddu, Paolo, Marco Meloni   +34 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

ASSESSMENT OF CONCOMITANT PATHOLOGY AND OUTCOMES OF CHRONIC HEART FAILURE OF VARIOUS ETIOLOGIES IN PATIENTS OF THE SOUTHERN REGION OF INDIA

Байкальский медицинский журнал
Relevance. Сhronic heart failure is a widespread pathology due to the high incidence of hypertension and coronary artery disease. Several million new cases of heart failure are reported in India every year.
Andrey S. Ankudinov, Oman Soman Suman, Konstantin S. Tolkachev   +2 more
doaj   +1 more source