Results 101 to 110 of about 6,399,450 (255)

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Analyzing Recent Coronary Heart Disease Mortality Trends in Tunisia between 1997 and 2009. [PDF]

, 2013
BACKGROUND: In Tunisia, Cardiovascular Diseases are the leading causes of death (30%), 70% of those are coronary heart disease (CHD) deaths and population studies have demonstrated that major risk factor levels are increasing.
Critchley Julia A., Julia A Critchley, Ben Mansour Nadia, Habiba Ben Romdhane, Saidi Olfa, O'Flaherty, M, Capewell, S, Saidi, O, Martin O’Flaherty (391936), Romdhane Habiba Ben, Critchley, JA, Julia A. Critchley (409777), Ben Romdhane, H, Simon Capewell, O’Flaherty Martin, Olfa Saidi, Martin O'Flaherty, Ben Mansour, N, Nadia Ben Mansour, Capewell Simon, Nadia Ben Mansour (409776), Simon Capewell (21152), Olfa Saidi (409775), Habiba Ben Romdhane (300820)   +23 more
core   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

Cotinine-assessed second-hand smoke exposure and risk of cardiovascular disease in older adults [PDF]

, 2010
Objectives: To examine whether second-hand smoke (SHS) exposure measured by serum cotinine is associated with increased coronary heart disease (CHD) and stroke risk among contemporary older British adults.
Jefferis, BJ, Lawlor, DA, Feyerabend, C, Whincup, PH, Doig, M, Cook, DG, Ebrahim, S, Wannamethee, SG, McMeekin, L   +8 more
core   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Overview of the traditional therapy and recent advances in the management of ischemic heart diseases

, 2015
ischemic heart disease is the leading cause at the present,this thesis demonstrates the risk factors of the disorders, possible ways to prevent it as well as the therapeutic aspects, including pharmacological and surgical treatments.
Marzouk, Manal
core  

Job strain, job demands, decision latitude, and risk of coronary heart disease within the Whitehall II study [PDF]

, 2003
STUDY OBJECTIVES: To investigate the association between job strain and components of the job strain model and coronary heart disease (CHD) risk. DESIGN: Prospective cohort study (Whitehall II study).
Kuper, H, Marmot, M
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

ASSESSMENT OF CONCOMITANT PATHOLOGY AND OUTCOMES OF CHRONIC HEART FAILURE OF VARIOUS ETIOLOGIES IN PATIENTS OF THE SOUTHERN REGION OF INDIA

Байкальский медицинский журнал
Relevance. Сhronic heart failure is a widespread pathology due to the high incidence of hypertension and coronary artery disease. Several million new cases of heart failure are reported in India every year.
Andrey S. Ankudinov, Oman Soman Suman, Konstantin S. Tolkachev   +2 more
doaj   +1 more source