Results 91 to 100 of about 393,837 (313)

Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke

Advanced Healthcare Materials, EarlyView.
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan, Damien Levard, Eloïse Lemarchand, Amal Boublay, Charly Helaine, Jolan Malherbe, Mikaël Naveau, Didier Goux, Igor Khalin, Ankita Talukdar, Cheun Pelleter, Charlène Jacqmarcq, Erwan Baudron, Isabelle Bardou, Sara Martinez de Lizarrondo, Maxime Gauberti, Denis Vivien, Antoine Philippe Fournier   +17 more
wiley   +1 more source

Snps Gln27Glu Polymorphism of β2-Adrenoceptor Gene and Carbohydrate and Lipid Metabolism Impairment in Obese Patients with Ischemic Heart Disease

Mìžnarodnij Endokrinologìčnij Žurnal, 2016
This article estimates the role of Gln27Glu polymorphism of β2-adrenergic receptors gene in forming violations of carbohydrate and lipid metabolism in obese patients with ischemic heart disease.
O.I. Kadykova
doaj   +1 more source

The Correlation of Adiponectin, and Visfatin Serum Levels With Ischemic Heart Disease in Postmenopausal women: A population-Based Study

Iranian South Medical Journal, 2017
Background: There is a controversial evidence about adiponectin role in cardiovascular diseases and visfatin role has been suggested in pathogenesis of coronary artery disease.
Hossein Darabi, zahra Behzadi, Taliaeh Zahedi, Mohammadreza Pourbehi, Samad Akbarzadeh, Afshin Ostovar1, Majid Assadi, Haerinejad, Zahra Sanjdideh, Iraj Nabipour   +9 more
doaj  

Chronobiologic Aspects of Ischemic Coronary Artery Disease.

, 1996
Convincing evidence is now available suggesting that several unfavorable cardiovascular events respect a well-defined diurnal pattern in their occurrence.
Isidoro Sciré RISICHELLA, MANFREDINI, Roberto, Carmelo FERSINI, M. Gallerani, I. Fisichella, Massimo GALLERANI, F. Chierici, FERSINI, Carmelo, Anna Maria MIRIZIO, R. Salmi, Franco CHIERICI, P. Notarstefano, A. M. Mirizio, Adriana TASSI, Pasquale NOTARSTEFANO, Roberto MANFREDINI, A. Tassi, Francesco PORTALUPPI, Emanuela RIZZIOLI, E. Rizzioli, Raffaella SALMI, PORTALUPPI, Francesco   +21 more
core   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium

, 2008
Background— Clinical trials indicate a beneficial effect of intracoronary infusion of progenitor cells on myocardial function in patients with ischemic heart disease.
Dimmeler, S, Aicher, A, Röver, R, Brenner, W, Schächinger, V, Döbert, N, Fichtlscherer, S, Seeger, FH, Diener, J, Assmus, B, Menzel, C, Zeiher, AM   +11 more
core  

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

CANDESARTAN IN CARDIOLOGY PRACTICE

Медицинский совет, 2017
The most significant risk factor for the development of cardiovascular diseases such as myocardial infarction, ischemic heart disease, chronic heart failure, is arterial hypertension (AH).
N. A. Dzhaiani
doaj   +1 more source

Evidence based diabetology : strategies to prevent macrovascular disease and to reduce mortality [PDF]

, 2006
Diabetes mellitus (DM) is the most common metabolic disease worldwide and the number of newly diagnosed cases is increasing. DM is strongly associated with a number of devastating chronic late complications, including retinopathy, nephropathy and ...
Allemann, Sabin Liliane
core   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

Advanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng, Yanlin Guo, Liumi Jiang, Jing Luo, Yan Liu, Ziwei Yuan, Pingyang Ke, Ran Duan, Fei Xiao   +8 more
wiley   +1 more source