Results 81 to 90 of about 583,933 (296)

How periodontal disease may contribute to cardiovascular disease [PDF]

, 2000
No abstract ...
Kinane, D.F., Lowe, G.D.O.
core   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]

, 2008
An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Erin Lane, Heng Ma, Ji Li, Jingying Wang, Jun Ren, Lin Leng, Richard Bucala, Wenkui Wang   +7 more
core   +1 more source

Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]

, 2019
No abstract ...
Berry, C, Ford, TJ, Hainsworth, AH, Kaski, JC, Pereira, AC, Sidik, N, Touyz, RM   +6 more
core   +2 more sources

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Ventricular rhythm disturbances during computer spirography in patients with stable ischemic heart disease and chronic obstructive pulmonary disease: clinical and functional predictors of occurrence

Zaporožskij Medicinskij Žurnal, 2019
The purpose of the study is to determine the predictors of cardiac rhythm disturbance during spirography in patients with a combination of stable coronary heart disease and chronic obstructive pulmonary disease. Materials and methods.
Yu. M. Mostovoi, L. V. Rasputina, D. V. Didenko, A. O. Dovhan   +3 more
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

Advanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu, Yuan Wang, Yanjun Cai, Ruixin Guo, Shunhua Liu, Tingting Chen, Tingting Sun, Ruiheng Huo, Tengwei Liu, Qingfeng Lv, Xietong Wang   +10 more
wiley   +1 more source

Mechanism of selective lesion of the cardiovascular system in psycho-emotional stress [PDF]

A species predisposition to hypertensive and ischemic heart disease occurs in mammals only at the level of primates, and is associated with social regulation of biological reactions.
Repin, Y. M., Startsev, V. G.
core   +1 more source

Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation) [PDF]

, 2016
Introduction: Atrial fibrillation is an independent risk factor of thromboembolism. Women with atrial fibrillation are at a higher overall risk for stroke compared to men with atrial fibrillation. The aim of this study was to evaluate for sex differences
Abdul-Rahim, Azmil, Acciarresi, Monica, Ageno, Walter, Agnelli, Giancarlo, Akhtar, Naveed, Alberti, Andrea, Antonenko, Kateryna, Baldi, Antonio, Barlinn, Kristian, Baronello, Mario M., Becattini, Cecilia, Bodechtel, Ulf, Bono, Giorgio, Bovi, Paolo, Carletti, Monica, Carolei, Antonio, Caso, Valeria, Chiti, Alberto, Consoli, Domenico, Cordier, Maria, Corea, Francesco, Csiba, Laszló, De Lodovici, Maria Luisa, Del Sette, Massimo, Deleu, Dirk, Denti, Licia, Doronin, Boris, D’Amore, Cataldo, D’Anna, Antonio, Falocci, Nicola, Galati, Franco, Gerber, Johannes, Gialdini, Gino, Guideri, Francesca, Ibrahim, Faisal, Imberti, Davide, Kepplinger, Jessica, Lees, Kennedy R., Lorenzini, Gianni, Marcheselli, Simona, Martini, Giuseppe, Masotti, Luca, Melikyan, Gayane, Michel, Patrik, Monaco, Serena, Mosconi, Maria G., Orlandi, Giovanni, Paciaroni, Maurizio, Padovani, Alessandro, Pallesen, Lars-Peder, Papageorgiou, Sokratis G., Pezzini, Alessandro, Pieroni, Alessio, Poli, Loris, Putaala, Jukka, Remillard, Suzette, Rigatelli, Alberto, Rueckert, Christina, Sacco, Simona, Scoditti, Umberto, Sohn, Sung-Il, Szabó6, Lilla, Tassi, Rossana, Tassinari, Tiziana, Tatlisumak, Turgut, Tiseo, Cindy, Toni, Danilo, Tsivgoulis, Georgios, Vadik, Kostantinos, Vanacker, Peter, Venti, Michele, Volodina, Vera, Zabzuni, Dorjan   +72 more
core   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source