Results 31 to 40 of about 364,761 (266)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Evaluation of Ischemic Heart Disease [PDF]

Heart Failure Clinics, 2009
Approximately two thirds of patients with heart failure have underlying coronary artery disease. In the setting of ischemic heart disease, cardiovascular magnetic resonance has demonstrated usefulness in two ways: for the detection of coronary artery disease and for the assessment of myocardial viability in consideration for revascularization.
Dipan J, Shah, Han W, Kim, Raymond J, Kim   +2 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Differences in stroke and ischemic heart disease mortality by occupation and industry among Japanese working-aged men

SSM: Population Health, 2016
Occupation- and industry-based risks for stroke and ischemic heart disease may vary among Japanese working-aged men. We examined the differences in mortality rates between stroke and ischemic heart disease by occupation and industry among employed ...
Koji Wada, Hisashi Eguchi, David Prieto-Merino   +2 more
doaj   +1 more source

Short and long term exposure to air pollution increases the risk of ischemic heart disease

Scientific Reports, 2021
Previous studies have suggested an increased risk of ischemic heart disease related to air pollution. This study aimed to explore both the short-term and long-term effects of air pollutants on the risk of ischemic heart disease after adjusting for ...
So Young Kim, Sang Hoon Kim, Jee Hye Wee, Chanyang Min, Sang-Min Han, Seungdo Kim, Hyo Geun Choi   +6 more
doaj   +1 more source

Ischemic Heart Disease in Women

Journal of the American College of Cardiology, 2006
This supplement is intended to provide a specialized forum to overview new information on the pathophysiology, diagnosis, and outcomes of women with suspected ischemic heart disease (IHD). Led by Women's Ischemic Syndrome Evaluation (WISE) study investigators and other experts, the scientific summaries contained in this supplement will permit sharing ...
Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida. ( host institution ), Pepine, Carl J.   +1 more
openaire   +3 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Elaboration of New Medical Technology for Predicting the Risk of Ischemic Heart Disease in the Workers of the Coal Industry

Acta Biomedica Scientifica, 2019
Background. Ischemic heart disease is the leading cause of death in the majority of developed countries, including Russia. It determines the importance of elaboration of individual risk prediction of ischemic heart disease for primary prevention.Aim: to ...
N. I. Panev, S. N. Filimonov, O. Yu. Korotenko, R. N. Panev, N. Ya. Paneva   +4 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Mitophagy in ischemic heart disease: molecular mechanisms and clinical management

Cell Death and Disease
The influence of the mitochondrial control system on ischemic heart disease has become a major focus of current research. Mitophagy, as a very crucial part of the mitochondrial control system, plays a special role in ischemic heart disease, unlike ...
Shujuan Xu, Zihan Wang, Fan Guo, Yehao Zhang, Han Peng, Huiyu Zhang, Zixin Liu, Ce Cao, Gaojie Xin, Yuan Yuan Chen, Jianhua Fu   +10 more
doaj   +1 more source