Results 41 to 50 of about 6,399,450 (255)

Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression [PDF]

open access: yes, 2004
<p><b>Background and Purpose:</b> Early clinical progression of ischemic stroke is common and is associated with increased risk of death and dependency.
Lowe, G.D.O.   +4 more
core   +1 more source

Heterogeneity in national U.S. mortality trends within heart disease subgroups, 2000–2015

open access: yesBMC Cardiovascular Disorders, 2017
Background The long-term downward national U.S. trend in heart disease-related mortality slowed substantially during 2011–2014 before turning upward in 2015.
Stephen Sidney   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The stem-cell application in ischemic heart disease: Basic principles, specifics and practical experience from clinical studies [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2015
Longer life duration, different clinical presentations of coronary disease, as well as high incidence of comorbidity in patients with ischemic heart disease have led to an increase in the incidence of ischemic heart failure. Despite numerous and
Banović Marko   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Psychological distress, physical illness, and risk of coronary heart disease [PDF]

open access: yes, 2005
Study objective: The aims of this study are to confirm the association between psychological distress and coronary heart disease (CHD) using an epidemiological community study with hospital admissions data and to examine if any association is explained ...
Rasul, F.   +7 more
core   +1 more source

О ФАКТОРАХ РИСКА, ОСОБЕННОСТЯХ ТЕЧЕНИЯ И КРИТЕРИЯХ ДИАГНОСТИКИ ИШЕМИЧЕСКОЙ БОЛЕЗНИ ПОЧЕК У БОЛЬНЫХ ИШЕМИЧЕСКОЙ БОЛЕЗНЬЮ СЕРДЦА

open access: yesАрхивъ внутренней медицины, 2013
Ischemic renal disease for a long time has no specific symptoms. This work is aimed at finding markers of early diagnosis of ischemic renal disease in patients with coronary heart disease.
О. Н. Сигитова   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng   +4 more
wiley   +1 more source

Elaboration of New Medical Technology for Predicting the Risk of Ischemic Heart Disease in the Workers of the Coal Industry

open access: yesActa Biomedica Scientifica, 2019
Background. Ischemic heart disease is the leading cause of death in the majority of developed countries, including Russia. It determines the importance of elaboration of individual risk prediction of ischemic heart disease for primary prevention.Aim: to ...
N. I. Panev   +4 more
doaj   +1 more source

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