Results 51 to 60 of about 364,761 (266)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Space conglomerates of mortality due to cancer, ischemic heart disease and ischemic cerebrovascular disease in Santiago de Cuba province

Medisan, 2023
Introduction: One of the aspects that more interest raises regarding the geographical distribution of mortality due to cancer is the formation of space conglomerates.
Armando Ernesto Pérez Cala, Edgar Benítez Sánchez, Nadina Travieso Ramos   +2 more
doaj  

Autophagy in Ischemic Heart Disease [PDF]

Circulation Research, 2009
Autophagy is a major catabolic pathway by which mammalian cells degrade and recycle macromolecules and organelles. It plays a critical role in removing protein aggregates, as well as damaged or excess organelles, to maintain intracellular homeostasis and to keep the cell healthy. In the heart, autophagy occurs at low levels under normal conditions, and
Asa B, Gustafsson, Roberta A, Gottlieb
openaire   +2 more sources

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Burden of ischemic heart disease mortality attributable to physical inactivity in Brazil

Revista de Saúde Pública, 2018
OBJECTIVE To analyze if the burden of ischemic heart disease mortality trend attributed to physical inactivity in Brazil differs from the global estimates.
Diego Augusto Santos Silva, Deborah Carvalho Malta, Maria de Fatima Marinho de Souza, Mohsen Naghavi   +3 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Ischemic heart disease in the elderly.

Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1985
老年者の虚血性心疾患は冠状動脈自体の動脈硬化性病変に加え心臓の生理的老化や他臓器障害など複雑に関与している. 急性心筋梗塞の臨床像, 選択的冠状動脈所見, 病理学的検索の3面から老年者の虚血性心疾患の特徴について検討した. 急性心筋梗塞例中70歳以上の老年者72例を非老年者128例と対比した. 老年者群の特徴は加齢とともに女性の占める率が増加し, 梗塞部位では心内膜下梗塞が24%と高率であった. 冠状動脈硬化危険因子中高脂血症, 肥満, 喫煙は有意に低率であった. 心不全, 心室頻拍・細動, 心房細動の合併率は有意に高く, 死亡率は25%で, 非老年者群の13%に比し有意に高かった.選択的冠状動脈造影で75%以上の有意の狭窄を呈した65歳以上の81例を40歳以下の若年者群と対比検討した ...
Kanoh, Tatsuji, Shimizu, Mitsuru
openaire   +3 more sources

Ischemic heart disease in women [PDF]

Revista Latino-Americana de Enfermagem, 2011
Nowadays, Coronary Diseases (CDs) represent the main mortality cause in men and women, but there are gender differences regarding their presentation, progression and the way the disease is tackled. This study mainly focuses on reviewing literature about the CD and its gender approach.
Sancho Cantus, David, Solano Ruiz, María del Carmen   +1 more
openaire   +4 more sources

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

Ventricular rhythm disturbances during computer spirography in patients with stable ischemic heart disease and chronic obstructive pulmonary disease: clinical and functional predictors of occurrence

Zaporožskij Medicinskij Žurnal, 2019
The purpose of the study is to determine the predictors of cardiac rhythm disturbance during spirography in patients with a combination of stable coronary heart disease and chronic obstructive pulmonary disease. Materials and methods.
Yu. M. Mostovoi, L. V. Rasputina, D. V. Didenko, A. O. Dovhan   +3 more
doaj   +1 more source