Results 101 to 110 of about 11,054 (137)
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Myocardial, neural and vascular aspects of ischemic preconditioning
Life Sciences, 1996Ischemic preconditioning can be obtained with brief coronary occlusions. It has been studied in different animal species including dogs, pigs, rabbits and rats. The suggested duration of the occlusions ranges from four periods of 5 min, separated from each other by 5 min of reperfusion, to one period of 2.5 min. In addition to the reduction of the size
G, Losano, D, Gattullo, P, Pagliaro
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Molecular and Cellular Biochemistry, 1995
It was the aim of this study to investigate (1) whether preconditioning modifies the fatty acid (FA) composition of myocardial phospholipids (PL), (2) whether a previous modification of membrane PL composition by the administration of coconut oil or fish oil influences the preconditioning, and (3) to compare the protective effects of preconditioning to
S, al Makdessi +4 more
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It was the aim of this study to investigate (1) whether preconditioning modifies the fatty acid (FA) composition of myocardial phospholipids (PL), (2) whether a previous modification of membrane PL composition by the administration of coconut oil or fish oil influences the preconditioning, and (3) to compare the protective effects of preconditioning to
S, al Makdessi +4 more
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EFFECTIVENESS OF ISCHEMIC PRECONDITIONING ON LONG-TERM MYOCARDIAL PRESERVATION
Transplantation, 1998This study was designed to assess whether the protective effect of ischemic preconditioning can be adapted for myocardium undergoing 6 hr of ischemia.Eighteen isolated rat hearts were perfused with oxygen-bicarbonated Krebs-Henseleit buffer in the Langendorff mode for 35 min (group A, controls) or perfused in the Langendorff apparatus for 20 min ...
M, Hachida +6 more
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Ischemic preconditioning reduces neutrophil accumulation and myocardial apoptosis
The Annals of Thoracic Surgery, 1999This study tested the hypothesis that ischemic preconditioning (IP) inhibits myocardial apoptosis after a short period of ischemia and reperfusion.In 9 anesthetized dogs, the left anterior descending (LAD) coronary artery was occluded for 30 min and reperfused for 3 h (control), while in 9 others, LAD occlusion was preceded by 5 min of occlusion and 5 ...
N P, Wang +7 more
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Limitation of infarct size by myocardial ischemic preconditioning
Basic Research in Cardiology, 1996Myocardial ischemic preconditioning (IP) has caught the attention and imagination of researchers throughout the world (7). And for good reason: the magnitude of protection against ischemic injury conferred by IP is tremendous, far surpassing that offered by past pharmacological therapies. Although the original description of IP focused on limitation of
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Myocardial ischemic preconditioning and mitochondrial F1F0-ATPase activity
Molecular and Cellular Biochemistry, 2000A short period of ischemia followed by reperfusion (ischemic preconditioning) is known to trigger mechanisms that contribute to the prevention of ATP depletion. In ischemic conditions, most of the ATP hydrolysis can be attributed to mitochondrial F1F0-ATPase (ATP synthase).
F, Bosetti +4 more
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Ischemic preconditioning, myocardial stunning, and hibernation: Basic aspects
American Heart Journal, 1999Ischemic preconditioning, myocardial stunning, and hibernation: basic aspects.
FERRARI, Roberto +5 more
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Ischemic preconditioning increases myocardial O-GlcNAc glycosylation
Scandinavian Cardiovascular Journal, 2013Through the hexosamine biosynthetic pathway (HBP) proteins are modified by O-linked-β-N-acetylglucosamine (O-GlcNAc), which acts as a stress sensor. Augmentation of O-GlcNAc confers cardioprotection against ischemia- reperfusion injury, but its role in ischemic preconditioning (IPC) is unknown.
Vibjerg Jensen, Rebekka +4 more
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Ischemic Preconditioning and Apoptosis in Myocardial Ischemia
2003An emerging body of evidence has now been accumulated to indicate the existance of a highly organized type of cell death, apoptosis, in the pathogenesis of a variety of cardiovascular diseases (30, 84). This process of cell death is a fundamentally important biological process that involves cell proliferation and differentiation to control tissue and ...
Dipak K. Das, Nilanjana Maulik
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Regional differences of myocardial infarct development and ischemic preconditioning
Basic Research in Cardiology, 2004The spatial and temporal development of myocardial infarction depends on the area at risk (AAR), the severity and duration of blood flow reduction (energy supply) as well as on heart rate and regional wall function (energy demand). Both supply and demand can vary within the AAR of a given heart, potentially resulting in differences in infarct ...
Rainer, Schulz +3 more
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