Results 121 to 130 of about 23,302 (228)

Enhanced Na\u3csup\u3e+\u3c/sup\u3e/H\u3csup\u3e+\u3c/sup\u3e Exchange During Ischemia and Reperfusion Impairs Mitochondrial Bioenergetics and Myocardial Function [PDF]

open access: yes, 2008
Inhibition of Na+/H+ exchange (NHE) during ischemia reduces cardiac injury due to reduced reverse mode Na+/Ca2+ exchange. We hypothesized that activating NHE-1 at buffer pH 8 during ischemia increases mitochondrial oxidation, Ca2+ overload, and reactive ...
Aldakkak, Mohammed   +4 more
core   +1 more source

Review paper
The interaction of coronary microembolization and ischemic preconditioning: A third window of cardioprotection through TNF-alpha

open access: yesArchives of Medical Science, 2007
With an unstable atherosclerotic coronary plaque, episodes of myocardial ischemia associated with release of debris and microembolization and subsequent restoration of more or less sufficient coronary blood flow can precede ultimate plaque rupture ...
Philipp Heusch   +5 more
doaj  

Myocardial protection in cardiac surgery: a comprehensive review of current therapies and future cardioprotective strategies

open access: yesFrontiers in Medicine
Cardiac surgery with cardiopulmonary bypass results in global myocardial ischemia–reperfusion injury, leading to significant postoperative morbidity and mortality.
Pascal Chiari   +3 more
doaj   +1 more source

Protective ischemia in cardiology. Myocardial conditioning forms

open access: yesКардиоваскулярная терапия и профилактика, 2011
The review describes the phenomena of ischemic myocardial preconditioning, conditioning, and postconditioning, as well as the relevant molecular mechanisms, in patients with coronary heart disease.
V. P. Lupanov, A. V. Maksimenko
doaj  

ATP-sensitive potassium channel subcellular trafficking during ischemia, reperfusion, and preconditioning [PDF]

open access: yes, 2016
Ischemic preconditioning is an endogenous cardioprotective mechanism in which short periods of ischemia and reperfusion provide protection when given before a subsequent ischemic event.
Ho, Joanne Cin-Yee
core   +1 more source

Anaesthetics and cardiac preconditioning. Part II. Clinical implications [PDF]

open access: yes, 2017
There is compelling evidence that preconditioning occurs in humans. Experimental studies with potential clinical implications as well as clinical studies evaluating ischaemic, pharmacological and anaesthetic cardiac preconditioning in the perioperative ...
Garcia, C.   +5 more
core  

Review paper
Postconditioning: a brief review

open access: yesArchives of Medical Science, 2006
Preconditioning represents the most effective form of cardioprotection that can be induced to attenuate the injury accompanying a longer lasting ischemia (=index ischemia) of sufficient duration and severity to cause myocardial necrosis.
Jochen D. Schipke   +4 more
doaj  

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