Results 1 to 10 of about 78,355 (309)

Lipopolysaccharide Preconditioning Restricts Microglial Overactivation and Alleviates Inflammation-Induced Depressive-like Behavior in Mice

open access: yesBrain Sciences, 2023
Overactive microglia and severe neuroinflammation play crucial roles in the development of major depressive disorder. Preconditioning with lipopolysaccharide (LPS) provides protection against severe neuroinflammation. However, administering high doses of
Haiping Yu   +4 more
doaj   +1 more source

Sevoflurane Preconditioning Increases Stress Resistance via IMB-2/DAF-16 in Caenorhabditis Elegans

open access: yesDose-Response, 2022
Sevoflurane preconditioning has been proved to possess therapeutic effects on stress. However, the mechanism by which sevoflurane preconditioning protects against stress remains unclear.
Yue Cao MMed   +5 more
doaj   +1 more source

Cerebral Ischemic Preconditioning Aggravates Death of Oligodendrocytes

open access: yesBiomolecules, 2022
Neurodegeneration can benefit from ischemic preconditioning, a natural adaptive reaction to sublethal noxious stimuli. Although there is growing interest in advancing preconditioning to preserve brain function, preconditioning is not yet considered ...
Teng Guan   +7 more
doaj   +1 more source

Perspectives on Drought Preconditioning Treatments With a Case Study Using Western Larch

open access: yesFrontiers in Plant Science, 2021
As the demand for drought hardy tree seedlings rises alongside global temperatures, there is a need to optimize nursery drought preconditioning methods to improve field performance of planted seedlings.
Ehren Reid Von Moler   +1 more
doaj   +1 more source

Hypertrophic preconditioning cardioprotection after myocardial ischaemia/reperfusion injury involves ALDH2-dependent metabolism modulation

open access: yesRedox Biology, 2021
Brief episodes of ischaemia and reperfusion render the heart resistant to subsequent prolonged ischaemic insult, termed ischaemic preconditioning.
Lei-Lei Ma   +7 more
doaj   +1 more source

Effects of Preconditioning on RBC Deformability in Critically Ill Patients

open access: yesCritical Care Explorations, 2022
OBJECTIVES:. RBCs from critically ill patients have depressed deformability, especially in sepsis. Prolonged exposure of RBCs from healthy volunteers to physiologic shear stress (the preconditioning technique) has been associated with improved ...
Anthony Moreau, MD   +3 more
doaj   +1 more source

Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning

open access: yesNeural Regeneration Research, 2020
Hypoxic preconditioning has been shown to improve hypoxic tolerance in mice, accompanied by the downregulation of DNA methyltransferases (DNMTs) in the brain.
Na Liu   +11 more
doaj   +1 more source

Preconditioning with associated blocking of Ca2+ inflow alleviates hypoxia-induced damage to pancreatic β-cells. [PDF]

open access: yesPLoS ONE, 2013
Beta cells of pancreatic islets are susceptible to functional deficits and damage by hypoxia. Here we aimed to characterize such effects and to test for and pharmacological means to alleviate a negative impact of hypoxia.Rat and human pancreatic islets ...
Zuheng Ma   +6 more
doaj   +1 more source

A study of optimal concentration range and time window of sevoflurane preconditioning for brain protection in MCAO rats

open access: yesBMC Anesthesiology, 2020
Background Sevoflurane preconditioning improves brain function in MCAO rats, and there are several methods for determining appropriate concentration and time windows for preconditioning.
Ying Deng   +6 more
doaj   +1 more source

Preconditioning as a method of neuroprotection in a model of brain infarct

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Preconditioning of ischemic and hypoxic type was investigated as a method of protecting brain against acute ischemic injury. The preconditioning methods were applied to experimental rats 24 h before the time when local brain infarct was done by middle ...
R. M. Khudoerkov   +4 more
doaj   +1 more source

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