Results 31 to 40 of about 134,907 (287)

Preconditioned Mesenchymal Stromal Cells to Improve Allotransplantation Outcome

Cells, 2021
Mesenchymal stromal cells (MSCs) are tissue-derived progenitor cells with immunomodulatory as well as multilineage differentiation capacities, and have been widely applied as cellular therapeutics in different disease systems in both preclinical models ...
Hui-Yun Cheng, Madonna Rica Anggelia, Cheng-Hung Lin, Chih-Fan Lin   +3 more
doaj   +1 more source

Effects of preconditioning with TNFα and IFNγ in angiogenic potential of mesenchymal stromal cell-derived extracellular vesicles

Frontiers in Cell and Developmental Biology, 2023
Introduction: Mesenchymal stromal cells (MSCs) have demonstrated therapeutic properties both in vitro and in vivo to treat various diseases, including anti-inflammatory, immunomodulatory and pro-angiogenic effects.
Sophie Cavallero, Samir Dekali, Nathalie Guitard, Héléne Théry, Carole Hélissey, Carole Hélissey, Sabine François   +6 more
doaj   +1 more source

Novel role for the innate immune receptor toll-like receptor 4 (TLR4) in the regulation of the wnt signaling pathway and photoreceptor apoptosis [PDF]

, 2012
Recent evidence has implicated innate immunity in regulating neuronal survival in the brain during stroke and other neurodegenerations. Photoreceptors are specialized light-detecting neurons in the retina that are essential for vision.
A Poltorak, A Wenzel, Abigail S. Hackam, AK Silva, AL Kindzelskii, Amit K. Patel, AO Edwards, AS Hackam, B Marsh, BJ Marsh, BJ Marsh, C Bowes, C Liu, C Niehrs, C Zhang, Chhinder P. Sodhi, CP Sodhi, CY Logan, D Jiang, David J. Hackam, DJ Kaczorowski, E Cario, E Chaum, E Okun, F Hua, F Limana, G Faraco, G Tezel, GA Limb, GM Seigel, GR Barile, GS Hageman, GT Higgins, H Yi, H Yi, HL Rosenzweig, HL Rosenzweig, HP Scholl, Hyun Yi, IA El-Ghrably, J Merenmies, J Qiu, J Watson, JK Shen, JR Caso, K Hoshino, K Kaarniranta, K Miyake, K Takeda, KP Mollen, L Barandon, L Minghetti, M Mizukami, MA Fragoso, Mauricio Martins Rodrigues, MD Gordon, MK Ko, MT Lotze, N Arimura, P Matzinger, PJ Franco, PY Leung, Q Xing, R Gauthier, R Gorina, R Kacimi, R Seitz, R Shechter, RM Vabulas, RR Caspi, RT Moon, S Lehnardt, S Lin, S Tell, S Walter, S Zareparsi, SC Gribar, SC Tang, SC Tang, SR Coats, T Ha, T Harada, T Harada, T Nakazawa, U Kilic, V Bocchini, V Fontaine, Y de Kozak, Y Xin, Z Tu   +89 more
core   +5 more sources

Microstructural Characterization of Spheroidal Graphite Irons: A Study of the Effect of Preconditioning Treatment

Metals, 2022
The effect of preconditioning treatments on the control and improvement of spheroidal graphite iron (SGI) microstructure was evaluated. In the melt, 0.15% of Zr-(Ca, Al) FeSi preconditioner was added into different conditions.
António Pires, Sónia Simões, Leander Michels, Emmanuelle Ott, Cathrine Hartung, Carlos Silva Ribeiro   +5 more
doaj   +1 more source

Preconditioning with Low-Dose Radiation Improves Antitumor Immunity and Survival in DC-Vaccinated Mice

Life
Preconditioning regimens are essential for the immunologic success of cell therapies like CAR T cells. Nevertheless, their effect on cancer vaccines is underexplored, and preconditioning regimens are generally absent from cancer vaccine clinical trials ...
Eric Kwon, Shelby Namen, Colin J. Willoughby, Solomon Kang, Gaurav Pandey, Alexander B. Kim, Carl J. DeSelm   +6 more
doaj   +1 more source

Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content

International Journal of Cardiology: Heart & Vasculature, 2015
Background: Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV content factors are most relevant for protective effects. We hypothesize that ischemic
Kristina Svennerholm, Pouria Rodsand, Urban Hellman, Marie Lundholm, Anders Waldenström, Björn Biber, Gunnar Ronquist, Michael Haney   +7 more
doaj   +1 more source

Repetitive spreading depolarization induces gene expression changes related to synaptic plasticity and neuroprotective pathways

Frontiers in Cellular Neuroscience, 2023
Spreading depolarization (SD) is a slowly propagating wave of profound depolarization that sweeps through cortical tissue. While much emphasis has been placed on the damaging consequences of SD, there is uncertainty surrounding the potential activation ...
Michela Dell’Orco, Jordan E. Weisend, Nora I. Perrone-Bizzozero, Andrew P. Carlson, Russell A. Morton, David N. Linsenbardt, C. William Shuttleworth   +6 more
doaj   +1 more source

Effect of Staged Preconditioning on BiochemicalMarkers in the Patients Undergoing Coronary Artery Bypass Grafting [PDF]

The present study has investigated the effectiveness of staged-preconditioning, in both remote and target organs. After IP the myocardial release of the biochemicalmarkers including, creatine phosphokinase (CPK), cardiac creatine kinase (CK-MB ...
باباپور, بهزاد, جعفری, ناصر, حسن پور, محمد, حسینیان, عدالت, دوستکامی, حسین, محمدزاده, علیرضا   +5 more
core   +3 more sources

Preconditioning for Allen-Cahn variational inequalities with non-local constraints [PDF]

, 2010
The solution of Allen-Cahn variational inequalities with mass constraints is of interest in many applications. This problem can be solved both in its scalar and vector-valued form as a PDE-constrained optimization problem by means of a primal-dual active
Blank, Luise, Sarbu, Lavinia, Stoll, Martin   +2 more
core   +1 more source

Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]

, 2020
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy, Heidrich, Felix M., Heinzel, Frank R., Ibrahim, Karim, Linke, Axel, Pfluecke, Christian, Quick, Silvio, Ruf, Tobias F., Strasser, Ruth H., Sveric, Krunoslav M., Troeger, Willi, Wiedemann, Stephan, Winzer, Robert, Youssef, Akram, Zhang, Kun   +14 more
core   +1 more source