Results 1 to 10 of about 6,531 (189)

Ischemic preconditioning protects against ischemic brain injury [PDF]

Neural Regeneration Research, 2016
In this study, we hypothesized that an increase in integrin αv ß 3 and its co-activator vascular endothelial growth factor play important neuroprotective roles in ischemic injury. We performed ischemic preconditioning with bilateral common carotid artery
Xiao-meng Ma, Mei Liu, Ying-ying Liu, Li-li Ma, Ying Jiang, Xiao-hong Chen   +5 more
doaj   +2 more sources

Ischemic preconditioning modifies mortality and inflammatory response [PDF]

Acta Cirúrgica Brasileira, 2016
PURPOSE: To evaluate the effect of ischemic preconditioning on mortality, inflammatory mediators and oxidative stress after intestinal ischemia and reperfusion.
Daniel Faria de Campos Pinheiro, Belchor Fontes, John Kioshi Shimazaki, Ana Maria Cattani Heimbecker, Jacqueline de Fátima Jacysyn, Samir Rasslan, Edna Frasson de Souza Montero, Edivaldo Massazo Utiyama   +7 more
doaj   +4 more sources

Cerebral Ischemic Preconditioning Aggravates Death of Oligodendrocytes [PDF]

Biomolecules, 2022
Neurodegeneration can benefit from ischemic preconditioning, a natural adaptive reaction to sublethal noxious stimuli. Although there is growing interest in advancing preconditioning to preserve brain function, preconditioning is not yet considered ...
Teng Guan, Ying Guo, Chengren Li, Ting Zhou, Qiang Yu, Chaoxian Yang, Guohui Zhang, Jiming Kong   +7 more
doaj   +2 more sources

Impact of combined ischemic preconditioning and melatonin on renal ischemia-reperfusion injury in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Studying the effect of melatonin pretreatment and ischemic preconditioning on renal ischemia-reperfusion injury (IRI). Materials and Methods: Forty-eight Wistar rats were randomized into six groups: control, sham operation, IRI (IRI in left
Hesham Abdel-Razek, Mohamed Soliman Rizk, Ghada Amer, Mona Kora, Aya Afifi, Sally Donia   +5 more
doaj   +1 more source

Effect of Remote Ischemic Preconditioning on Patient Survival and End Organ Injury During Elective Open Abdominal Aortic Surgery Repair: A Randomized Controlled Trial [PDF]

International Journal of Medical Arts, 2023
Background: Ischemic preconditioning is natural cytoprotective mechanism that can potentially protect end organs from ischemia. In examined instances having major vascular surgery, remote ischemia preconditioning provides straight-forward technique with ...
Mohamed Abdallah, Abdelrahman Elnaggar
doaj   +1 more source

Epsilon PKC increases brain mitochondrial SIRT1 protein levels via heat shock protein 90 following ischemic preconditioning in rats. [PDF]

PLoS ONE, 2013
Ischemic preconditioning is a neuroprotective mechanism whereby a sublethal ischemic exposure is protective against a subsequent lethal ischemic attack. We previously demonstrated that SIRT1, a nuclear localized stress-activated deacetylase, is vital for
John W Thompson, Kunjan R Dave, Isabel Saul, Srinivasan V Narayanan, Miguel A Perez-Pinzon   +4 more
doaj   +1 more source

Mechanisms and Prospects of Ischemic Tolerance Induced by Cerebral Preconditioning [PDF]

International Neurourology Journal, 2010
In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance.
Mohammad Iqbal Hossain Bhuiyan, Youn Jung Kim   +1 more
doaj   +1 more source

Alleviation of ischemic brain injury by exercise preconditioning is associated with modulation of autophagy and mitochondrial dynamics in cerebral cortex of female aged mice

Experimental Gerontology, 2023
Evidence from clinical studies and preclinical studies supports that exercise preconditioning can not only reduce the risk of stroke but also improve brain tissue and functional outcome after stroke.
Yuan-Yuan Qin, Shan-Yao Pan, Jia-Ru Dai, Qing-Mei Wang, Xun Luo, Zheng-Hong Qin, Li Luo   +6 more
doaj   +1 more source

Exercise Preconditioning Ameliorates Cognitive Impairment in Mice with Ischemic Stroke by Alleviating Inflammation and Modulating Gut Microbiota

Mediators of Inflammation, 2022
Several studies have demonstrated that exercise preconditioning is an effective means of alleviating poststroke cognitive impairment (PSCI). Mechanisms of regulating cognitive function have not been fully elucidated. Herein, the present study is aimed at
Heng Lv, Shasha Wang, Meihui Tian, Liya Wang, Jie Gao, Qitao Zhao, Zhaoyu Li, Xianjie Jia, Ying Yu   +8 more
doaj   +1 more source

Myocardial ischemic preconditioning in a porcine model leads to rapid changes in cardiac extracellular vesicle messenger RNA content

International Journal of Cardiology: Heart & Vasculature, 2015
Background: Extracellular vesicles (EVs) are thought to exert protective effects after ischemic and remote ischemic preconditioning. It is not well understood which EV content factors are most relevant for protective effects. We hypothesize that ischemic
Kristina Svennerholm, Pouria Rodsand, Urban Hellman, Marie Lundholm, Anders Waldenström, Björn Biber, Gunnar Ronquist, Michael Haney   +7 more
doaj   +1 more source